Enfermedades infecciosas
Actividades del grupo
Las infecciones hospitalarias y las asociadas con los cuidados sanitarios constituyen un problema importante de salud pública, tanto por la morbilidad y mortalidad que causan, como por el coste económico que generan, en especial en pacientes con alta complejidad, como los atendidos en nuestro hospital.
Desde la implantación del PROA en nuestro hospital, realizamos una atención diaria de todos los casos con bacteriemia o funguemia, así como de las infecciones asociadas a catéteres, procedimientos invasivos, diarrea por Clostridioides difficile…etc. Los resultados de este programa se reflejan en la mejoría del uso de antimicrobianos, la evidencia del descenso del uso de antimicrobianos de amplio espectro y de la incidencia contenida de infecciones por microorganismos multirresistentes en nuestra OSI.
En esta línea participamos en numerosos estudios multicéntricos y ensayos clínicos basados en la epidemiología, tratamientos antimicrobianos y pronóstico de las personas infectadas por microorganismos multirresistentes y somos activos en la divulgación de conocimiento tanto en nuestra actividad diaria con otros profesionales como en cursos de formación.
El Hospital Universitario Cruces es centro de referencia de trasplante de órgano sólido de la Comunidad (hepático y renal); muchos pacientes son remitidos a nuestras consultas para su valoración pretrasplante y atendemos las complicaciones infecciosas del período postrasplante.
La Endocarditis Infecciosa continúa siendo un proceso infeccioso con una mortalidad excesiva y con escasa modificación en la última década. Colaboramos muy activamente en el grupo nacional GAMES (Grupo de Apoyo al Manejo de la Endocarditis Infecciosa). En nuestro centro hemos creado un grupo multidisciplinar para la toma de decisiones de forma colegiada con otros especialistas relacionados con el manejo de esta patología. Analizamos los cambios producidos en la última década en la epidemiología de la endocarditis infecciosa, y tenemos especial interés en la precisión diagnóstica y el tratamiento quirúrgico oportuno. Gracias a esta participación hemos logrado visualizar nuestro trabajo diario en múltiples publicaciones nacionales e internacionales.
Las infecciones de prótesis osteoarticulares se asocian como es bien conocido con una importante morbilidad. Lideramos el grupo multidisciplinar de manejo de esta patología compleja e integramos nuestra experiencia a registros nacionales con difusión nacional e internacional.
La unidad de pie diabético de nuestro centro está conformada por numerosos especialistas con los que colaboramos en la atención de las complicaciones infecciosas de estos pacientes, atendidos en una consulta monográfica de nuestro servicio. Este grupo mantiene una actividad formativa y científica que refleja la larga trayectoria en esta patología.
Las infecciones en pacientes inmunodeprimidos por enfermedades onco-hematológicas y otros pacientes que reciben terapias inmunosupresoras y basadas en fármacos biológicos, como es el caso de las enfermedades autoinmunes, son muy prevalentes y pueden ser devastadoras debido al riesgo de adquisición de infecciones causadas por microorganismos oportunistas. Nuestra colaboración en su atención se refleja en numerosas publicaciones de estudios multicéntricos españoles dirigidos a su estudio.
Los pacientes con infecciones del viajero y tropicales reciben atención y seguimiento en una consulta monográfica cuya actividad es registrada en la red nacional REDIVI (Red cooperativa para el estudio de las Infecciones importadas por Viajeros e Inmigrantes) con participación de los especialistas nacionales más relevantes de este campo.
Las infecciones por microorganismos emergentes son hoy en día de inmenso interés por su desconocimiento y riesgo de epidemias o pandemias con rápida extensión geográfica debido a los movimientos migratorios o viajeros. La pandemia por SARS-CoV2 ha sido el mejor ejemplo de ello; así, a comienzos del 2020 nos vimos obligados a una actualización continuada del conocimiento científico generado para ofrecer la mejor asistencia posible a nuestros pacientes, a ofrecer terapia farmacológica de nueva generación participando en ensayos clínicos de interés mundial, así como a difundir las medidas del mejor manejo posible mediante protocolos actualizados para los clínicos del hospital y publicaciones científicas.
La infección por VIH constituye un problema de primera línea para los infectólogos desde sus inicios en la década de 1980-90. Hoy en día seguimos en la atención de personas que viven con VIH mediante una valoración holística en la que, además de los tratamientos retrovirales de eficacia conocida, el paciente es asistido en todos los acontecimientos relacionados con esta infección crónica. Entre estos destacamos la infección por VHC que, con la incorporación de los nuevos fármacos de acción directa, han logrado la curación en los últimos años incluso aquellos pacientes coinfectados con VIH y VHC. No obstante, continúa siendo un área de vigilancia de nuevas infecciones y control de aquellos ya tratados.
Por otro lado, nuestro centro es de referencia en trasplante de órgano sólido (hepático y renal) en personas que viven con VIH y desde sus comienzos, participamos como investigadores en registros nacionales, analizando datos epidemiológicos, complicaciones infecciosas y no infecciosas como el rechazo o fallo del injerto que desarrollan los pacientes.
Las infecciones de transmisión sexual son otra área de interés y asistencia en nuestro servicio dada su prevalencia ascendente, mediante una consulta monográfica donde los pacientes son remitidos desde los servicios de Urgencias u otros especialistas. Se realiza una atención precoz del problema infeccioso, así como educación y tratamiento para la prevención de las mismas en sujetos en riesgo.
Las enfermedades infecciosas afectan a pacientes de toda índole y atención por todo tipo de especialistas médicos. Nuestro grupo fomenta la formación continuada en el área de las enfermedades infecciosas mediante cursos acreditados. El objetivo es ampliar el conocimiento en aquellos profesionales que en su labor diaria requieren un adecuado manejo diagnóstico y terapéutico de las complicaciones infecciosas.
Coordinador/a del grupo
-
Elena Bereciartua Bastarrica
Coordinador de grupo
elena.bereciartuabastarrica@osakidetza.eus
CV resumen
Salto Alejandre S, Carretero Ledesma M, Camacho Martinez P, Berastegui Cabrera J, Infante C, Rodriguez Alvarez R, et al. Serum IFN-gamma and RNAemia temporal profiles as biomarkers of severe COVID-19 in solid organ transplant and immunocompetent patients. J Infect. 2023; 86(5): 529-533. DOI:10.1016/j.jinf.2023.01.019.
Sojo Dorado J, Lopez Hernandez I, Hernandez Torres A, Retamar Gentil P, de Lucas EM, Escola Verge L, et al. Effectiveness of fosfomycin trometamol as oral step-down therapy for bacteraemic urinary tract infections due to MDR Escherichia coli: a post hoc analysis of the FOREST randomized trial. J Antimicrob Chemother. 2023; 78(7): 1658-1666. DOI:10.1093/jac/dkad147.
Badia Cebada L, Carmezim J, Perez Rodriguez MT, Bereciartua E, Lopez LE, Montenegro MR, et al. Randomized Clinical Trial of the Need for Antibiotic Treatment for Low-Risk Catheter-Related Bloodstream Infection Caused by Coagulase-Negative Staphylococci. Antibiotics-Basel. 2023; 12(5). DOI:10.3390/antibiotics12050839.
Barbero Allende JM, Gomez Junyent J, Sorli Redo L, Rodriguez Pardo D, Murillo Rubio O, Fernandez Sampedro M, et al. Description of reinfection of joint prosthesis after 2-stage replacement (infection of the 2nd stage prosthesis): A multicenter study. Enferm Infecc Microbiol Clin (Engl Ed). 2023. DOI:10.1016/j.eimce.2023.07.002.
Escrihuela Vidal F, Berbel D, Fernandez Hidalgo N, Escola Verge L, Munoz P, Olmedo M, et al. Impact of Intermediate Susceptibility to Penicillin on Antimicrobial Treatment and Outcomes of Endocarditis Caused by Viridans and Gallolyticus Group Streptococci. Clin Infect Dis. 2023. DOI:10.1093/cid/ciad375.
Ramos Martinez A, Dominguez F, Munoz P, Marin M, Pedraz A, Farinas MC, et al. Clinical presentation, microbiology, and prognostic factors of prosthetic valve endocarditis. Lessons learned from a large prospective registry. PLoS One. 2023; 18(9): 290998-290998. DOI:10.1371/journal.pone.0290998.
Grillo S, Pujol M, Miró JM, López Contreras J, Euba G, Gasch O, et al. Cloxacillin plus fosfomycin versus cloxacillin alone for methicillin-susceptible Staphylococcus aureus bacteremia: a randomized trial. Nat Med. 2023. DOI:10.1038/s41591-023-02569-0.
Sojo Dorado J, Lopez Hernandez I, Rosso Fernandez C, Morales IM, Palacios Baena ZR, Hernandez Torres A, et al. Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections A Randomized Clinical Trial. JAMA Netw Open. 2022; 5(1). DOI:10.1001/jamanetworkopen.2021.37277.
Norman FF, Salvador F, Gullon B, Diaz Menendez M, Perez Ayala A, Rodriguez Guardado A, et al. Frequency and characteristics of HTLV in migrants: Results from the +Redivi collaborative network in Spain. J Travel Med. 2022; 29(7). DOI:10.1093/jtm/taac019.
Garcia Alvarez L, Garcia C, Munoz P, Farinas Alvarez MC, Cuadra MG, Fernandez Hidalgo N, et al. Bartonella Endocarditis in Spain: Case Reports of 21 Cases. Pathogens. 2022; 11(5). DOI:10.3390/pathogens11050561.
Martinez Perez Crespo PM, Rojas A, Lanz Garcia JF, Retamar Gentil P, Reguera Iglesias JM, Lima Rodriguez O, et al. Pseudomonas aeruginosa Community-Onset Bloodstream Infections: Characterization, Diagnostic Predictors, and Predictive Score Development-Results from the PRO-BAC Cohort. Antibiotics (Basel). 2022; 11(6). DOI:10.3390/antibiotics11060707.
Cerrada Romero C, Berastegui Cabrera J, Camacho Martinez P, Goikoetxea Aguirre J, Perez Palacios P, Santibanez S, et al. Excretion and viability of SARS-CoV-2 in feces and its association with the clinical outcome of COVID-19. Sci Rep. 2022; 12(1). DOI:10.1038/s41598-022-11439-7.
Mussa M, Martinez Perez Crespo PM, Lopez Cortes LE, Retamar Gentil P, Sousa Dominguez A, Goikoetxea Aguirre AJ, et al. Risk Factors and Predictive Score for Bacteremic Biliary Tract Infections Due to Enterococcus faecalis and Enterococcus faecium: a Multicenter Cohort Study from the PROBAC Project. Microbiol Spectr. 2022; 10(4): 5122-5122. DOI:10.1128/spectrum.00051-22.
Norman FF, Trevino Maruri B, Ruiz Giardin JM, Gullon Pena B, Salvador F, Serre N, et al. Trends in imported malaria during the COVID-19 pandemic, Spain ( plus Redivi Collaborative Network). J Travel Med. 2022; 29(6). DOI:10.1093/jtm/taac083.
Mejia Chew C, Carver PL, Rutjanawech S, Aranha Camargo LF, Fernandes R, Belga S, et al. Risk Factors for Nontuberculous Mycobacteria Infections in Solid Organ Transplant Recipients: A Multinational Case-Control Study. Clin Infect Dis. 2022. DOI:10.1093/cid/ciac608.
Montejano R, de la Calle Prieto F, Velasco M, Guijarro C, Queiruga Parada J, Jimenez Gonzalez M, et al. Tenofovir Disoproxil Fumarate/Emtricitabine and Baricitinib for Patients at High Risk of Severe Coronavirus Disease 2019: The PANCOVID Randomized Clinical Trial. Clin Infect Dis. 2023; 76(3): 116-125. DOI:10.1093/cid/ciac628.
Dominguez Cainzos J, Rodrigo Manjon A, Rodriguez Chinesta JM, Apodaka Diez A, Bonmati G, Bereciartua E. Abdominal aortic endograft infection. A decade of experience and literature review. Enferm Infecc Microbiol Clin (Engl Ed). 2022; 41(3): 155-161. DOI:10.1016/j.eimce.2022.07.002.
Alvarez Zaballos S, Gonzalez Ramallo V, Quintana E, Munoz P, De la Villa Martinez S, Farinas MC, et al. Multivalvular Endocarditis: A Rare Condition with Poor Prognosis. J Clin Med. 2022; 11(16). DOI:10.3390/jcm11164736.
van Melle JP, Roos Hesselink JW, Bansal M, Kamp O, Meshaal M, Pudich J, et al. Infective endocarditis in adult patients with congenital heart disease. Int J Cardiol. 2022; 370: 178-185. DOI:10.1016/j.ijcard.2022.10.136.
Fernandez Ruiz M, Bodro M, Gutierrez Martin I, Rodriguez Alvarez R, Ruiz Ruigomez M, Sabe N, et al. Isavuconazole for the Treatment of Invasive Mold Disease in Solid Organ Transplant Recipients: A Multicenter Study on Efficacy and Safety in Real-life Clinical Practice. Transplantation. 2022; 107(3): 762-773. DOI:10.1097/TP.0000000000004312.
Rombauts A, Infante C, de Lagos MAM, Alba J, Valiente A, Donado Mazarron C, et al. Impact of SARS-CoV-2 RNAemia and other risk factors on long-COVID: A prospective observational multicentre cohort study. J Infect. 2022; 86(2): 154-225. DOI:10.1016/j.jinf.2022.11.009.
Pericas JM, Ambrosioni J, Munoz P, de Alarcon A, Kestler M, Mari Hualde A et al. Prevalence of Colorectal Neoplasms Among Patients With Enterococcus faecalis Endocarditis in the GAMES Cohort (2008-2017). Mayo Clin Proc. 2021; 96(1): 132-146. DOI:10.1016/j.mayocp.2020.06.056.
Zenarruzabeitia O, Astarloa Pando G, Terren I, Orrantia A, Perez Garay R, Seijas Betolaza I et al. T Cell Activation, Highly Armed Cytotoxic Cells and a Shift in Monocytes CD300 Receptors Expression Is Characteristic of Patients With Severe COVID-19. Front Immunol. 2021; 12. DOI:10.3389/fimmu.2021.655934.
Duena L, Varona J, Bereciartua E, Lopez L. In the shadow of the pandemic. Enferm Infecc Microbiol Clin (Engl Ed). 2021. DOI:10.1016/j.eimc.2021.03.006.
Rodriguez Pardo D, del Toro MD, Guio Carrion L, Escudero Sanchez R, Fernandez Sampedro M, Garcia Viejo MA et al. Role of asymptomatic bacteriuria on early periprosthetic joint infection after hip hemiarthroplasty. BARIFER randomized clinical trial. Eur J Clin Microbiol Infect Dis. 2021; 40(11): 2411-2419. DOI:10.1007/s10096-021-04241-2.
Gioia F, Filigheddu MT, Corbella L, Fernandez Ruiz M, Lopez Medrano F, Perez Ayala A et al. Invasive aspergillosis in solid organ transplantation: Diagnostic challenges and differences in outcome in a Spanish national cohort (Diaspersot Study). Mycoses. 2021; 64(11): 1334-1345. DOI:10.1111/myc.13298.
Delgado E, Fernandez Garcia A, Perez Losada M, Moreno Lorenzo M, Fernandez Miranda I, Benito S et al. Identification of CRF89_BF, a new member of an HIV-1 circulating BF intersubtype recombinant form family widely spread in South America. Sci Rep. 2021; 11(1): 11442-11442. DOI:10.1038/s41598-021-90023-x.
Lucas A, Chamorro Tojeiro S, Llenas Garcia J, Salvador F, Zubero Z, Molina I et al. Imported leptospirosis in travellers and migrants in Spain: a study of the +REDIVI collaborative network. J Travel Med. 2021; 28(6). DOI:10.1093/jtm/taab095.
Pericas JM, Hernandez Meneses M, Munoz P, Alvarez Uria A, Pinilla Llorente B, de Alarcon A et al. Outcomes and Risk Factors of Septic Shock in Patients With Infective Endocarditis: A Prospective Cohort Study. Open Forum Infect Dis. 2021; 8(6): 119-119. DOI:10.1093/ofid/ofab119.
Varela Barca L, Vidal Bonnet L, Farinas MC, Munoz P, Valerio Minero M, de Alarcon A et al. Analysis of sex differences in the clinical presentation, management and prognosis of infective endocarditis in Spain. Heart. 2021; 107(21): 1717-1724. DOI:10.1136/heartjnl-2021-319254.
Gutierrez Villanueva A, Munoz P, Delgado Montero A, Olmedo Samperio M, de Alarcon A, Gutierrez Carretero E et al. Mural Endocarditis: The GAMES Registry Series and Review of the Literature. Infect Dis Ther. 2021; 10(4): 2749-2764. DOI:10.1007/s40121-021-00490-y.
Delgado E, Fernandez Garcia A, Perez Losada M, Moreno Lorenzo M, Fernandez Miranda I, Benito S et al. Identification of CRF89_BF, a new member of an HIV-1 circulating BF intersubtype recombinant form family widely spread in South America (vol 11, 11442, 2021). Sci Rep. 2021; 11(1). DOI:10.1038/s41598-021-95679-z.
Dominguez Cainzos J, Rodrigo Manjon A, Rodriguez Chinesta JM, Apodaka Diez A, Bonmati G, Bereciartua E. Abdominal aortic endograft infection. A decade of experience and literature review. Enferm Infecc Microbiol Clin. 2021. DOI:10.1016/j.eimc.2021.06.018.
Mancheno Losa M, Lora Tamayo J, Fernandez Sampedro M, Rodriguez Pardo D, Munoz Mahamud E, Soldevila L et al. arthroplasty revision: A large multicenter cohort. J Infect. 2021; 83(5): 542-549. DOI:10.1016/j.jinf.2021.09.001.
Pando GA, Zenarruzabeitia O, Terren I, Orrantia A, Garay RP, Betolaza IS et al. T cell activation, highly armed cytotoxic cells and a shift in monocytes CD300 receptors expression in severe COVID-19. Eur J Immunol. 2021; 51: 267-267
Cardozo C, Cuervo G, Salavert M, Merino P, Gioia F, Fernández Ruiz M, et al. An evidence-based bundle improves the quality of care and outcomes of patients with candidaemia. J Antimicrob Chemother. 2020; 75(3): 730-737. DOI:10.1093/jac/dkz491.
Varela Barca L, Fernández Felix BM, Navas Elorza E, Mestres CA, Muñoz P, Cuerpo Caballero G, et al. Prognostic assessment of valvular surgery in active infective endocarditis: multicentric nationwide validation of a new score developed from a meta-analysis. Eur J Cardio-Thorac Surg. 2020; 57(4): 724-731. DOI:10.1093/ejcts/ezz328.
López Medrano F, Silva JT, Fernández Ruiz M, Vidal E, Origüen J, Calvo Cano A, et al. Oral fosfomycin for the treatment of lower urinary tract infections among kidney transplant recipients-Results of a Spanish multicenter cohort. Am J Transplant. 2020; 20(2): 451-462. DOI:10.1111/ajt.15614.
Gudiol C, Albasanz Puig A, Laporte Amargós J, Pallarès N, Mussetti A, Ruiz Camps I, et al. A clinical predictive model of multidrug resistance in neutropenic cancer patients with bloodstream infection due to Pseudomonas aeruginosa (IRONIC study). Antimicrob Agents Chemother. 2020; 64(4). DOI:10.1128/AAC.02494-19.
Len O, Los Arcos I, Aguado JM, Blanes M, Bodro M, Carratalà J, et al. Selection criteria of solid organ donors in relation to infectious diseases: A Spanish consensus. Transplant Rev. 2020; 34(2): 100528-100528. DOI:10.1016/j.trre.2020.100528.
Erdozain J, Pijoan J, Villar I, Nieto J, Ruiz Arruza I, Ruiz Irastorza G, et al. Ankle-brachial index and arterial vascular events in systemic lupus erythematosus patients: a 5-year prospective cohort. Clin Exp Rheumatol. 2020
San Juan R, Fernández Ruiz M, Ruiz Ruigómez M, López Medrano F, Ruiz Merlo T, Andrés A, et al. A new clinical and immuno-virological score for predicting the risk of late severe infection in solid organ transplant recipients: the CLIV Score. J Infect Dis. 2020; 222(3): 479-487. DOI:10.1093/infdis/jiaa090.
Bassetti M, Vena A, Meroi M, Cardozo C, Cuervo G, Giacobbe DR, et al. Factors associated with the development of septic shock in patients with candidemia: a post hoc analysis from two prospective cohorts. Crit Care. 2020; 24(1): 117-117. DOI:10.1186/s13054-020-2793-y.
Ramos Vivas J, Chapartegui González I, Fernández Martínez M, González Rico C, Fortún J, Escudero R, et al. Author Correction: Biofilm formation by multidrug resistant Enterobacteriaceae strains isolated from solid organ transplant recipients. Sci Rep. 2020; 10(1): 7452-7452. DOI:10.1038/s41598-020-60496-3.
Erdozain J, Pijoan J, Villar I, Nieto J, Ruiz Arruza I, Ruiz Irastorza G, et al. Ankle-brachial index and arterial vascular events in systemic lupus erythematosus patients: a 5-year prospective cohort. Clin Exp Rheumatol. 2020
Monte Armenteros J, Bereciartua Bastarrica E, Jimenez Maestre U, Guio Carrion L. [Bilateral pneumonia in a patient with Cushing's syndrome]. Rev Esp Quimioter. 2020; 33(4): 278-280. DOI:10.37201/req/001.2020.
Pujol M, Miro J, Shaw E, Aguado J, San Juan R, Puig Asensio M, et al. Daptomycin plus Fosfomycin versus Daptomycin Alone for Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis. A Randomized Clinical Trial. Clin Infect Dis. 2020; 72(9): 1517-1525. DOI:10.1093/cid/ciaa1081.
Ramos Martinez A, Pericas JM, Fernandez Cruz A, Munoz P, Valerio M, Kestler M, et al. Four weeks versus six weeks of ampicillin plus ceftriaxone in Enterococcus faecalis native valve endocarditis: A prospective cohort study. PLoS One. 2020; 15(8): 237011-237011. DOI:10.1371/journal.pone.0237011.
Paez Vega A, Cantisan S, Aguera ML, Suner M, Facundo C, Yuste JR, et al. Pretransplant CMV-specific T-cell immunity but not dose of antithymocyte globulin is associated with recovery of specific immunity after kidney transplantation. J Infect Dis. 2020; 223(7): 1205-1213. DOI:10.1093/infdis/jiaa503.
Prieto M, Gastaca M, Ruiz P, Ventoso A, Palomares I, Rodriguez Alvarez RJ, et al. A case of COVID-19 immediately after liver transplantation: Not only bad news. Ann Hepatobiliary Pancreat Surg. 2020; 24(3): 314-318. DOI:10.14701/ahbps.2020.24.3.314.
Merchante N, Rodriguez Fernandez M, Figueruela B, Rodriguez Arrondo F, Revollo B, Ibarra S, et al. Impact of HIV on the survival of hepatocellular carcinoma in hepatitis C virus-infected patients. Aids. 2020; 34(10): 1497-1507. DOI:10.1097/QAD.0000000000002578.
Ruiz Irastorza G, Pijoan J, Bereciartua E, Dunder S, Dominguez J, Garcia Escudero P, et al. Second week methyl-prednisolone pulses improve prognosis in patients with severe coronavirus disease 2019 pneumonia: An observational comparative study using routine care data. PLoS One. 2020; 15(9): 239401-239401. DOI:10.1371/journal.pone.0239401.
Goikoetxea Agirre AJ, Ibarrola Hierro M, Nieto Arana J, Martinez de Lagos MA. Vesicular (varicella-like) eruptions. Enferm Infecc Microbiol Clin. 2020. DOI:10.1016/j.eimc.2020.07.006.
Ramos Vivas J, Chapartegui Gonzalez I, Fernandez Martinez M, Gonzalez Rico C, Barrett J, Fortun J, et al. Adherence to Human Colon Cells by Multidrug Resistant Enterobacterales Strains Isolated From Solid Organ Transplant Recipients With a Focus on Citrobacter freundii. Front Cell Infect Microbiol. 2020; 10: 447-447. DOI:10.3389/fcimb.2020.00447.
Escuredo IM, Elorduy EV, Carrion LG, Segura JE, Arcarazo PI, Gutierrez JGJ. Mycobacterium abscessus Infection after Breast Lipotransfer: A Report of 2 Cases. PRS-GLOB OPEN. 2020; 8(8). DOI:10.1097/GOX.0000000000003063.
Pierrotti LC, Perez Nadales E, Fernandez Ruiz M, Gutierrez B, Hock Tan B, Carratala J, et al. Efficacy of beta-lactam/beta-lactamase inhibitors to treat extended-spectrum beta-lactamase-producing Enterobacterales bacteremia secondary to urinary tract infection in kidney transplant recipients (INCREMENT-SOT Project). Transpl Infect Dis. 2020; 23(3): 13520-13520. DOI:10.1111/tid.13520.
Farinas MC, Gonzalez Rico C, Fernandez Martinez M, Fortun J, Escudero R, Moreno A, et al. Oral decontamination with colistin plus neomycin in solid organ transplant recipients colonized by multidrug-resistant Enterobacterales: a multicenter, randomized, controlled, open-label, parallel-group clinical trial. Clin Microbiol Infect. 2020; 27(6): 856-863. DOI:10.1016/j.cmi.2020.12.016.
Salvador F, Trevino B, Chamorro Tojeiro S, Pou D, Herrero Martinez JM, Rodriguez Guardado A, et al. Epidemiological and clinical profile of immunosuppressed patients with imported strongyloidiasis: a substudy from a larger cohort of the plus REDIVI Spanish Collaborative Network. Pathog Glob Health. 2020; 115(2): 121-124. DOI:10.1080/20477724.2020.1857491.
de las Revillas FA, Sousa D, Ardanuy C, Garcia Vidal C, Montejo M, Rodriguez Alvarez R, et al. Healthcare-associated pneumonia: a prospective study in Spain. Rev Esp Quimioter. 2020; 33(5): 358-368. DOI:10.37201/req/067.2020.
Albasanz Puig A, Gudiol C, Parody R, Tebe C, Akova M, Araos R, et al. Impact of antibiotic resistance on outcomes of neutropenic cancer patients with Pseudomonas aeruginosa bacteraemia (IRONIC study): study protocol of a retrospective multicentre international study. Bmj Open. 2019; 9(5). DOI:10.1136/bmjopen-2018-025744.
Henriquez Camacho C, Serre M, Norman F, Sanchez Montalva A, Torrus D, Josune Goikoetxea A, et al. Clinicoepidemiological characteristics of viral hepatitis in migrants and travellers of the plus Redivi network. Travel Med Infect Dis. 2019; 29: 51-57. DOI:10.1016/j.tmaid.2019.02.001.
Benito N, Mur I, Ribera A, Soriano A, Rodriguez Pardo D, Sorli L, et al. The Different Microbial Etiology of Prosthetic Joint Infections according to Route of Acquisition and Time after Prosthesis Implantation, Including the Role of Multidrug-Resistant Organisms. J Clin Med. 2019; 8(5). DOI:10.3390/jcm8050673.
Salvador F, Trevino B, Chamorro Tojeiro S, Sanchez Montalva A, Maria Herrero Martinez J, Rodriguez Guardado A, et al. Imported strongyloidiasis: Data from 1245 cases registered in the plus REDIVI Spanish Collaborative Network (2009-2017). Plos Neglect Trop Dis. 2019; 13(5). DOI:10.1371/journal.pntd.0007399.
Morata L, Cobo J, Fernandez Sampedro M, Guisado Vasco P, Ruano E, Lora Tamayo J, et al. Safety and Efficacy of Prolonged Use of Dalbavancin in Bone and Joint Infections. Antimicrob Agents Chemother. 2019; 63(5). DOI:10.1128/AAC.02280-18.
Ramos Vivas J, Chapartegui Gonzalez I, Fernandez Martinez M, Gonzalez Rico C, Fortun J, Escudero R, et al. Biofilm formation by multidrug resistant Enterobacteriaceae strains isolated from solid organ transplant recipients. Sci Rep. 2019; 9(1): 8928-8928. DOI:10.1038/s41598-019-45060-y.
Manzardo C, Londono MC, Castells L, Testillano M, Luis Montero J, Penafiel J, et al. Direct-acting antivirals are effective and safe in HCV/HIV-coinfected liver transplant recipients who experience recurrence of hepatitis C: A prospective nationwide cohort study (vol 18, pg 2513, 2018). Am J Transplant. 2019; 19(2): 614-614. DOI:10.1111/ajt.15244.
Hirzel C, Ferreira VH, L'Huillier AG, Hoschler K, Limaye AP, Englund JA, et al. Humoral response to natural influenza infection in solid organ transplant recipients. Am J Transplant. 2019; 19(8): 2318-2328. DOI:10.1111/ajt.15296.
Lopez Alad R, Guiu A, Mar Mosquera M, Lopez Medrano F, Cofan F, Linares L, et al. Improvement in detecting cytomegalovirus drug resistance mutations in solid organ transplant recipients with suspected resistance using next generation sequencing. PLoS One. 2019; 14(7). DOI:10.1371/journal.pone.0219701.
Bouza E, Cobo J, Almirante B, Duenas C, Escudero R, Farinas C, et al. Recommendations from a panel of experts on the usefulness of fidaxomicin for the treatment of infections caused by Clostridium difficile. Rev Esp Quimioter. 2019; 32(1): 50-59
Fernandez Ruiz M, Gimenez E, Vinuesa V, Ruiz Merlo T, Parra P, Amat P, et al. Regular monitoring of cytomegalovirus-specific cell-mediated immunity in intermediate-risk kidney transplant recipients: predictive value of the immediate post-transplant assessment. Clin Microbiol Infect. 2019; 25(3). DOI:10.1016/j.cmi.2018.05.010.
Cozar A, Ramos Martinez A, Merino E, Martinez Garcia C, Shaw E, Marrodan T, et al. High delayed mortality after the first episode of Clostridium difficile infection. Anaerobe. 2019; 57: 93-98. DOI:10.1016/j.anaerobe.2019.04.004.
Hidalgo Tenorio C, Vinuesa D, Plata A, Davila PM, Iftimie S, Sequera S, et al. DALBACEN cohort: dalbavancin as consolidation therapy in patients with endocarditis and/or bloodstream infection produced by gram-positive cocci. Ann Clin Microbiol Antimicrob. 2019; 18(1): 30-30. DOI:10.1186/s12941-019-0329-6.
Lopez Soria L, Aguirrebengoa Ibarguren K, Raton Nieto JA, Barrios Andres JL. Skin lesion and lymphangitis in an immunocompetent patient. Enferm Infecc Microbiol Clin. 2019; 37(7): 481-482. DOI:10.1016/j.eimc.2018.12.012.
Mestres CA, Farinas MC, Munoz P, Goenaga MA, Kestler M, Martinez Selles M, et al. The ``Endocarditis Team'' of the Spanish Society of Cardiovascular Infections (SEICAV) reached 4500 cases collected prospectively. CIR CARDIOVASC. 2019; 26(5): 215-216. DOI:10.1016/j.circv.2019.07.002.
Cuervo G, Garcia Vidal C, Puig Asensio M, Merino P, Vena A, Martín Peña A, et al. Usefulness of guideline recommendations for prognosis in patients with candidemia. Med Mycol. 2019; 57(6): 659-667. DOI:10.1093/mmy/myy118.
Fernández Ruiz M, Cardozo C, Salavert M, Aguilar Guisado M, Escolà Vergé L, Muñoz P, et al. Candidemia in solid organ transplant recipients in Spain: Epidemiological trends and determinants of outcome. Transpl Infect Dis. 2019; 21(6). DOI:10.1111/tid.13195.
Requena S, Lozano AB, Caballero E, García F, Nieto MC, Téllez R, et al. Clinical experience with integrase inhibitors in HIV-2-infected individuals in Spain. J Antimicrob Chemother. 2019; 74(5): 1357-1362. DOI:10.1093/jac/dkz007.
Armiñanzas C, Fariñas Alvarez C, Martínez Sellés M, Miró Meda JM, Pericás JM, Ojeda Burgos G, et al. Role of age and comorbidities in mortality of patients with infective endocarditis. Eur J Intern Med. 2019; 64: 63-71. DOI:10.1016/j.ejim.2019.03.006.
Merchante N, Figueruela B, Rodríguez Fernández M, Rodríguez Arrondo F, Revollo B, Ibarra S, et al. Low performance of ultrasound surveillance for the diagnosis of hepatocellular carcinoma in HIV-infected patients. Aids. 2019; 33(2): 269-278. DOI:10.1097/QAD.0000000000002065.
Blanco Vidal MJ, López Soria L, Monzón de la Torre A, Montejo Baranda JM. Skin nodules in a liver transplant recipient. Enferm Infecc Microbiol Clin. 2018; 36(2): 140-141. DOI:10.1016/j.eimc.2016.09.009.
Rodríguez Arrondo F, von Wichmann MÁ, Camino X, Goenaga MÁ, Ibarguren M, Azcune H, et al. A case-control study of non-AIDS-defining cancers in a prospective cohort of HIV-infected patients. Med Clin. 2018; 150(8): 291-296. DOI:10.1016/j.medcli.2017.03.032.
Merchante N, Rodríguez Arrondo F, Revollo B, Merino E, Ibarra S, Galindo MJ, et al. Hepatocellular carcinoma after sustained virological response with interferon-free regimens in HIV/hepatitis C virus-coinfected patients. Aids. 2018; 32(11): 1423-1430. DOI:10.1097/QAD.0000000000001809.
Vicent L, Saldivar HG, Bouza E, Muñoz P, Cuerpo G, de Alarcón A, et al. Prognostic implications of a negative echocardiography in patients with infective endocarditis. Eur J Intern Med. 2018; 52: 40-48. DOI:10.1016/j.ejim.2018.01.033.
Zegri Reiriz I, de Alarcón A, Muñoz P, Martínez Sellés M, González Ramallo V, Miro JM, et al. Infective Endocarditis in Patients With Bicuspid Aortic Valve or Mitral Valve Prolapse. J Am Coll Cardiol. 2018; 71(24): 2731-2740. DOI:10.1016/j.jacc.2018.03.534.
Ramos Martínez A, Muñoz Serrano A, de Alarcón González A, Muñoz P, Fernández Cruz A, Valerio M, et al. Gentamicin may have no effect on mortality of staphylococcal prosthetic valve endocarditis. J Infect Chemother. 2018; 24(7): 555-562. DOI:10.1016/j.jiac.2018.03.003.
Kumar D, Ferreira VH, Blumberg E, Silveira F, Cordero E, Perez Romero P, et al. A 5-Year Prospective Multicenter Evaluation of Influenza Infection in Transplant Recipients. Clin Infect Dis. 2018; 67(9): 1322-1329. DOI:10.1093/cid/ciy294.
Aguado JM, Silva JT, Fernandez Ruiz M, Cordero E, Fortun J, Gudiol C, et al. Management of multidrug resistant Gram-negative bacilli infections in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations. Transplant Rev. 2018; 32(1): 36-57. DOI:10.1016/j.trre.2017.07.001.
Lopez Medrano F, Fernandez Ruiz M, Silva JT, Carver PL, van Delden C, Merino E, et al. Multinational case-control study of risk factors for the development of late invasive pulmonary aspergillosis following kidney transplantation. Clin Microbiol Infect. 2018; 24(2): 192-198. DOI:10.1016/j.cmi.2017.06.016.
Mensa J, Barberan J, Soriano A, Llinares P, Marco F, Canton R, et al. Antibiotic selection in the treatment of acute invasive infections by Pseudomonas aeruginosa: Guidelines by the Spanish Society of Chemotherapy. Rev Esp Quimioter. 2018; 31(1): 78-100
Pasquau J, Hidalgo Tenorio C, Montes ML, Romero Palacios A, Vergas J, Sanjoaquin I, et al. High quality of life, treatment tolerability, safety and efficacy in HIV patients switching from triple therapy to lopinavir/ritonavir monotherapy: A randomized clinical trial. PLoS One. 2018; 13(4). DOI:10.1371/journal.pone.0195068.
Aguado R, Paez Vega A, Aguera ML, Montejo M, Guirado L, Fortun J, et al. Lack of evidence of association between IFNG and IL28B polymorphisms and QuantiFERON-CMV test results in seropositive transplant patients. Hum Immunol. 2018; 79(6): 499-505. DOI:10.1016/j.humimm.2018.03.009.
Escola Verge L, Rodriguez Pardo D, Lora Tamayo J, Morata L, Murillo O, Vilchez H, et al. Candida periprosthetic joint infection: A rare and difficult-to-treat infection. J Infect. 2018; 77(2): 151-157. DOI:10.1016/j.jinf.2018.03.012.
Parra JA, Hernandez L, Munoz P, Blanco G, Rodriguez Alvarez R, Vilar DR, et al. Detection of spleen, kidney and liver infarcts by abdominal computed tomography does not affect the outcome in patients with left-side infective endocarditis. Medicine (Baltimore). 2018; 97(33). DOI:10.1097/MD.0000000000011952.
Cobo J, Merino E, Martinez C, Cozar Llisto A, Shaw E, Marrodan T, et al. Prediction of recurrent clostridium difficile infection at the bedside: the GEIH-CDI score. Int J Antimicrob Agents. 2018; 51(3): 393-398. DOI:10.1016/j.ijantimicag.2017.09.010.
Pericas JM, Moreno A, Almela M, Garcia Maria C, Marco F, Munoz P, et al. Efficacy and safety of fosfomycin plus imipenem versus vancomycin for complicated bacteraemia and endocarditis due to methicillin-resistant Staphylococcus aureus: a randomized clinical trial. Clin Microbiol Infect. 2018; 24(6): 673-676. DOI:10.1016/j.cmi.2018.01.010.
MONTEJO BARANDA JM. Usefulness of guideline recommendations for prognosis in patients with candidemia. Med Mycol. 2018. DOI:10.1093.
Cabezón I, Barreiro G, Egurbide MV. Parsonage-Turner syndrome: A case report. Reumatol Clin. 2017; 13(1): 60-61. DOI:10.1016/j.reuma.2016.03.001.
Gudiol C, Royo Cebrecos C, Tebe C, Abdala E, Akova M, Álvarez R, et al. Clinical efficacy of beta-lactam/beta-lactamase inhibitor combinations for the treatment of bloodstream infection due to extended-spectrum beta-lactamase-producing Enterobacteriaceae in haematological patients with neutropaenia: a study protocol for a retrospective observational study (BICAR). Bmj Open. 2017; 7(1). DOI:10.1136/bmjopen-2016-013268.
Lora Tamayo J, Senneville É, Ribera A, Bernard L, Dupon M, Zeller V, et al. The Not-So-Good Prognosis of Streptococcal Periprosthetic Joint Infection Managed by Implant Retention: The Results of a Large Multicenter Study. Clin Infect Dis. 2017; 64(12): 1742-1752. DOI:10.1093/cid/cix227.
Goenaga Sánchez MÁ, Kortajarena Urkola X, Bouza Santiago E, Muñoz García P, Verde Moreno E, Fariñas Álvarez MC, et al. Aetiology of renal failure in patients with infective endocarditis. The role of antibiotics. Med Clin. 2017; 149(8): 331-338. DOI:10.1016/j.medcli.2017.03.009.
Cantisan S, Paez Vega A, Santos F, Rodriguez Benot A, Aguado R, Rivero A, et al. Impact of age and cytomegalovirus on CD8(+) T-cell compartment remodeling after solid organ transplantation: A one-year follow-up study. Exp Gerontol. 2017; 95: 98-106. DOI:10.1016/j.exger.2017.04.011.
Gudiol C, Royo Cebrecos C, Abdala E, Akova M, Alvarez R, Maestro de La Calle G, et al. Efficacy of beta-Lactam/beta-Lactamase Inhibitor Combinations for the Treatment of Bloodstream Infection Due to Extended-Spectrum-beta-Lactamase-Producing Enterobacteriaceae in Hematological Patients with Neutropenia. Antimicrob Agents Chemother. 2017; 61(8). DOI:10.1128/AAC.00164-17.
Cuervo G, Garcia Vidal C, Puig Asensio M, Vena A, Meije Y, Fernandez Ruiz M, et al. Echinocandins Compared to Fluconazole for Candidemia of a Urinary Tract Source: A Propensity Score Analysis. Clin Infect Dis. 2017; 64(10): 1374-1379. DOI:10.1093/cid/cix033.
Lopez Aladid R, Guiu A, Sanclemente G, Lopez Medrano F, Cofan F, Mosquera MM, et al. Detection of cytomegalovirus drug resistance mutations in solid organ transplant recipients with suspected resistance. J Clin Virol. 2017; 90: 57-63. DOI:10.1016/j.jcv.2017.03.014.
Cortina TC, Carrion LG, Obieta JA, Baranda JMM. Recurrent frontal tumour in a patient with repeated craniotomies. Enferm Infecc Microbiol Clin. 2017; 35(4): 262-263. DOI:10.1016/j.eimc.2015.06.018.
Cordero E, Roca Oporto C, Bulnes Ramos A, Aydillo T, Gavalda J, Moreno A, et al. Two Doses of Inactivated Influenza Vaccine Improve Immune Response in Solid Organ Transplant Recipients: Results of TRANSGRIPE 1-2, a Randomized Controlled Clinical Trial. Clin Infect Dis. 2017; 64(7): 829-838. DOI:10.1093/cid/ciw855.
Ramos Martinez A, Vicente Lopez N, Sanchez Romero I, Padilla B, Merino Amador P, Garnacho Montero J, et al. Epidemiology and prognosis of candidaemia in elderly patients. Mycoses. 2017; 60(12): 808-817. DOI:10.1111/myc.12677.
Blanco Vidal MJ, Duenas Usategui M, Balerdi Malcorra A, Puente Pomposo M, Garcia Ruiz JC, Montejo Baranda JM. Piomyositis due to Escherichia coli in haematological patients, an increasing pathology. Rev Esp Quimioter. 2017; 30(3): 231-233
Blanco Vidal MJ, Guio Carrion L, Montejo Baranda JM, Iraurgu Arcarazo P. Neuroborreliosis: 10 years' experience in a tertiary hospital in the north of Spain. Rev Esp Quimioter. 2017; 30(3): 234-235
Wilcox MH, Gerding DN, Poxton IR, Kelly C, Nathan R, Birch T, et al. Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection. N Engl J Med. 2017; 376(4): 305-317. DOI:10.1056/NEJMoa1602615.
Fonollosa A, Martinez Indart L, Artaraz J, Martinez Berriotxoa A, Agirrebengoa K, Garcia M, et al. Clinical Manifestations and Outcomes of Syphilis-associated Uveitis in Northern Spain. Ocul Immunol Inflamm. 2016; 24(2): 147-152. DOI:10.3109/09273948.2014.943349.
Cuervo G, Gasch O, Shaw E, Camoez M, Domínguez MÁ, Padilla B, et al. Clinical characteristics, treatment and outcomes of MRSA bacteraemia in the elderly. J Infect. 2016; 72(3): 309-316. DOI:10.1016/j.jinf.2015.12.009.
Patiño Galindo JA, Thomson MM, Pérez Álvarez L, Delgado E, Cuevas MT, Fernández García A, et al. Transmission dynamics of HIV-1 subtype B in the Basque Country, Spain. Infect Genet Evol. 2016; 40: 91-97. DOI:10.1016/j.meegid.2016.02.028.
Fonollosa A, Llorenç V, Artaraz J, Jimenez B, Ruiz Arruza I, Agirrebengoa K, et al. SAFETY AND EFFICACY OF INTRAVITREAL DEXAMETHASONE IMPLANTS IN THE MANAGEMENT OF MACULAR EDEMA SECONDARY TO INFECTIOUS UVEITIS. Retin-J Retin Vitr Dis. 2016; 36(9): 1778-1785. DOI:10.1097/IAE.0000000000001001.
Lopez Medrano F, Silva JT, Fernandez Ruiz M, Carver PL, van Delden C, Merino E, et al. Risk Factors Associated With Early Invasive Pulmonary Aspergillosis in Kidney Transplant Recipients: Results From a Multinational Matched Case-Control Study. Am J Transplant. 2016; 16(7): 2148-2157. DOI:10.1111/ajt.13735.
Torre Cisneros J, Aguado JM, Gaston JJ, Almenar L, Alonso A, Cantisan S, et al. Management of cytomegalovirus infection in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations. Transplant Rev. 2016; 30(3): 119-143. DOI:10.1016/j.trre.2016.04.001.
Dominguez F, Ramos A, Bouza E, Munoz P, Valerio MC, Carmen Farinas M, et al. Infective endocarditis in hypertrophic cardiomyopathy: A multicenter, prospective, cohort study. Medicine (Baltimore). 2016; 95(26). DOI:10.1097/MD.0000000000004008.
Garcia Alvarez L, Mercedes Sanz M, Marin M, Farinas M, Montejo M, Goikoetxea J, et al. Tropheryma whipplei endocarditis in Spain: Case reports of 17 prospective cases. Medicine (Baltimore). 2016; 95(26). DOI:10.1097/MD.0000000000004058.
Benito N, Franco M, Ribera A, Soriano A, Rodriguez Pardo D, Sorlí L, et al. Time trends in the aetiology of prosthetic joint infections: a multicentre cohort study. Clin Microbiol Infect. 2016; 22(8): 7321-7328. DOI:10.1016/j.cmi.2016.05.004.
Fortun J, Muriel A, Martin Davila P, Montejo M, Len O, Torre Cisneros J, et al. Caspofungin versus fluconazole as prophylaxis of invasive fungal infection in high-risk liver transplantation recipients: A propensity score analysis. Liver Transplant. 2016; 22(4): 427-435. DOI:10.1002/lt.24391.
Perez Molina JA, Martinez Perez A, Serre N, Trevino B, Ruiz Giardin JM, Torrus D, et al. Characteristics of HIV infected individuals traveling abroad. Results from the plus REDIVI Collaborative Network. Enferm Infecc Microbiol Clin. 2016; 34(2): 108-113. DOI:10.1016/j.eimc.2015.03.023.
Lopez Medrano F, Fernandez Ruiz M, Silva JT, Carver PL, van Delden C, Merino E, et al. Clinical Presentation and Determinants of Mortality of Invasive Pulmonary Aspergillosis in Kidney Transplant Recipients: A Multinational Cohort Study. Am J Transplant. 2016; 16(11): 3220-3234. DOI:10.1111/ajt.13837.
von Wichmann MA, Portu J, Carrizo E, Ibarra S, Aguirrebengoa K, Gracia M, et al. Effectiveness and security of 3D/2D treatment in HCV/HIV coinfected cirrhotic patients. Hepatology. 2016; 64(1): 1003-1003
Gastaca M, Valdivieso A, Bustamante J, Fernandez JR, Ruiz P, Ventoso A, et al. Favorable longterm outcomes of liver transplant recipients treated de novo with once-daily tacrolimus: Results of a single-center cohort. Liver Transplant. 2016; 22(10): 1391-1400. DOI:10.1002/lt.24514.
Capdevila JA, Guembe M, Barberan J, de Alarcon A, Bouza E, Carmen Farinas M, et al. 2016 Expert consensus document on prevention, diagnosis and treatment of short-term peripheral venous catheter-related infections in adult. Rev Esp Quimioter. 2016; 29(4): 230-238
Cantisan S, Paez Vega A, Perez Romero P, Montejo M, Cordero E, Gracia Ahufinger I, et al. Prevention strategies differentially modulate the impact of cytomegalovirus replication on CD8(+) T-cell differentiation in high-risk solid organ transplant patients. Antiviral Res. 2016; 132: 244-251. DOI:10.1016/j.antiviral.2016.06.012.
Rivero A, Polo R, Lopez Aldeguer J, Lozano F, Antela A, Aguirrebengoa K, et al. Executive summary of the GESIDA/National AIDS Plan Consensus Document on Antiretroviral Therapy in Adults Infected by the Human Immunodeficiency Virus (Updated January 2016). Enferm Infecc Microbiol Clin. 2016; 34(7): 439-451. DOI:10.1016/j.eimc.2016.02.028.
Capdevila JA, Guembe M, Barberan J, de Alarcon A, Bouza E, Carmen Farinas M, et al. 2016 Expert consensus document on prevention, diagnosis and treatment of short-term peripheral venous catheter-related infections in adults. CIR CARDIOVASC. 2016; 23(4): 192-198. DOI:10.1016/j.circv.2016.06.001.
Dominguez Rodriguez F, Ramos A, Bouza E, Munoz P, Valerio MC, Farinas C, et al. Infective endocarditis in hypertrophic cardiomyopathy: should antibiotic prophylaxis be reconsidered?. Eur Heart J. 2016; 37(1): 1015-1015
Astigarraga I, Garcia Obregon S, Agirrebengoa K, Balerdi A, Carlos Garcia Ruiz J, Diaz B, et al. HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS COMPLICATING ADULT PATIENTS WITH HIV INFECTION. Pediatr Blood Cancer. 2015; 62(1): 2-2
Cantisan S, Rodelo Haad C, Paez Vega A, Nieto A, Vaquero JM, Poyato A, et al. Factors Related to the Development of CMV-Specific CD8+T cell Response in CMV-Seropositive Solid Organ Transplant Candidates. Am J Transplant. 2015; 15(3): 715-722. DOI:10.1111/ajt.13012.
Pedrol E, Caro Murillo AM, Castano MA, Riera M, Olalla J, Domingo P, et al. Renal safety of coformulated tenofovir/emtricitabine vs other nucleoside analogues in combination therapy in antiretroviral-naive patients aged 50 years or older in Spain: The TRIP study. HIV Clin Trials. 2015; 16(1): 43-48. DOI:10.1179/1528433614Z.0000000001.
Clemente W, Vidal E, Girao E, Ramos A, Govedic F, Merino E, et al. Risk factors, clinical features and outcomes of visceral leishmaniasis in solid-organ transplant recipients: a retrospective multicenter case-control study. Clin Microbiol Infect. 2015; 21(1): 89-95. DOI:10.1016/j.cmi.2014.09.002.
Carlos Garcia Ruiz J, Olazabal I, Adan Pedroso RM, Lopez Soria L, Velasco Benito V, Antonio Sanchez Aparicio J, et al. Disseminated fusariosis and hematologic malignancies, a still devastating association. Report of three new cases. Rev Iberoam Micol. 2015; 32(3): 190-196. DOI:10.1016/j.riam.2014.11.003.
Shaw E, Miro JM, Puig Asensio M, Pigrau C, Barcenilla F, Murillas J, et al. Daptomycin plus fosfomycin versus daptomycin monotherapy in treating MRSA: protocol of a multicentre, randomised, phase III trial. Bmj Open. 2015; 5(3). DOI:10.1136/bmjopen-2014-006723.
Berenguer J, Polo R, Lopez Aldeguer J, Lozano F, Aguirrebengoa K, Ramon Arribas J, et al. Executive summary of the GESIDA/National AIDS Plan Consensus Document on antiretroviral therapy in adults infected by the human immunodeficiency virus (updated January 2015). Enferm Infecc Microbiol Clin. 2015; 33(8): 544-556. DOI:10.1016/j.eimc.2015.03.017.
San Juan R, Navarro D, Garcia Reyne A, Montejo M, Munoz P, Carratala J, et al. Effect of long-term prophylaxis in the development of cytomegalovirus-specific T-cell immunity in D plus /R- solid organ transplant recipients. Transpl Infect Dis. 2015; 17(5): 637-646. DOI:10.1111/tid.12417.
Serre Delcor N, Martinez Perez A, Salvador F, Trevino Maruri B, Soriano Arandes A, Torrus Tendero D, et al. Eosinophilia, a common finding in international health. Trop Med Int Health. 2015; 20(1, SI): 391-391
Perez Romero P, Bulnes Ramos A, Torre Cisneros J, Gavalda J, Aydillo TA, Moreno A, et al. Influenza vaccination during the first 6 months after solid organ transplantation is efficacious and safe. Clin Microbiol Infect. 2015; 21(11). DOI:10.1016/j.cmi.2015.07.014.
Cuervo G, Camoez M, Shaw E, Angeles Dominguez M, Gasch O, Padilla B, et al. Methicillin-resistant Staphylococcus aureus (MRSA) catheter-related bacteraemia in haemodialysis patients. BMC Infect Dis. 2015; 15. DOI:10.1186/s12879-015-1227-y.
Garcia Gomez M, Guio L, Luis Hernandez J, Vilar B, Ignacio Pijoan J, Miguel Montejo J. Bacteraemia due to extended-spectrum beta-lactamases (ESBL) and other beta-lactamases (ampC and carbapenemase) producing Enterobacteriaceae: association with health-care and cancer. Rev Esp Quimioter. 2015; 28(5): 256-262
Torre Cisneros J, San Juan R, Rosso Fernandez CM, Tiago Silva J, Munoz Sanz A, Munoz P, et al. Tuberculosis Prophylaxis With Levofloxacin in Liver Transplant Patients Is Associated With a High Incidence of Tenosynovitis: Safety Analysis of a Multicenter Randomized Trial. Clin Infect Dis. 2015; 60(11): 1642-1649. DOI:10.1093/cid/civ156.
San Juan R, Navarro D, Garcia Reyne A, Montejo M, Munoz P, Carratala J, et al. Effect of delaying prophylaxis against CMV in D plus /R- solid organ transplant recipients in the development of CMV-specific cellular immunity and occurrence of late CMV disease. J Infect. 2015; 71(5): 561-570. DOI:10.1016/j.jinf.2015.06.013.
Ruiz Morales J, Ivanova Georgieva R, Fernández Hidalgo N, García Cabrera E, Miró JM, Muñoz P, et al. Left-sided infective endocarditis in patients with liver cirrhosis. J Infect. 2015; 71(6): 627-641. DOI:10.1016/j.jinf.2015.09.005.
de Egea V, Muñoz P, Valerio M, de Alarcón A, Lepe JA, Miró JM, et al. Characteristics and Outcome of Streptococcus pneumoniae Endocarditis in the XXI Century A Systematic Review of 111 Cases (2000-2013). Medicine (Baltimore). 2015; 94(39). DOI:10.1097/MD.0000000000001562.
Vega Y, Delgado E, Fernández García A, Cuevas MT, Thomson MM, Montero V, et al. Epidemiological Surveillance of HIV-1 Transmitted Drug Resistance in Spain in 2004-2012: Relevance of Transmission Clusters in the Propagation of Resistance Mutations. PLoS One. 2015; 10(5). DOI:10.1371/journal.pone.0125699.
Puig Asensio M, Ruiz Camps I, Fernández Ruiz M, Aguado JM, Muñoz P, Valerio M, et al. Epidemiology and outcome of candidaemia in patients with oncological and haematological malignancies: RESULTS from a population-based surveillance in Spain. Clin Microbiol Infect. 2015; 21(5): 4911-49110. DOI:10.1016/j.cmi.2014.12.027.
Valdivieso A, Prieto M, Bustamante J, Gastaca M, Ruiz P, Citores L, et al. Does an Early Liver Transplantation Influence the Prognosis of Hepatocellular Carcinoma?. Transplantation. 2015; 99(1): 163-163
Treviño A, Caballero E, de Mendoza C, Aguilera A, Pirón M, Soriano V, et al. The Burden of Neglected HIV-2 and HTLV-1 Infections in Spain. Aids Rev. 2015; 17(4): 212-219
González de Echavarri Perez de Heredia C, García Perez E, Bereciartua Bastarrica E, Martinez Fernandez G. Absceso de partes blandas, ¿es siempre lo que parece?. Med Clin. 2014; 142(2). DOI:10.1016/j.medcli.2013.05.021.
Fernández Valle T, Guío Carrión L, Galbarriatu Gutiérrez L, Vilar Achabal B. Actinomyces meyeri brain abscess. Med Clin. 2014; 143(7): 331-332. DOI:10.1016/j.medcli.2013.11.020.
Merchante N, Merino E, Rodriguez Arrondo F, Tural C, Munoz J, Delgado Fernandez M, et al. HIV/hepatitis C virus-coinfected patients who achieved sustained virological response are still at risk of developing hepatocellular carcinoma. Aids. 2014; 28(1): 41-47. DOI:10.1097/QAD.0000000000000005.
Perez Alvarez L, Delgado E, Vega Y, Montero V, Cuevas T, Fernandez Garcia A, et al. Predominance of CXCR4 tropism in HIV-1 CRF14_BG strains from newly diagnosed infections. J Antimicrob Chemother. 2014; 69(1): 246-253. DOI:10.1093/jac/dkt305.
Meije Y, Fortun J, Len O, Aguado JM, Moreno A, Cisneros JM, et al. Prevention strategies for cytomegalovirus disease and long-term outcomes in the high-risk transplant patient (D+/R-): experience from the RESITRA-REIPI cohort. Transpl Infect Dis. 2014; 16(3): 387-396. DOI:10.1111/tid.12226.
Fernandez Ruiz M, Maria Aguado J, Almirante B, Lora Pablos D, Padilla B, Puig Asensio M, et al. Initial Use of Echinocandins Does Not Negatively Influence Outcome in Candida parapsilosis Bloodstream Infection: A Propensity Score Analysis. Clin Infect Dis. 2014; 58(10): 1413-1421. DOI:10.1093/cid/ciu158.
Puig Asensio M, Padilla B, Garnacho Montero J, Zaragoza O, Aguado JM, Zaragoza R, et al. Epidemiology and predictive factors for early and late mortality in Candida bloodstream infections: a population-based surveillance in Spain. Clin Microbiol Infect. 2014; 20(4): 245-254. DOI:10.1111/1469-0691.12380.
Len O, Montejo M, Cervera C, Farinas MC, Sabe N, Ramos A, et al. Daptomycin is safe and effective for the treatment of gram-positive cocci infections in solid organ transplantation. Transpl Infect Dis. 2014; 16(4): 532-538. DOI:10.1111/tid.12232.
Martinez Selles M, Munoz P, Arnaiz A, Moreno M, Galvez J, Rodriguez Roda J, et al. Valve surgery in active infective endocarditis: A simple score to predict in-hospital prognosis. Int J Cardiol. 2014; 175(1): 133-137. DOI:10.1016/j.ijcard.2014.04.266.
Martinez Atienza J, Rosso Fernandez C, Roca C, Aydillo TA, Gavalda J, Moreno A, et al. Efficacy and safety of a booster dose of influenza vaccination in solid organ transplant recipients, TRANSGRIPE 1-2: study protocol for a multicenter, randomized, controlled clinical trial. Trials. 2014; 15. DOI:10.1186/1745-6215-15-338.
Trevino A, Soriano V, Poveda E, Parra P, Cabezas T, Caballero E, et al. HIV-2 viral tropism influences CD4+ T cell count regardless of viral load. J Antimicrob Chemother. 2014; 69(8): 2191-2194. DOI:10.1093/jac/dku119.
de Mendoza C, Caballero E, Aguilera A, Piron M, Ortiz de Lejarazu R, Rodriguez C, et al. HIV-2 and HTLV-1 Infections in Spain, a Non-Endemic Region. Aids Rev. 2014; 16(3): 152-159
Trevino A, Soriano V. Infections due to human immunodeficiency virus type 2 and human T-Iymphotropic viruses in Spain. Med Clin. 2014; 142(7): 323-326. DOI:10.1016/j.medcli.2013.06.009.
Rodriguez Pardo D, Pigrau C, Lora Tamayo J, Soriano A, del Toro MD, Cobo J, et al. Gram-negative prosthetic joint infection: outcome of a debridement, antibiotics and implant retention approach. A large multicentre study. Clin Microbiol Infect. 2014; 20(11): 911-919. DOI:10.1111/1469-0691.12649.
Gasch O, Camoez M, Dominguez MA, Padilla B, Pintado V, Almirante B, et al. Emergence of resistance to daptomycin in a cohort of patients with methicillin-resistant Staphylococcus aureus persistent bacteraemia treated with daptomycin. J Antimicrob Chemother. 2014; 69(2): 568-571. DOI:10.1093/jac/dkt396.
von Wichmann MA, Moreno A, Lopez Cortes LF, Ortega E, Mira JA, Quereda C, et al. Efficacy and safety of telaprevir based triple therapy in coinfected patients with advanced fibrosis. Final results of the spanish cohort. Hepatology. 2014; 60(1, SI): 669-670
Rodriguez Alvarez R, Goikoetxea J, Garcia M, Figueras Y, Hernandez L, Montejo M. Endovascular infections by Campylobacter: with regard to two cases. Rev Esp Quimioter. 2014; 27(2): 127-129
Valdivieso A, Martinez Indart L, Prieto M, Gastaca M, Ventoso A, Ruiz P, et al. Risk Factors of Late Arterial Complications in Liver Transplantation. Liver Transplant. 2014; 20(1): 220-220
Valdivieso A, Martinez Indart L, Prieto M, Gastaca M, Ruiz P, Ventoso A, et al. Risk Factors of Early Arterial Complications in Liver Transplantation. Liver Transplant. 2014; 20(1): 293-293
Sun H, Munoz P, Torre Cisneros J, Aguado JM, Lattes R, Montejo M, et al. Tuberculosis in solid-organ transplant recipients: disease characteristics and outcomes in the current era. Prog Transplant. 2014; 24(1): 37-43. DOI:10.7182/pit2014398.
Aguirrebengoa K. Desafíos de lopinavir/ritonavir en la cronicidad de la infección por virus de la inmunodeficiencia humana. Enferm Infecc Microbiol Clin. 2014; 32 Suppl 3: 26-30. DOI:10.1016/S0213-005X(14)70165-X.
Puig Asensio M, Peman J, Zaragoza R, Garnacho Montero J, Martin Mazuelos E, Cuenca Estrella M, et al. Impact of Therapeutic Strategies on the Prognosis of Candidemia in the ICU. Crit Care Med. 2014; 42(6): 1423-1432. DOI:10.1097/CCM.0000000000000221.
Guinea J, Zaragoza O, Escribano P, Martin Mazuelos E, Peman J, Sanchez Reus F, et al. Molecular Identification and Antifungal Susceptibility of Yeast Isolates Causing Fungemia Collected in a Population-Based Study in Spain in 2010 and 2011. Antimicrob Agents Chemother. 2014; 58(3): 1529-1537. DOI:10.1128/AAC.02155-13.
Domingo P, Polo R, Lozano F, López Aldeguer J, Aguirrebengoa K, Estrada V, et al; Panel of Experts of GESIDA and Spanish Secretariat for the National Plan on AIDS. Executive summary of the Consensus Document of GeSIDA and Spanish Secretariat for the National Plan on AIDS on combined antiretroviral treatment in adults infected by the human immunodeficiency virus (January 2013). Enferm Infec Microbiol Clin. 2013;31:604-13. FI: 1,478(Q4)
López-Cortés LE, Del Toro MD, Gálvez-Acebal J, Bereciartua-Bastarrica E, Fariñas MC, Sanz-Franco M, et al; REIPI/SAB group. Impact of an Evidence-Based Bundle Intervention in the Quality-of-Care Management and Outcome of Staphylococcus aureus Bacteremia. Clin Infect Dis. 2013;57:1225-33. FI: 9,374(Q1)
Rodríguez-Sainz A, Escalza-Cortina I, Guio-Carrión L, Matute-Nieves A, Gómez-Beldarrain M, Carbayo-Lozano G, et al. Intracerebral hematoma complicating herpes simplex encephalitis. Clin Neurol Neurosurg. 2013;115:2041-5. FI: 1,234(Q3)
Cisneros JM, Cobo J, San Juan R, Montejo M, Fariñas MC. Education on antibiotic use. Education systems and activities that work. Enferm Infecc Microbiol Clin. 2013;31(Suppl 4):31-7. FI: 1,478(Q4)
Blanco JR, Caro-Murillo AM, Castaño MA, Olalla J, Domingo P, Arazo P, et al. Safety, Efficacy, and Persistence of Emtricitabine/Tenofovir Versus Other Nucleoside Analogues in Naive Subjects Aged 50 Years or Older in Spain: The TRIP Study. HIV Clin Trials 2013;14:204-5. FI: 2,304(Q2)
González de Echavarri Perez de Heredia C, García Perez E, Bereciartua Bastarrica E, Martinez Fernandez G. Absceso de partes blandas, ¿es siempre lo que parece?. Med Clin. 2013. : -0. FI: 1,399(Q2)
Gasch O, Camoez M, Domínguez MA, Padilla B, Pintado V, Almirante B, et al. Predictive factors for early mortality among patients with methicillin-resistant Staphylococcus aureus bacteraemia. J Antimicrob Chemother. 2013;68:1423-30. FI: 5,338(Q1)
Montejo M, Goikoetxea J, Mularoni A, Blanco MJ, Gaafar A, Boado MV, et al; Grupo GAMES. Tropheryma wipplei endocarditis: A report of 3 cases. Rev Esp Quim. 2013;26:168-70. FI: 0,836(Q4)
Sun HY, Munoz P, Torre-Cisneros J, Aguado JM, Lattes R, Montejo M, et al. Mycobacterium Tuberculosis-Associated Immune Reconstitution Syndrome in Solid-Organ Transplant Recipients. Transplantation. 2013;95:1173-81. FI: 3,781(Q1)
Fernández-Hidalgo N, Almirante B, Gavaldà J, Gurgui M, Peña C, de Alarcón A, et al. Ampicillin Plus Ceftriaxone Is as Effective as Ampicillin Plus Gentamicin for Treating Enterococcus faecalis Infective Endocarditis. Clin Infect Dis. 2013;56:1261-8. FI: 9,374(Q1)
Blanco-Vidal MJ, Catalan-Urribarrena G, Lopez JI, del Aguila C, Magnet A, Pomposo-Gaztelu I, et al. Left-sided hemiparesis in a diabetic patient: chronic granulomatous encephalitis due to Acanthamoeba. Rev Neurol. 2013;56:187-8. FI: 1,179(Q4)
López-Soria LM, Bereciartua E, Santamaría M, Soria LM, Hernández-Almaraz JL, Mularoni A, et al. First case report of catheter-related fungemia by Candida nivariensis in the Iberian Peninsula. Rev Iberoam Micol. 2013;30:69-71. FI: 1,312(Q3)
Mensa J, Soriano A, Llinares P, Barberán J, Montejo M, Salavert M, et al. Guía de tratamiento antimicrobiano de la infección por Staphylococcus aureus. Rev Esp Quimioter. 2013;26(Suppl 1):1-84. FI: 0,836(Q4)
Gonzalez-Padilla M, Caston JJ, Vidal E, Arizon JM, Segura C, Montejo M, et al. Epidemiology and clinical impact of infection in patients awaiting heart transplantation. Int J Infect Dis. 2013;17:681-5. FI: 2,357(Q3).
Cantisan S, Lara R, Montejo M, Redel J, Rodriguez-Benot A, Gutierrez-Aroca J, et al. Pretransplant Interferon- Secretion by CMV-Specific CD8+T Cells Informs the Risk of CMV Replication After Transplantation. Am J Transplant. 2013;13:738-45. FI: 6,192(Q1)
Cantisan S, Torre-Cisneros J, Lara R, Zarraga S, Montejo M, Solana R. Impact of Cytomegalovirus on Early Immunosenescence of CD8+ T Lymphocytes After Solid Organ Transplantation. J Gerontol Ser A-Biol Sci Med Sci. 2013;68:1-5. FI: 4,314(Q1)
