Investigación en genética y control de diabetes y enfermedades endocrinas

Olazagoitia Garmendia A, Rojas Marquez H, Sebastian delaCruz M, Agirre Lizaso A, Ochoa A, Mendoza Gomez LM, et al. m⁶A Methylated Long Noncoding RNA LOC339803 Regulates Intestinal Inflammatory Response. Adv Sci (Weinh). 2024; 11(13): 2307928-2307928. DOI:10.1002/advs.202307928.

Montero E, Bujaldon R, Montanya E, Calle Pascual AL, Rojo Martinez G, Castano L, et al. Cross-sectional association between severe periodontitis and diabetes mellitus: A nation-wide cohort study. J Clin Periodontol. 2024; 51(4): 368-379. DOI:10.1111/jcpe.13937.

de Frutos F, Diez Lopez C, Garcia Romero E, Gondra L, Madariaga L, Ariceta G, et al. Dilated Cardiomyopathy With Concomitant Salt-Losing Renal Tubulopathy Caused by Heterozygous RRAGD Gene Variant. Circ-Genom Precis Med. 2024; 17(2): 4336-4336. DOI:10.1161/CIRCGEN.123.004336.

Balague Dobon L, Esko T, de Heredia ML, Abellan J, Acosta Isaac R, Maria Aguado J, et al. Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2. Commun Biol. 2024; 7(1). DOI:10.1038/s42003-024-05805-6.

Villar Taibo R, Galdon Sanz Pastor A, Fernandez Rubio E, Barajas Galindo D, Simo Servat A, Ampudia Blasco FJ. Are New Ultra-Rapid-Acting Insulins Associated with Improved Glycemic Control and Reduced Hypoglycemia in Comparison to Conventional Rapid-Acting Insulins for Individuals with Type 1 and Type 2 Diabetes? A Systematic Review and Meta-Analysis. Diabetes Technol Ther. 2024; 26(8): 575-586. DOI:10.1089/dia.2023.0524.

Araujo Castro M, Biagetti B, Torre EM, Novoa Testa I, Cordido F, Corrales EP, et al. Differences Between GH- and PRL-Cosecreting and GH-Secreting Pituitary Adenomas: a Series of 604 Cases. J Clin Endocrinol Metab. 2024. DOI:10.1210/clinem/dgae126.

Díez JJ, Anda E, Pérez Corral B, Paja M, Alcázar V, Sánchez Ragnarsson C, et al. Incident comorbidities in patients with chronic hypoparathyroidism after thyroidectomy: a multicenter nationwide study. Front Endocrinol. 2024; 15. DOI:10.3389/fendo.2024.1348971.

Perez A, Courel Del Rio V, Garcia Fernandez S, Castano Gonzalez L, Riano Galan I. Hypomagnesemia, a diagnosis to consider. An Pediatr (Engl Ed). 2024; 100(4): 292-293. DOI:10.1016/j.anpede.2024.01.018.

Kouri C, Sommer G, Lapiscina IMD, Elzenaty RN, Tack LJW, Cools M, et al. Clinical and genetic characteristics of a large international cohort of individuals with rare NR5A1/SF-1 variants of sex development. Ebiomedicine. 2024; 99. DOI:10.1016/j.ebiom.2023.104941.

Velazquez MNR, Blanco F, Ayala Lugo A, Franco L, Jolly V, Di Tore D, et al. A Novel Mutation in the INSR Gene Causes Severe Insulin Resistance and Rabson-Mendenhall Syndrome in a Paraguayan Patient. Int J Mol Sci. 2024; 25(6). DOI:10.3390/ijms25063143.

García Castaño A, Madariaga L, Gómez Conde S, González P, Grau G, Rica I, et al. Genetic profile of a large Spanish cohort with hypercalcemia. Front Endocrinol. 2024; 15. DOI:10.3389/fendo.2024.1297614.

Perez Lopez P, Bahillo Curieses P, Fernández P, Martínez R, Delgado E, Ortolá A, et al. Clinical, glycometric features and treatment in a family with monogenic diabetes due to a new mutation in the insulin gene. Endocrinol Diabetes Nutr. 2024; 71(2): 77-82. DOI:10.1016/j.endien.2024.03.006.

Naamneh Elzenaty R, Martinez de LaPiscina I, Kouri C, Sauter K, Sommer G, Castano L, et al. Characterization of 35 Novel NR5A1/SF-1 Variants Identified in Individuals With Atypical Sexual Development: The SF1next Study. J Clin Endocrinol Metab. 2024. DOI:10.1210/clinem/dgae251.

Ampuero J, Aller R, Gallego Durán R, Crespo J, Calleja JL, García Monzón C, et al. The biochemical pattern defines MASLD phenotypes linked to distinct histology and prognosis. J Gastroenterol. 2024; 59(7): 586-597. DOI:10.1007/s00535-024-02098-8.

Sampedro Nunez M, Herrera Martinez AD, Ibanez Costa A, Rivero Cortes E, Venegas E, Robledo M, et al. Integrative clinical, hormonal, and molecular data associate with invasiveness in acromegaly: REMAH study. Eur J Endocrinol. 2024; 190(6): 421-433. DOI:10.1093/ejendo/lvae045.

Tapias EA, Miles DM, Albillos A, Aller R, Ampuero J, Andrade RJ, et al. Proceedings of the 5th Meeting of Translational Hepatology, organized by the Spanish Association for the Study of the Liver (AEEH). Gastroenterol Hepatol. 2024; 47(10): 502207-502207. DOI:10.1016/j.gastrohep.2024.502207.

Araujo Castro M, Parra P, Rojas Marcos PM, Fano MP, Boillos M, Pascual Corrales E, et al. Differences in the clinical and hormonal presentation of patients with familial and sporadic primary aldosteronism. Front Endocrinol. 2024; 15. DOI:10.3389/fendo.2024.1336306.

Biagetti B, Araujo Castro M, Menendez Torre E, Novoa Testa I, Cordido F, Pascual Corrales E, et al. Effectiveness of combined first-line medical treatment in acromegaly with prolactin cosecretion. Eur J Endocrinol. 2024; 190(6): 458-466. DOI:10.1093/ejendo/lvae053.

Araujo Castro M, Biagetti B, Menedez Torre E, Novoa Testa I, Cordido F, Pascual Corrales E, et al. Pegvisomant and pasireotide in PRL and GH co-secreting vs GH-secreting Pit-NETs. Endocrine-Related Cancer. 2024; 31(7). DOI:10.1530/ERC-24-0043.

Cardona Hernandez R, Castano Gonzalez LA, Atance EP, Echevarria IR. Advancing toward the aetiologic treatment of type 1 diabetes in the early stages: the dawn of a new era in its management. An Pediatr (Engl Ed). 2024. DOI:10.1016/j.anpede.2024.03.051.

Gomez Munoz L, Perna Barrull D, Caroz Armayones JM, Murillo M, Rodriguez Fernandez S, Valls A, et al. Candidate biomarkers for the prediction and monitoring of partial remission in pediatric type 1 diabetes (vol 13, 825426, 2022). Front Immunol. 2024; 15. DOI:10.3389/fimmu.2024.1439643.

Pascual Corrales E, Biagetti B, Marazuela M, Asensio Wandosel D, Berrocal VR, Echarri AI, et al. Glucose metabolism outcomes after pituitary surgery in patients with acromegaly. Pituitary. 2024; 27(5): 497-506. DOI:10.1007/s11102-024-01415-x.

Menendez Torre EL, Gutierrez Hurtado A, Ollero MD, Irigaray A, Martin P, Parra P, et al. Natural history and surgical outcomes of Rathke's cleft cysts: a Spanish multicenter study. Front Endocrinol. 2024; 15. DOI:10.3389/fendo.2024.1413810.

Gil Pitarch C, Serrano Macia M, Simon J, Mosca L, Conter C, Rejano Gordillo CM, et al. Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway. Cell Rep Med. 2024; 5(7): 101653-101653. DOI:10.1016/j.xcrm.2024.101653.

Araujo Castro M, Ruiz Sanchez JG, Gonzalvo C, Lamas C, Parra Ramirez P, Martin Marcos Rojas P, et al. Genetic testing for primary aldosteronism in SPAIN: Results from the SPAIN-ALDO Registry and review of the literature. J Clin Endocrinol Metab. 2024. DOI:10.1210/clinem/dgae523.

Araujo Castro M, Paja Fano M, Gonzalez Boillos M, Pascual Corrales E, Martin Rojas Marcos P, Garcia Cano A, et al. Impact of primary aldosteronism on kidney function: results from the SPAIN-ALDO registry. J Hypertens. 2024; 42(10): 1805-1812. DOI:10.1097/HJH.0000000000003813.

Saliba Gustafsson P, Justesen JM, Ranta A, Sharma D, Bielczyk Maczynska E, Li J, et al. A functional genomic framework to elucidate novel causal metabolic dysfunction-associated fatty liver disease genes. Hepatology. 2024. DOI:10.1097/HEP.0000000000001066.

Pérez A, del Río VC, Fernández SG, González LC, Galán IR. Hypomagnesemia, a diagnosis to consider. An Pediatr. 2024; 100(4)

Urrutia I, Martinez R, Calvo B, Marcelo I, Saso Jimenez L, de Lapiscina IM, et al. Risk for progression to type 1 diabetes in first-degree relatives under 50 years of age. Front Endocrinol. 2024; 15. DOI:10.3389/fendo.2024.1411686.

García Pérez J, Borobia AM, Pérez Olmeda M, Portolés A, Castano L, Campins Arti M, et al. Immunogenicity of a third dose with mRNA-vaccines in the ChAdOx1-S/BNT162b2 vaccination SARS-CoV-2 variants. iScience. 2024; 27(9): 110728-110728. DOI:10.1016/j.isci.2024.110728.

Naamneh Elzenaty R, Kouri C, Martinez de Lapiscina I, Sauter K, Moreno F, Camats Tarruella N, et al. NR5A1/SF-1 Collaborates with Inhibin a and the Androgen Receptor. Int J Mol Sci. 2024; 25(18). DOI:10.3390/ijms251810109.

Diz de Almeida S, Cruz R, Luchessi AD, Lorenzo Salazar JM, de Heredia ML, Quintela I, et al. Novel risk loci for COVID-19 hospitalization among admixed American populations. ELIFE. 2024; 13. DOI:10.7554/eLife.93666.

Gomez Peralta F, Valledor X, Abreu C, Fernandez Rubio E, Cotovad L, Pujante P, et al. Nocturnal Glucose Profile According to Timing of Dinner Rapid Insulin and Basal and Rapid Insulin Type: An Insulclock® Connected Insulin Cap-Based Real-World Study. Biomedicines. 2024; 12(7). DOI:10.3390/biomedicines12071600.

Díez JJ, Anda E, Pérez Corral B, Paja M, Alcazar V, Sánchez Ragnarsson C, et al. Prevalence of chronic postsurgical hypoparathyroidism not adequately controlled: an analysis of a nationwide cohort of 337 patients. Front Endocrinol. 2024; 15. DOI:10.3389/fendo.2024.1464515.

Fernandez Ramos C, Arana Arri E, Vela A, Urrutia I, Santos Zorrozua B, Rica I. Increased incidence of pediatric type 1 diabetes during the pandemic in Biscay, Spain. Endocrinol Diabetes Nutr. 2024; 71(8): 332-339. DOI:10.1016/j.endien.2024.09.002.

Rada P, Carceller Lopez E, Hitos AB, Gomez Santos B, Fernandez Hernandez C, Rey E, et al. Protein kinase D2 modulates hepatic insulin sensitivity in male mice. Mol Metab. 2024; 90: 102045-102045. DOI:10.1016/j.molmet.2024.102045.

Lluch A, Latorre J, Oliveras Canellas N, Fernandez Sanchez A, Moreno Navarrete JM, Castells Nobau A, et al. A novel long non-coding RNA connects obesity to impaired adipocyte function. Mol Metab. 2024; 90: 102040-102040. DOI:10.1016/j.molmet.2024.102040.

Coombes JD, Manka PP, Swiderska Syn M, Vannan DT, Riva A, Claridge LC, et al. Osteopontin Promotes Cholangiocyte Secretion of Chemokines to Support Macrophage Recruitment and Fibrosis in MASH. Liver Int. 2024. DOI:10.1111/liv.16131.

Zouridis S, Nasir AB, Aspichueta P, Syn W. The Link between Metabolic Syndrome and the Brain. Digestion. 2024: 1-9. DOI:10.1159/000541696.

Biagetti B, Asanza EC, Pérez López C, Araujo Castro M, Camara R, Guerrero Pérez F, et al. Pituitary Apoplexy: Comorbidities, Management, and Outcomes-A Spanish Observational Multicenter Study. J Clin Endocrinol Metab. 2024. DOI:10.1210/clinem/dgae649.

Lamas C, Febrero B, Casteras A, Romero Lluch A, Recio Cordova JM, Ros I, et al. Current Management of Head and Neck Paragangliomas: A Multicenter Series With Long-Term Follow-Up. Otolaryngol Head Neck Surg. 2024. DOI:10.1002/ohn.1012.

Fernández Ramos C, Arana Arri E, Vela A, Urrutia I, Zorrozua BS, Rica I. Increased incidence of pediatric type 1 diabetes during the pandemic in Biscay, Spain. Endocrinol Diabetes Nutr. 2024; 71(8): 332-339. DOI:10.1016/j.endinu.2024.05.006.

Valdes N, Romero A, Diego E, Calatayud M, Lamas C, Araujo Castro M, et al. Long term outcomes of pituitary adenomas in Multiple Endocrine Neoplasia type 1: a nationwide study. Front Endocrinol. 2024; 15. DOI:10.3389/fendo.2024.1427821.

Lago Sampedro A, Oualla Bachiri W, García Serrano S, Maldonado Araque C, Valdés S, Doulatram Gamgaram V, et al. Protective Effect of High Adherence to Mediterranean Diet on the Risk of Incident Type-2 Diabetes in Subjects with MAFLD: The Di@bet.es Study. Nutrients. 2024; 16(21). DOI:10.3390/nu16213788.

Schmitt L, Krings KS, Wolsing A, Buque X, Zimmermann M, Flores Romero H, et al. Targeting mitochondrial metabolism by the mitotoxin bromoxib in leukemia and lymphoma cells. Cell Commun Signal. 2024; 22(1). DOI:10.1186/s12964-024-01913-2.

Sánchez E, Elghazally NM, El Sallamy RM, Ciudin A, Sánchez Bao A, Hashish MS, et al. Discrimination and Stigma Associated with Obesity: A Comparative Study between Spain and Egypt - Data from the OBESTIGMA study. Obes Facts. 2024; 17(6): 582-592. DOI:10.1159/000540635.

de Lapiscina IM, Diego E, Baquero C, Fernandez E, Menendez E, Moure MD, et al. Novel Gene Variants in a Nationwide Cohort of Patients with Pheochromocytoma and Paraganglioma. Int J Mol Sci. 2024; 25(22). DOI:10.3390/ijms252212056.

Biagetti B, Cordero Asanza E, Garcia Feijoo P, Araujo Castro M, Rodriguez Berrocal V, Serra G, et al. Trends and Outcomes in Pituitary Apoplexy Management: A Spanish Observational Multicenter Study. Neurosurgery. 2024. DOI:10.1227/neu.0000000000003281.

Valdecantos MP, Ruiz L, Folgueira C, Rada P, Gomez Santos B, Solas M, et al. The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk. Nat Commun. 2024; 15(1). DOI:10.1038/s41467-024-54080-w.

Araujo Castro M, Fano MP, Gonzalez Boillos M, Pascual Corrales E, Ramirez PP, Rojas Marcos PM, et al. Influence of smoking on cardiometabolic profile and surgical outcomes in patients with primary aldosteronism: a cohort study. Eur J Endocrinol. 2024; 191(6): 579-587. DOI:10.1093/ejendo/lvae143.

Corripio R, Soriano Guillén L, Herrero FJ, Castro Feijoó L, Escribano A, Sol Ventura P, et al. Adult height in girls with idiopathic central precocious puberty treated with triptorelin. Front Endocrinol. 2024; 15. DOI:10.3389/fendo.2024.1498726.

Gonzalez Fernandez P, Grau Bolado G, Fernandez Lopez C, Ponce de Leon Saenz de Navarrete S, Guadilla Fernandez ML, Vazquez San Miguel F, et al. Changing trends in transgender demographics and morbidity: baseline data from a Spanish cohort. Sex Health. 2023; 20(1): 96-98. DOI:10.1071/SH22171.

Gonzalez Moro I, Rojas Marquez H, Sebastian delaCruz M, Mentxaka Salgado J, Olazagoitia Garmendia A, Mendoza LM, et al. A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells. Front Endocrinol. 2023; 14: 1101934-1101934. DOI:10.3389/fendo.2023.1101934.

Biagetti B, Iglesias P, Villar Taibo R, Moure M, Paja M, Araujo Castro M, et al. Mortality in acromegaly diagnosed in the elderly in Spain is higher in women compared to the general Spanish population. J Clin Endocrinol Metab. 2023. DOI:10.1210/clinem/dgad141.

Lavin B, Eykyn TR, Phinikaridou A, Xavier A, Kumar S, Buqué X, et al. Characterization of hepatic fatty acids using magnetic resonance spectroscopy for the assessment of treatment response to metformin in an eNOS^-/- mouse model of metabolic nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. NMR Biomed. 2023; 36(8): 4932-4932. DOI:10.1002/nbm.4932.

Perez Fernandez L, Sastre J, Zafon C, Oleaga A, Castelblanco E, Capel I, et al. Validation of dynamic risk stratification and impact of BRAF in risk assessment of thyroid cancer, a nation-wide multicenter study. Front Endocrinol. 2023; 13. DOI:10.3389/fendo.2022.1071775.

Hirschler V, Gonzalez C, Rica I, Lapertosa S, Urrutia I, Martinez Salazar R, et al. Hepcidin is associated directly with inflammatory markers and inversely with glucose in Indigenous Argentinean children. Horm Res Paediatr. 2023; 96(SUPPL 2): 32-33

Contreras A, Pino C, Garcia H, Loureiro C, Castano L. Severe craneosynostosis in non-autoimmune neonatal hyperthyroidism, suspected tshr activating mutation, a case report. Horm Res Paediatr. 2023; 96(SUPPL 2): 142-142

Martinez de lapiscina I, Kouri C, Aurrekoetxea J, Sanchez M, Naamneh R, Sommer G, et al. Uncovering the role of the SF-1/NR5A1 p.Gly146Ala variant for the phenotype of DSD patients. Horm Res Paediatr. 2023; 96(SUPPL 2): 39-39

Kouri C, Sommer G, De Lapiscina IM, Tack L, Cools M, Flück CE, et al. Birth weight and height in individuals with SF-1/ NR5A1 variants: Results from the international SF1next study. Horm Res Paediatr. 2023; 96(SUPPL 2): 129-129

Elzenaty RN, De Lapiscina IM, Kouri C, Sommer G, Fluck CE. Pathogenicity testing of fifteen novel missense SF-1/NR5A1 variants in DSD patients. Horm Res Paediatr. 2023; 96(SUPPL 2): 136-136

Valassi E, Manichanh C, Amodru V, Fernandez PG, Gaztambide S, Yanez F, et al. Gut microbial dysbiosis in patients with Cushing's disease in long-term remission. Relationship with cardiometabolic risk. Front Endocrinol. 2023; 14. DOI:10.3389/fendo.2023.1074757.

Gonzalez Moro I, Garcia Etxebarria K, Mendoza LM, Fernandez Jimenez N, Mentxaka J, Olazagoitia Garmendia A, et al. LncRNA ARGI Contributes to Virus-Induced Pancreatic ß Cell Inflammation Through Transcriptional Activation of IFN-Stimulated Genes. Adv Sci. 2023; 10(25). DOI:10.1002/advs.202300063.

Urrutia I, Martinez R, Calvo B, Saso Jimenez L, Gonzalez P, Fernandez Rubio E, et al. Autoimmune Diabetes From Chilhood to Adulthood: The Role of Pancreatic Autoantibodies and HLA-DRB1 Genotype. J Clin Endocrinol Metab. 2023. DOI:10.1210/clinem/dgad277.

Ruiz Garcia I, Sanchez Torralvo FJ, Gomez Zumaquero JM, Colomo Rodriguez N, Dominguez Lopez M, Saso Jimenez L, et al. SHORT syndrome: A good case can break an old acronym. Endocrinol Diabetes Nutr. 2023; 70(3): 220-222. DOI:10.1016/j.endinu.2022.11.009.

Alonso Rubio P, Bahillo Curieses MP, Prieto Matos P, Bertholt Zuber ML, Martin Alonso MM, Murillo Valles M, et al. Adaptation, reliability and validity of health-related quality of life questionnaires: Disabkids chronic and specific diabetes disease in children and adolescents with diabetes mellitus type 1. Endocrinol Diabetes Nutr. 2023; 70 Suppl 3: 18-26. DOI:10.1016/j.endien.2023.07.004.

Capelo Diz A, Lachiondo Ortega S, Fernández Ramos D, Canas Martin J, Goikoetxea Usandizaga N, Serrano Maciá M, et al. Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting. Cell Metab. 2023; 35(8). DOI:10.1016/j.cmet.2023.07.002.

Sainz de Los Terreros Errea A, Madariaga L, Garcia Castano A. Hypercalcemia in patients with mutations in NR3C2 and SCNN1B. Med Clin. 2023; 161(10). DOI:10.1016/j.medcli.2023.06.041.

Garcia Castano A, Gomez Conde S, Gondra L, Herrero M, Aguirre M, de la Hoz A, et al. Genotypic variability in patients with clinical diagnosis of Bartter syndrome type 3. Sci Rep. 2023; 13(1). DOI:10.1038/s41598-023-38179-6.

Marsal Beltran A, Rodríguez Castellano A, Astiarraga B, Calvo E, Rada P, Madeira A, et al. Protective effects of the succinate/SUCNR1 axis on damaged hepatocytes in NAFLD. Metab-Clin Exp. 2023; 145. DOI:10.1016/j.metabol.2023.155630.

Noureddin M, Truong E, Mayo R, Martinez Arranz I, Minchole I, Banales JM, et al. Serum identification of At-Risk MASH: The Metabolomics-Advanced steatohepatitis fibrosis score (MASEF). Hepatology. 2023; 79(1): 135-148. DOI:10.1097/HEP.0000000000000542.

Martinez de LaPiscina I, Kouri C, Aurrekoetxea J, Sanchez M, Naamneh Elzenaty R, Sauter K, et al. Genetic reanalysis of patients with a difference of sex development carrying the NR5A1/SF-1 variant p.Gly146Ala has discovered other likely disease-causing variations. PLoS One. 2023; 18(7). DOI:10.1371/journal.pone.0287515.

Aurrekoetxea I, Gomez Santos B, Apodaka Biguri M, Ruiz de Gauna M, Gonzalez Romero F, Buque X, et al. In Vivo Tissue Lipid Uptake in Antisense Oligonucleotide (ASO)-Treated Mice. Methods Mol Biol. 2023; 2675: 1-13. DOI:10.1007/978-1-0716-3247-5_1.

Gomez Santos B, Saenz de Urturi D, Buque X, Aurrekoetxea I, Nieva A, Fernandez Puertas I, et al. In Vivo Hepatic Triglyceride Secretion Rate in Antisense Oligonucleotide (ASO)-Treated Mice. Methods Mol Biol. 2023; 2675: 15-26. DOI:10.1007/978-1-0716-3247-5_2.

Mendoza Gomez LM, Sebastian delaCruz M, Olazagoitia Garmendia A, Gonzalez Moro I, Rojas Marquez H, Mentxaka J, et al. Preparation of pepsin trypsin digested gliadin for stimulation experiments. METHOD CELL BIOL. 2023; 179: 195-201. DOI:10.1016/bs.mcb.2022.11.005.

Gomez Peralta F, Menendez E, Conde S, Conget I, Novials A, Olmedo IS, et al. Physical activity patterns in type 1 diabetes in Spain: The SED1 study. BMC Sports Sci Med Rehabil. 2023; 15(1). DOI:10.1186/s13102-023-00695-3.

Santamaria J, Breton I, Fernandez A, Hanzu F, Luque R, Pines P, et al. RECALSEEN 2021. Resources and quality in the Endocrinology and Nutrition units of the National Health System of Spain. Endocrinol Diabetes Nutr. 2023; 70(7): 459-467. DOI:10.1016/j.endien.2023.03.022.

Valdes S, Doulatram Gamgaram V, Maldonado Araque C, Garcia Escobar E, Garcia Serrano S, Oualla Bachiri W, et al. Association between exposure to air pollution and blood lipids in the general population of Spain. Eur J Clin Invest. 2023: 14101-14101. DOI:10.1111/eci.14101.

Gomez Peralta F, Valledor X, Lopez Picado A, Abreu C, Fernandez Rubio E, Cotovad L, et al. Ultrarapid insulin use can reduce postprandial hyperglycemia and late hypoglycemia, even in delayed insulin injections. A connected insulin cap-based real-world study. Diabetes Technol Ther. 2023. DOI:10.1089/dia.2023.0321.

Manka P, Coombes JD, Sydor S, Swiderska Syn MK, Best J, Gauthier K, et al. Thyroid hormone receptor alpha modulates fibrogenesis in hepatic stellate cells. Liver Int. 2023. DOI:10.1111/liv.15759.

Urritia I, Martinez R, Calvo B, Saso Jimenez L, Gonzalez P, Fernandez Rubio E, et al. Autoimmune Diabetes From Chilhood to Adulthood: The Role of Pancreatic Autoantibodies and HLA-DRB1 Genotype (vol 108, pg e1341, 2023). J Clin Endocrinol Metab. 2023. DOI:10.1210/clinem/dgad609.

Ochoa E, Lee S, Lan Leung B, Dias RP, Ong KK, Radley JA, et al. ImprintSeq, a novel tool to interrogate DNA methylation at human imprinted regions and diagnose multilocus imprinting disturbance. Genet Med. 2022; 24(2): 463-474. DOI:10.1016/j.gim.2021.10.011.

Ruiz de Gauna M, Biancaniello F, Gonzalez Romero F, Rodrigues PM, Lapitz A, Gomez Santos B, et al. Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids. Hepatology. 2022; 76(6): 1617-1633. DOI:10.1002/hep.32344.

Jebari Benslaiman S, Uribe KB, Benito Vicente A, Galicia Garcia U, Larrea Sebal A, Santin I, et al. Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple-Cell 2D Atherosclerosis Model. Small. 2022; 18(13). DOI:10.1002/smll.202105915.

Sot J, Garcia Arribas AB, Abad B, Arranz S, Portune K, Andrade F, et al. Erythrocyte Membrane Nanomechanical Rigidity Is Decreased in Obese Patients. Int J Mol Sci. 2022; 23(3). DOI:10.3390/ijms23031920.

Vazquez Mosquera ME, Gonzalez Vioque E, Barbosa Gouveia S, Bellido Guerrero D, Tejera Perez C, Martinez Olmos MA, et al. Transcriptomic analysis of patients with clinical suspicion of maturity-onset diabetes of the young (MODY) with a negative genetic diagnosis. Orphanet J Rare Dis. 2022; 17(1). DOI:10.1186/s13023-022-02263-3.

de Urturi DS, Buque X, Porteiro B, Folgueira C, Mora A, Delgado TC, et al. Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis. Nat Commun. 2022; 13(1): 1096-1096. DOI:10.1038/s41467-022-28749-z.

Olaizola P, Lee Law PY, Fernandez Barrena MG, Alvarez L, Cadamuro M, Azkargorta M, et al. Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumors-stroma crosstalk in experimental models. J Hepatol. 2022; 77(1): 177-190. DOI:10.1016/j.jhep.2022.02.007.

Gomez Munoz L, Perna Barrull D, Caroz Armayones JM, Murillo M, Rodriguez Fernandez S, Valls A, et al. Candidate Biomarkers for the Prediction and Monitoring of Partial Remission in Pediatric Type 1 Diabetes. Front Immunol. 2022; 13. DOI:10.3389/fimmu.2022.825426.

Ochoa E, Lee S, Lan Leung B, Dias R, Ong KK, Radley JA, et al. New diagnostic tool for multi-locus imprinting disturbances. Eur J Hum Genet. 2022; 30(SUPPL 1): 549-550

Moral Martos A, Guerrero Fernandez J, Gomez Balaguer M, Rica Echevarria I, Campos Martorell A, Chueca Guindulain MJ, et al. Clinical practice guidelines for transsexual, transgender and gender diverse minors. An Pediatr (Engl Ed). 2022; 96(4): 3491-34911. DOI:10.1016/j.anpede.2022.02.002.

Castano L, Madariaga L, Grau G, Garcia Castano A. 25(OH)Vitamin D Deficiency and Calcifediol Treatment in Pediatrics. Nutrients. 2022; 14(9). DOI:10.3390/nu14091854.

Exposito Rodriguez A, Corta Gomez I, Dominguez Ayala M, Garcia Carrillo M, Gonzalez Garcia AI, Gutierrez Rodriguez MT, et al. Sentinel lymph node biopsy in papillary thyroid cancer: Accuracy and application in clinical practice. Cir Esp (Engl Ed). 2022; 100(7): 416-421. DOI:10.1016/j.cireng.2022.04.022.

Olaizola P, Rodrigues PM, Caballero Camino FJ, Izquierdo Sanchez L, Aspichueta P, Bujanda L, et al. Genetics, pathobiology and therapeutic opportunities of polycystic liver disease. Nat Rev Gastroenterol Hepatol. 2022; 19(9): 585-604. DOI:10.1038/s41575-022-00617-7.

Nowak C, Lind M, Sumnik Z, Pelikanova T, Chavez LN, Lundberg E, et al. Intralymphatic GAD-alum (Diamyd) improves glycaemic control in Type 1 diabetes with HLA DR3-DQ2. J Clin Endocrinol Metab. 2022; 107(9): 2644-2651. DOI:10.1210/clinem/dgac343.

Gonzalez Fenandez M, Antonio IED, Martin IMP, Martinez JS, Almaraz MCA. 5-Alpha-reductase type 2 deficiency. A new case in the Spanish population. Endocrinol Diabetes Nutr. 2022; 69(5): 384-386. DOI:10.1016/j.endien.2021.04.002.

Cruz R, Almeida SD, Heredia ML, Quintela I, Ceballos FC, Pita G, et al. Novel genes and sex differences in COVID-19 severity. Hum Mol Genet. 2022. DOI:10.1093/hmg/ddac132.

Labiano I, Agirre Lizaso A, Olaizola P, Echebarria A, Huici Izagirre M, Olaizola I, et al. TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation. J Hepatol. 2022; 77(4): 991-1004. DOI:10.1016/j.jhep.2022.05.044.

Garcia Perez J, Gonzalez Perez M, Castillo de la Osa M, Borobia AM, Castano L, Bertran MJ, et al. Immunogenic dynamics and SARS-CoV-2 variant neutralisation of the heterologous ChAdOx1-S/BNT162b2 vaccination: Secondary analysis of the randomised CombiVacS study. Eclinicalmedicine. 2022; 50: 101529-101529. DOI:10.1016/j.eclinm.2022.101529.

Ruiz de Gauna M, Biancaniello F, Gonzalez Romero F, Miguel Rodrigues P, Lapitz A, Gomez Santos B, et al. The uptake of extracellular lipids promotes cholangiocarcinoma progression. J Hepatol. 2022; 77: 648-648

Del Barrio Azaceta M, Iruzubieta P, Aller de la Fuente R, Maria Banales J, Santos Laso A, Calleja Panero JL, et al. The metabolic dysfunction-associated fatty liver disease definition, regardless of its clinical subclassification, identifies patients at high risk for liver disease progression. J Hepatol. 2022; 77: 158-159

Gomez Santos B, Fernamdez Puertas I, Nieva Zuluaga A, Ruiz de Gauna M, Apodaka Biguri M, Gonzalez Romero F, et al. The DNA damage response is involved in the metabolic dysregulation of MAFLD patients via inefficient fatty acid oxidation. J Hepatol. 2022; 77: 665-665

Olaizola P, Lee Law P, Fernandez Barrena MG, Alvarez L, Cadamuro M, Azkargorta M, et al. Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumour-stroma crosstalk in experimental models. J Hepatol. 2022; 77: 46-46

Apodaka Biguri M, Gonzalez Romero F, Mestre Congregado D, Aurrekoetxea I, Gomez Santos B, Delgado I, et al. miR34a-5p is a target of E2F2 transcription factor in MAFLD-related HCC. J Hepatol. 2022; 77: 651-652

Buque X, Porteiro B, Folgueira C, Mora A, Cardoso Delgado T, Prieto Fernandez E, et al. Methionine adenosyltransferase 1a antisense oligonucleotides induce the fibroblast growth factor 21-driven recovery from obesity and associated hepatoesteatosis. J Hepatol. 2022; 77: 689-690

Del Barrio Azaceta M, Iruzubieta P, Aller De La Fuente R, Maria Banales J, Santos Laso A, Calleja Panero JL, et al. Metabolic dysfunction-associated fatty liver disease increases cardiovascular risk regardless of classical risk factors. J Hepatol. 2022; 77: 157-157

Vallejo Casas JA, Sambo M, Lopez C, Duran Poveda M, Rodriguez Villanueva Garcia J, Santos RJ, et al. Initial clinical and treatment patterns of advanced differentiated thyroid cancer: ERUDIT study. Eur Thyroid J. 2022; 11(5). DOI:10.1530/ETJ-21-0111.

Diez JJ, Anda E, Alcazar V, Isidro ML, Familiar C, Paja M, et al. Differentiated thyroid carcinoma in the elderly: influence of age on disease-free and overall survival. Endocrine. 2022; 77(1): 121-133. DOI:10.1007/s12020-022-03059-y.

Valdes S, Doulatram Gamgaram V, Maldonado Araque C, Lago Sampedro A, Garcia Escobar E, Garcia Serrano S, et al. Ambient air pollution and thyroid function in Spanish adults. A nationwide population-based study (Di@bet.es study). Environ Health. 2022; 21(1). DOI:10.1186/s12940-022-00889-1.

Lago Sampedro A, Lhamyani S, Valdes S, Colomo N, Maldonado Araque C, Gonzalez Molero I, et al. Serum vascular endothelial growth factor b and metabolic syndrome incidence in the population based cohort Di@bet.es study. Int J Obes. 2022; 46(11): 2013-2020. DOI:10.1038/s41366-022-01212-1.

Garcia E, Alvarez Del Vayo C, Castano L. Familial male-limited precocious puberty (testotoxicosis): Usefulness of treatment with ketoconazole and triptorelin. Med Clin. 2022; 159(11): 79-80. DOI:10.1016/j.medcli.2022.08.007.

Kouri C, Sommer G, Martinez de LaPiscina I, Tack L, Cools M, Flueck CE. The international SF1 next project: Description of a cohort of 107 individuals with SF-1/NR5A1 variants. Sex Dev. 2022; 16(SUPPL 1): 23-24

Martinez de LaPiscina I, Kouri C, Sommer G, Tack L, Cools M, Flueck CE, et al. Spectrum of SF-1/NR5A1 gene variants in the large international SF1next cohort. Sex Dev. 2022; 16(SUPPL 1): 65-66

Garcia Castano A, Gomez Conde S, Madariaga L, Ariceta G. NEW FAMILY WITH KCNJ16 GENE TUBULOPATHY, CHARACTERIZED BY HYPOKALEMIA, IMPAIRED ACID-BASE HOMEOSTASIS AND SENSORINEURAL HEARING LOSS. Pediatr Nephrol. 2022; 37(11): 2874-2875

Mendizabal L, Arregi M, Deogracia JV, Levi AMR, Barabash A, De la Torre NG, et al. New Gestational Diabetes Mellitus Risk Algorithm. Diabetes. 2022; 71. DOI:10.2337/db22-156-LB.

Biagetti B, Iglesias P, Villar Taibo R, Moure M, Paja M, Araujo Castro M, et al. Factors associated with therapeutic response in acromegaly diagnosed in the elderly in Spain. Front Endocrinol. 2022; 13: 984877-984877. DOI:10.3389/fendo.2022.984877.

Hamidi M, Eriz A, Mitxelena J, Fernandez Ares L, Aurrekoetxea I, Aspichueta P, et al. Targeting E2F Sensitizes Prostate Cancer Cells to Drug-Induced Replication Stress by Promoting Unscheduled CDK1 Activity. Cancers (Basel). 2022; 14(19). DOI:10.3390/cancers14194952.

de LaPiscina IM, Kouri C, Sommer G, Tack L, Cools M, Fluck C, et al. SF1next study: spectrum of SF-1/NR5A1 gene variants in this large international cohort. Horm Res Paediatr. 2022; 95(SUPPL 2): 109-109

Grau G, Andrade F, Vela A, Lopez Oceja R, Rica I. Bisphenol A (BPA): A hidden enemy. Horm Res Paediatr. 2022; 95(SUPPL 2): 536-536

Kouri C, Sommer G, Martinez de LaPiscina I, Tack L, Cools M, Fluck CE, et al. Phenotypes in a large international cohort of individuals with SF-1/NR5A1 variants. Horm Res Paediatr. 2022; 95(SUPPL 2): 46-46

Marcelo I, Urrutia I, Calvo B, Martinez R, Saso L, Castano L, et al. Prevalence of autoimmunity in relatives of patients with type 1 diabetes: Time to the clinical onset of diabetes and associated risk factors. Horm Res Paediatr. 2022; 95(SUPPL 2): 177-178

Hirschler V, Gonzalez CD, Itxaso R, Ines U, Zalazar Rosa M, Anibal A, et al. Association between Hepcidin and Type 2 Diabetes markers In Indigenous Argentinean Children living at High Altitude. Clin Chim Acta. 2022; 537: 194-198. DOI:10.1016/j.cca.2022.08.021.

Nunez Munoz R, Ortega YC, Sarmiento M, Jorge RV, Fuentes AP, Subirats JG, et al. Stimulated thyroglobulin ( TG) prior to [131I] therapy (RAIT) in patients with differentiated thyroid cancer (DTC) as a predictive factor of recurrence. Eur J Nucl Med Mol Imaging. 2022; 49(SUPPL 1): 586-586

Martin Fernandez M, Arroyo V, Carnicero C, Siguenza R, Busta R, Mora N, et al. Role of Oxidative Stress and Lipid Peroxidation in the Pathophysiology of NAFLD. Antioxidants. 2022; 11(11). DOI:10.3390/antiox11112217.

Guerrero Fernandez J, Gonzalez Peramato P, Rodriguez Estevez A, Alcazar Villar MJ, Audi Parera L, Azcona San Julian MC, et al. Consensus guide on prophylactic gonadectomy in different sex development. Endocrinol Diabetes Nutr. 2022; 69(8): 629-645. DOI:10.1016/j.endien.2022.10.002.

Velasco I, Vila L, Goya M, Oleaga A, de la Calle M, Santamaria FJ. Executive summary of the SEEN (Sociedad Espanola de Endocrinologia y Nutricion[Spanish Society of Endocrinology and Nutrition])-SEGO (Sociedad Espanola deGinecologia y Obstetricia [Spanish Society of Gynaecology and Obstetrics]) consensusdocument on the management of thyroid dysfunction during pregnancy. Endocrinol Diabetes Nutr. 2022. DOI:10.1016/j.endien.2022.11.008.

Lanes Iglesias S, Megido Armada A, Castano Gonzalez LA, Menendez Torre EL, Riano Galan I. Experience in diagnosis and treatment of prolactinomas in pediatric patients and young adults. Endocrinol Diabetes Nutr. 2022; 69(10): 911-913. DOI:10.1016/j.endien.2022.11.028.

Gomez Peralta F, Abreu C, Fernandez Rubio E, Cotovad L, Pujante P, Gaztambide S, et al. Efficacy of a Connected Insulin Pen Cap in People With Noncontrolled Type 1 Diabetes: A Multicenter Randomized Clinical Trial. Diabetes Care. 2022; 46(1): 206-208. DOI:10.2337/dc22-0525.

Greeley SAW, Polak M, Njolstad PR, Barbetti F, Williams R, Castano L, et al. ISPAD Clinical Practice Consensus Guidelines 2022: The diagnosis and management of monogenic diabetes in children and adolescents. Pediatr Diabetes. 2022; 23(8): 1188-1211. DOI:10.1111/pedi.13426.

Nogueiras R, Aspichueta P. Expanding the roles of the renin-angiotensin system: Drug-induced liver injury. J Hepatol. 2023; 78(3): 457-459. DOI:10.1016/j.jhep.2022.12.016.

Jauregibeitia I, Portune K, Gaztambide S, Rica I, Tueros I, Velasco O et al. Molecular Differences Based on Erythrocyte Fatty Acid Profile to Personalize Dietary Strategies between Adults and Children with Obesity. Metabolites. 2021; 11(1). DOI:10.3390/metabo11010043.

Nucci AM, Virtanen SM, Cuthbertson D, Ludvigsson J, Einberg U, Huot C et al. Growth and development of islet autoimmunity and type 1 diabetes in children genetically at risk. Diabetologia. 2021; 64(4): 826-835. DOI:10.1007/s00125-020-05358-3.

Sebastian delaCruz M, Gonzalez Moro I, Olazagoitia Garmendia A, Castellanos Rubio A, Santin I. The Role of lncRNAs in Gene Expression Regulation through mRNA Stabilization. Non-coding RNA. 2021; 7(1). DOI:10.3390/ncrna7010003.

Infante A, Gener B, Vazquez M, Olivares N, Arrieta A, Grau G et al. Reiterative infusions of MSCs improve pediatric osteogenesis imperfecta eliciting a pro-osteogenic paracrine response: TERCELOI clinical trial. Clin Transl Med. 2021; 11(1): 265-265. DOI:10.1002/ctm2.265.

Garcia Castano A, Madariaga L, Gomez Conde S, Cordo CLR, Lopez Iglesias M, Garcia Fernandez Y et al. Five patients with disorders of calcium metabolism presented with GCM2 gene variants. Sci Rep. 2021; 11(1): 2968-2968. DOI:10.1038/s41598-021-82661-y.

Urrutia I, Martin Nieto A, Martinez R, Casanovas Marsal JO, Aguayo A, Del Olmo J et al. Incidence of diabetes mellitus and associated risk factors in the adult population of the Basque country, Spain. Sci Rep. 2021; 11(1): 3016-3016. DOI:10.1038/s41598-021-82548-y.

Simon J, Goikoetxea Usandizaga N, Serrano Macia M, Fernandez Ramos D, Saenz de Urturi D, Gruskos JJ et al. Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH. J Hepatol. 2021; 75(1): 34-45. DOI:10.1016/j.jhep.2021.01.043.

Gonzalez Moro I, Santin I. Long non-coding RNA-regulated pathways in pancreatic beta cells: Their role in diabetes. Int Rev Cell Mol Biol. 2021; 359: 325-355. DOI:10.1016/bs.ircmb.2021.02.007.

Gonzalez Romero F, Mestre D, Aurrekoetxea I, O'Rourke CJ, Andersen JB, Woodhoo A et al. E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment. Cancer Res. 2021; 81(11): 2874-2887. DOI:10.1158/0008-5472.CAN-20-2052.

Pinart M, Jeran S, Boeing H, Stelmach Mardas M, Standl M, Schulz H et al. Dietary Macronutrient Composition in Relation to Circulating HDL and Non-HDL Cholesterol: A Federated Individual-Level Analysis of Cross-Sectional Data from Adolescents and Adults in 8 European Studies. J Nutr. 2021; 151(8): 2317-2329. DOI:10.1093/jn/nxab077.

Zenarruzabeitia O, Astarloa Pando G, Terren I, Orrantia A, Perez Garay R, Seijas Betolaza I et al. T Cell Activation, Highly Armed Cytotoxic Cells and a Shift in Monocytes CD300 Receptors Expression Is Characteristic of Patients With Severe COVID-19. Front Immunol. 2021; 12. DOI:10.3389/fimmu.2021.655934.

Gomez Conde S, Garcia Castano A, Aguirre M, Herrero M, Gondra L, Garcia Perez N et al. Molecular aspects and long-term outcome of patients with primary distal renal tubular acidosis. Pediatr Nephrol. 2021; 36(10): 3133-3142. DOI:10.1007/s00467-021-05066-z.

Jauregibeitia I, Portune K, Rica I, Tueros I, Velasco O, Grau G et al. Potential of Erythrocyte Membrane Lipid Profile as a Novel Inflammatory Biomarker to Distinguish Metabolically Healthy Obesity in Children. J Pers Med. 2021; 11(5). DOI:10.3390/jpm11050337.

Ampuero J, Aller R, Gallego Duran R, Crespo J, Abad J, Gonzalez Rodriguez A et al. Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis: A longitudinal study of 1893 biopsy-proven nonalcoholic fatty liver disease subjects. Liver Int. 2021; 41(9): 2076-2086. DOI:10.1111/liv.14898.

Cabrera D, Rao I, Raasch F, Solis N, Pizarro M, Freire M et al. Mineralocorticoid receptor modulation by dietary sodium influences NAFLD development in mice. Ann Hepatol. 2021; 24: 100357-100357. DOI:10.1016/j.aohep.2021.100357.

Villalabeitia Ateca I, Perfecto Valero A, Serrano Hermosilla C, Marcaida Salazar A, Perez Fernandez S, Sarriugarte Lasarte A. Prognostic value of the nodal ratio in gastric cancer: Unicentric analysis pf 199 patients. Cir Esp (Engl Ed). 2021. DOI:10.1016/j.ciresp.2021.03.018.

Gonzalez Moro MB, Gonzalez Moro I, de la Pena M, Estavillo JM, Aparicio Tejo PM, Marino D et al. A Multi-Species Analysis Defines Anaplerotic Enzymes and Amides as Metabolic Markers for Ammonium Nutrition. Front Plant Sci. 2021; 11. DOI:10.3389/fpls.2020.632285.

Ludvigsson J, Sumnik Z, Pelikanova T, Nattero Chavez L, Lundberg E, Rica I et al. Intralymphatic Glutamic Acid Decarboxylase With Vitamin D Supplementation in Recent-Onset Type 1 Diabetes: A Double-Blind, Randomized, Placebo-Controlled Phase IIb Trial. Diabetes Care. 2021. DOI:10.2337/dc21-0318.

Morales C, Bellido V, Tejera C, Goni F, Palomares R, Sevillano C et al. DAPA-RWE: a retrospective multicenter study comparing dapagliflozin and sitagliptin in patients with Type 2 diabetes treated under routine clinical practice in Spain. J Comp Eff Res. 2021; 10(10): 815-821. DOI:10.2217/cer-2020-0264.

Santamaria Sandi J, Navarro Gonzalez E, Herrero Ruiz A, Bandres Nivela O, Ballesteros Pomar M, Escalada San Martin FJ et al. Portfolio of services in Endocrinology and Nutrition. 2020 update. Endocrinol Diabetes Nutricion. 2021. DOI:10.1016/j.endinu.2021.01.006.

Pacaud D, Nucci AM, Cuthbertson D, Becker DJ, Virtanen SM, Ludvigsson J et al. Association between family history, early growth and the risk of beta cell autoimmunity in children at risk for type 1 diabetes. Diabetologia. 2021; 64(1): 119-128. DOI:10.1007/s00125-020-05287-1.

Gonzalez Fenandez M, Antonio IED, Martin IMP, Martinez JS, Almaraz MCA. 5-Alpha-reductase type 2 deficiency. A new case in the Spanish population. Endocrinol Diabetes Nutricion. 2021. DOI:10.1016/j.endinu.2021.04.003.

Serrano Macia M, Simon J, Gonzalez Rellan MJ, Azkargorta M, Goikoetxea Usandizaga N, Lopitz Otsoa F et al. Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis. Mol Metab. 2021; 53: 101275-101275. DOI:10.1016/j.molmet.2021.101275.

Arif E, Wang C, Swiderska Syn MK, Solanki AK, Rahman B, Manka PP et al. Targeting myosin 1c inhibits murine hepatic fibrogenesis. Am J Physiol-Gastroint Liver Physiol. 2021; 320(6): 1044-1053. DOI:10.1152/ajpgi.00105.2021.

Borobia AM, Carcas AJ, Perez Olmeda M, Castano L, Bertran MJ, Garcia Perez J et al. Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial. Lancet. 2021; 398(10295): 121-130. DOI:10.1016/S0140-6736(21)01420-3.

Fernandez U, Fernandez Fondevila M, Gonzalez Rellan MJ, Da Silva Lima N, Buque X, Gonzalez A et al. Hepatic LPI/GPR55 systemregulates the development of non-alcoholic steatosis and steatohepatitis. J Hepatol. 2021; 75: 389-391

Simon J, Goikoetxea N, Serrano Macia M, Fernandez Ramos D, Saenz de Urturi D, Gruskos J et al. Hepatic magnesium accumulation upon cyclin M4 (CNNM4) silencing improves NASH. J Hepatol. 2021; 75: 612-612

Novoa E, da Silva Lima N, Fernandez Fondevila M, Buque X, Jesus Gonzalez M, Fernandez U et al. inhibition of atg3 ameliorates liver steatosis by increasing sirt1 in an autophagic-independent action. J Hepatol. 2021; 75: 591-591

Lee Law PY, Olaizola P, Caballero Camino FJ, Izquierdo Sanchez L, Rodrigues PM, Perugorria MJ et al. Inhibition of NAE-dependent protein hyper-NEDDylation in cystic cholangiocytes halts cystogenesis in experimental models of polycystic liver disease. United European Gastroenterol J. 2021; 9(7): 848-859. DOI:10.1002/ueg2.12126.

Serrano Macia M, Simon Espinosa J, Gonzalez Rellan MJ, Goikoetxea N, Azkargorta M, Lopitz Otsoa F et al. Neddylation inhibition reduces liver steatosis in MAFLD mice models by promoting hepatic fatty acid oxidation via DEPTOR-mTOR axis. J Hepatol. 2021; 75: 624-624

Gonzalez Romero F, Mestre Congregado D, Aurrekoetxea I, Rourke CO, Andersen J, Woodhoo A et al. Repression of fatty acid oxidation in steatohepatitic-HCC is mediated by E2F1 and E2F2 transcription factors. J Hepatol. 2021; 75: 497-498

Martinez de LaPiscina I, Portillo Najera N, Rica I, Gaztambide S, Webb S, Santos A et al. Clinical and genetic characteristics in patients under 30 years with sporadic pituitary adenomas. Eur J Endocrinol. 2021; 185(4): 485-496. DOI:10.1530/EJE-21-0075.

Gonzalez Moro I, Sebastian delaCruz M, Rojas Marquez H, Olazagoitia Garmendia A, Mentxaka J, Mendoza LM et al. A long non-coding RNA that harbors a SNP associated with insulin levels regulates TGM2 gene expression in pancreatic beta cells. Diabetologia. 2021; 64(SUPPL 1): 8-9

Garcia Escobar E, Valdes S, Soriguer F, Vendrell J, Urrutia Etxebarria IM, Maldonado Araque C et al. Fatty liver index as a predictor for type 2 diabetes in subjects with normoglycemia in a nationwide cohort study. Sci Rep. 2021; 11(1). DOI:10.1038/s41598-021-95546-x.

da Silva Lima N, Fondevila MF, Novoa E, Buque X, Mercado Gomez M, Gallet S et al. Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function. J Hepatol. 2021; 76(1): 11-24. DOI:10.1016/j.jhep.2021.09.008.

Zurita ALP, Appelman Dijkstra N, Biermasz N, Bryce J, Burman P, Castano L et al. The Pituitary Tumour Module: Developing a Condition Specific Module within the European Registries for Rare Endocrine Conditions (EuRRECa). Horm Res Paediatr. 2021; 94(SUPPL 1): 113-113

Martinez de LaPiscina I, Portillo N, Rica I, Gaztambide S, Castano L. Sporadic pituitary adenomas in young patients: clinical and molecular description. Horm Res Paediatr. 2021; 94(SUPPL 1): 108-109

Mejia de Beldjenna L, Garcia Castano A, Gomez Conde S, Castano L. Primary hyperparathyroidism due to a deletion of the CDC73 gene. Horm Res Paediatr. 2021; 94(SUPPL 1): 215-215

Doulatram Gamgaram V, Valdes S, Maldonado Araque C, Lago Sampedro A, Badia Guillen R, Garcia Escobar E et al. Association between long term exposure to particulate matter and incident hypertension in Spain. Sci Rep. 2021; 11(1). DOI:10.1038/s41598-021-99154-7.

Madariaga L, Gomez Conde S, Garcia Castano A, Aguirre M, Herrero M, Gondra L et al. LONG-TERM OUTCOME OF A SERIES OF PATIENTS WITH PRIMARY DISTAL RENAL TUBULAR ACIDOSIS. Pediatr Nephrol. 2021; 36(10): 3367-3367

Martinez de LaPiscina I, Fluck CE. Genetics of human sexual development and related disorders. CURR OPIN PEDIATR. 2021; 33(6): 556-563. DOI:10.1097/MOP.0000000000001066.

Chueca MJ, Grau G, Bertholt L, Artola E, Fernandez C, Sarasua A et al. TBG deficiency and Central Congenital Hypothyroidism (CCH): Our experience in neonatal screening with TSH and T4. Horm Res Paediatr. 2021; 94(SUPPL 1): 417-418

Rica I, Garcia M, Grau G, Vela A, Rodriguez A, Luisa Guadilla M. Is the recommended dual therapy for transsexual boys harmless?. Horm Res Paediatr. 2021; 94(SUPPL 1): 381-382

Grau G, Laura Bertholt M, Chueca M, Artola E, Concepcion Fernandez M, Sarasua A et al. Early reassessment in congenital hypothyroidism. Horm Res Paediatr. 2021; 94(SUPPL 1): 407-408

Vela A, Regina Gonzalez M, Diaz C, Elorza A, Grau G, Rodriguez A et al. Anthropometric and clinical situation in two groups of young adults born Small for Gestational Age (a group with catch-up and another without catch-up and treated with Growth Hormone). Horm Res Paediatr. 2021; 94(SUPPL 1): 278-279

Diez JJ, Anda E, Sastre J, Corral BP, alvarez Escola C, Manjon L et al. Late Recovery of Parathyroid Function after Total Thyroidectomy: A Case-Control Study (Sep, 10.1055/a-1646-8410, 2021). HORM METAB RES. 2021. DOI:10.1055/a-1646-8410.

Diez JJ, Anda E, Sastre J, Corral BP, alvarez Escola C, Manjon L et al. Late Recovery of Parathyroid Function after Total Thyroidectomy: A Case-Control Study. HORM METAB RES. 2021; 53(10): 654-661. DOI:10.1055/a-1608-1373.

Maritxalar AI, Goni MH, Dominguez LM, Sangroniz LG, Menica MA, Castano AG et al. OUTCOME OF A COHORT OF PATIENTS WITH DENT DISEASE. Pediatr Nephrol. 2021; 36(10): 3312-3312

Sangroniz LG, Dominguez LM, Castano AG, Goni MH, Menica MA, Jaca AV et al. LONG-TERM FOLLOW-UP OF PATIENTS WITH BARTTER SYNDROME TYPE III. Pediatr Nephrol. 2021; 36(10): 3302-3303

Kouri C, Sommer G, Ahmed F, Balsamo A, Baronio F, Bryce J et al. Broad range of phenotypes in an international cohort of 75 DSD individuals with SF-1/NR5A1 variants. Horm Res Paediatr. 2021; 94(SUPPL 1): 87-89

Estevez Vazquez O, Benede Ubieto R, Guo F, Gomez Santos B, Aspichueta P, Reissing J et al. Fat: Quality, or Quantity? What Matters Most for the Progression of Metabolic Associated Fatty Liver Disease (MAFLD). Biomedicines. 2021; 9(10). DOI:10.3390/biomedicines9101289.

Perez Valle A, Abad Garcia B, Fresnedo O, Barreda Gomez G, Aspichueta P, Asumendi A et al. A UHPLC-Mass Spectrometry View of Human Melanocytic Cells Uncovers Potential Lipid Biomarkers of Melanoma. Int J Mol Sci. 2021; 22(21). DOI:10.3390/ijms222112061.

Alonso SP, Valdes S, Maldonado Araque C, Lago A, Ocon P, Calle A et al. Thyroid hormone resistance index and mortality in euthyroid subjects: Di@bet.es study. Eur J Endocrinol. 2021; 186(1): 95-103. DOI:10.1530/EJE-21-0640.

Santamans AM, Montalvo Romeral V, Mora A, Lopez JA, Gonzalez Romero F, Jimenez Blasco D et al. p38gamma and p38delta regulate postnatal cardiac metabolism through glycogen synthase 1. PLoS Biol. 2021; 19(11). DOI:10.1371/journal.pbio.3001447.

Fernandez LS, Iturriaga LAR, Yandiola PPE, Ocana RM, Fernandez SP, Huget ET et al. BACTERAEMIC PNEUMOCOCCAL PNEUMONIA AND SARS-CoV-2 PNEUMONIA: DIFFERENCES AND SIMILARITIES. Int J Infect Dis. 2021; 115: 39-47. DOI:10.1016/j.ijid.2021.11.023.

Serrano Macia M, Espinosa JS, Gonzalez Rellan MJ, Azkargorta M, Goikoetxea Usandizaga N, Lopitz Otsoa F et al. NEDDYLATION INHIBITION REDUCES LIVER STEATOSIS IN MAFLD MICE MODELS BY PROMOTING HEPATIC FATTY ACID OXIDATION VIA DEPTOR-mTOR AXIS. Hepatology. 2021; 74: 1146-1147

Espinosa JS, Goikoetxea Usandizaga N, Serrano Macia M, Ramos DF, De Urturi DS, Gruskos JJ et al. MAGNESIUM ACCUMULATION UPON CYCLIN M4 SILENCING AMELIORATES NON-ALCOHOLIC STEATOHEPATITIS. Hepatology. 2021; 74: 1143-1144

Cardon EB, Arrospide A, Ugarte HA, Etxebarria IU, Gonzalez LG, Etxebarria I et al. Diet as a risk factor for hypovitaminosis D in the Spanish pediatric population. Rev Osteoporos Metab Min. 2021; 13(4): 122-129. DOI:10.4321/S1889-836X2021000300004.

Sonia G, Button EA, Zulueta M, Arana E, de la Hoz AB, Mendizabal L et al. Association of Serum 1,5-Anhydroglucitol with Severe COVID-19 in T2D patients. Diabetes. 2021; 70. DOI:10.2337/db21-146-LB.

Munoz RN, Ortega YC, Sarmiento M, Jorge RV, Herrero MN, Subirats JG et al. Postoperative basal serum thyroglobuline (TG) prior to radioiodine therapy as a predictive factor of recurrence in patients with differentiated thyroid cancer (DTC). Eur J Nucl Med Mol Imaging. 2021; 48(SUPPL 1): 436-436

Ecenarro PS, Marina N, Perez Fernandez S, Tabernero E, Iriberri M, Celli B. Paradoxical bronchoconstriction after administration of beta-2 agonist bronchodilators in COPD patients. Eur Resp J. 2021; 58. DOI:10.1183/13993003.congress-2021.PA3437.

Iturriaga L, Fernandez LS, Quero BG, Bonilla AG, Fernandez SP, Carasusan AR et al. Lymphopenic community acquired pneumococcal pneumonia: Clinical characteristics and outcome. Eur Resp J. 2021; 58. DOI:10.1183/13993003.congress-2021.PA1749.

Fernandez LS, Iturriaga L, Yandiola P, Ocana RM, Fernandez SP, Huget ET et al. Bacteraemic pneumococcal pneumonia and SARS-CoV-2 pneumonia: differences and similarities. Eur Resp J. 2021; 58. DOI:10.1183/13993003.congress-2021.PA1750.

Pando GA, Zenarruzabeitia O, Terren I, Orrantia A, Garay RP, Betolaza IS et al. T cell activation, highly armed cytotoxic cells and a shift in monocytes CD300 receptors expression in severe COVID-19. Eur J Immunol. 2021; 51: 267-267

Oyanguren J, Diaz Molina B, Lekuona I, Gonzalez Costello J, Lopez Fernandez S, Garcia Pinilla JM et al. Gender differences in drug titration among heart failure patients with reduced ejection fraction in the ETIFIC trial. Rev Esp Cardiol (Engl Ed). 2021. DOI:10.1016/j.rec.2021.11.002.

Orrantia A, Terren I, Pando GA, Gonzalez C, Uranga A, Mazon JJM et al. High frequency of mature CD57+NKG2A-NK cells associate with poor disease progression after autologous hematopoietic stem cell transplantation in multiple myeloma patients. Eur J Immunol. 2021; 51: 271-271

Valdivia A, Cortes L, Beitia M, Totorikaguena L, Agirregoitia N, Corcostegui B, et al. Role of Angiotensin-(1-7) via Mas receptor in human sperm motility and acrosome reaction. Reproduction. 2020; 159(3): 241-249. DOI:10.1530/REP-19-0274.

Fadini GP, Tentolouris N, Caballero Mateos I, Bellido Castañeda V, Morales Portillo C. A Multinational Real-World Study on the Clinical Characteristics of Patients with Type 2 Diabetes Initiating Dapagliflozin in Southern Europe. Diabetes Ther. 2020; 11(2): 423-436. DOI:10.1007/s13300-019-00744-6.

Pinés Corrales PJ, Bellido Castañeda V, Ampudia Blasco FJ. Update on postprandial hyperglycaemia: the pathophysiology, prevalence, consequences and implications of treating diabetes. Rev Clin Esp. 2020; 220(1): 57-68. DOI:10.1016/j.rce.2018.06.015.

García Castaño A, Madariaga L, Pérez de Nanclares G, Vela A, Rica I, Gaztambide S, et al. Forty-one individuals with mutations in the AVP-NPII gene associated with familial neurohypophyseal diabetes insipidus. J Clin Endocrinol Metab. 2020; 105(4). DOI:10.1210/clinem/dgaa069.

Fuertes Mendizabal T, Irica Bastias E, Gonzalez Murua C, Begona Gonzalez Moro MA. Nitrogen Assimilation in the Highly Salt- and Boron-Tolerant Ecotype Zea mays L. Amylacea. Plants-Basel. 2020; 9(3). DOI:10.3390/plants9030322.

Gonzalez Moro I, Olazagoitia Garmendia A, Colli ML, Cobo Vuilleumier N, Postler TS, Marselli L, et al. The T1D-associated lncRNA Lnc13 modulates human pancreatic beta cell inflammation by allele-specific stabilization of STAT1 mRNA. Proc Natl Acad Sci U S A. 2020; 117(16): 9022-9031. DOI:10.1073/pnas.1914353117.

Fondevila MF, Fernandez U, Gonzalez Rellan MJ, Da Silva Lima N, Buque X, Gonzalez Rodriguez A, et al. The L-a-lysophosphatidylinositol/GPR55 system induces the development of non-alcoholic steatosis and steatohepatitis. Hepatology. 2020; 73(2): 606-624. DOI:10.1002/hep.31290.

Simon J, Nuñez García M, Fernández Tussy P, Barbier Torres L, Fernández Ramos D, Gómez Santos B, et al. Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly. Cell Metab. 2020; 31(3). DOI:10.1016/j.cmet.2020.01.013.

Rojo Martínez G, Valdés S, Soriguer F, Vendrell J, Urrutia I, Pérez V, et al. Incidence of diabetes mellitus in Spain as results of the nation-wide cohort di@bet.es study. Sci Rep. 2020; 10(1): 2765-2765. DOI:10.1038/s41598-020-59643-7.

García Castaño A, Madariaga L, Pérez de Nanclares G, Vela A, Rica I, Gaztambide S, et al. Response to Letter to the Editor: "Forty-One Individuals With Mutations in the AVP-NPII Gene Associated With Familial Neurohypophyseal Diabetes Insipidus". J Clin Endocrinol Metab. 2020; 105(7): 2687-2688. DOI:10.1210/clinem/dgaa255.

Sentchordi Montane L, Benito Sanz S, Aza Carmona M, Pereda A, Parrón M, de la Torre C, et al. Clinical and Molecular Description of 16 Families With Heterozygous IHH Variants. J Clin Endocrinol Metab. 2020; 105(8): 2654-2666. DOI:10.1210/clinem/dgaa218.

Moreno P, de la Quintana Basarrate A, Musholt TJ, Paunovic I, Puccini M, Vidal Ó, et al. Laparoscopy versus open adrenalectomy in patients with solid tumor metastases: results of a multicenter European study. Gland Surg. 2020; 9(Suppl 2). DOI:10.21037/gs.2019.10.15.

Bellido V, Perez A. Consequences of COVID-19 on people with diabetes. Endocrinol Diabetes Nutricion. 2020. DOI:10.1016/j.endinu.2020.04.001.

Ampuero J, Aller R, Gallego Duran R, Crespo J, Calleja JL, Garcia Monzon C, et al. Erratum to: "Significant fibrosis predicts new-onset diabetes mellitus and arterial hypertension in patients with NASH (J Hepatol 2020; 73: 17-25). J Hepatol. 2020; 73(3): 740-741. DOI:10.1016/j.jhep.2020.06.018.

Gomez Santos B, Saenz de Urturi D, Nunez Garcia M, Gonzalez Romero F, Buque X, Aurrekoetxea I, et al. Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease. Aging Cell. 2020; 19(8): 13183-13183. DOI:10.1111/acel.13183.

Barbier Torres L, Fortner KA, Iruzubieta P, Delgado TC, Giddings E, Chen Y, et al. Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation. Nat Commun. 2020; 11(1): 3360-3360. DOI:10.1038/s41467-020-16991-2.

Oyaguez I, Merino Torres JF, Brito M, Bellido V, Cardona Hernandez R, Gomez Peralta F, et al. Cost analysis of the flash monitoring system (FreeStyle Libre 2) in adults with type 1 diabetes mellitus. BMJ Open Diab Res Care. 2020; 8(1). DOI:10.1136/bmjdrc-2020-001330.

Fernandez E, Cortazar A, Bellido V. Impact of covid-19 lockdown on glycemic control in patients with type 1 diabetes. Diabetes Res Clin Pract. 2020; 166: 108348-108348. DOI:10.1016/j.diabres.2020.108348.

Martinez de LaPiscina I, Hernandez Ramirez LC, Portillo N, Gomez Gila AL, Urrutia I, Martinez Salazar R, et al. Rare Germline DICER1 Variants in Pediatric Patients With Cushing's Disease: What Is Their Role?. Front Endocrinol (Lausanne). 2020; 11: 433-433. DOI:10.3389/fendo.2020.00433.

Maldonado Araque C, Valdes S, Badia Guillen R, Lago Sampedro A, Colomo N, Garcia Fuentes E, et al. Iodine Deficiency and Mortality in Spanish Adults. Di@bet.es study. Thyroid. 2020; 31(1): 106-114. DOI:10.1089/thy.2020.0131.

Rubio PA, Curieses PB, Matos PP, Fernandez BH, Echevarria IR, Valles MM, et al. ARE THERE DIFFERENCES IN HEALTH-RELATED QUALITY OF LIFE IN CHILDREN AND TEENAGERS WITH TYPE 1 DIABETES BETWEEN INSULIN PUMP THERAPY AND MULTIPLE DOSE INJECTION THERAPY?. Diabetes Technol Ther. 2020; 22: 220-221

Rubio PA, Curieses PB, Valles MM, Matos PP, Fernandez BH, Estevez AR, et al. DIFFERENCES IN GLUCOSE MONITORING DATA AND HEALTH-RELATED QUALITY OF LIFE IN CHILDREN AND TEENAGERS WITH TYPE 1 DIABETES ACCORDING TO GLYCEMIC CONTROL. Diabetes Technol Ther. 2020; 22: 167-167

Rica Echevarria I, Garcia Del Monte J, Delgado Rubio A, Arcangeli F, Lotti T. Severe Hypertrichosis In Infants Due To Transdermic Exposure To 5% And 7% Topical Minoxidil. Dermatol Ther. 2020; 33(6): 14230-14230. DOI:10.1111/dth.14230.

Abulizi A, Vatner DF, Ye Z, Wang Y, Camporez J, Zhang D, et al. Membrane bound diacylglycerols explain the dissociation of hepatic insulin resistance from steatosis in MTTP-/- mice. J Lipid Res. 2020; 61(12): 1565-1576. DOI:10.1194/jlr.RA119000586.

Esparza Baquer A, Labiano I, Sharif O, Agirre Lizaso A, Oakley F, Rodrigues PM, et al. TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms. Gut. 2020; 70(7): 1345-1361. DOI:10.1136/gutjnl-2019-319227.

Bellido V, Martinez Arranz I, Goicolea I, Amor AJ, Pi J, Perez A, et al. Clinical Utility of a Noninvasive Metabolic Approach in Assessing the Prevalence of Nonalcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) in Type 2 Diabetes. Diabetes. 2020; 69. DOI:10.2337/db20-1477-P.

Bao A, Bellido V, Tejera C, Bellido D. Prevalence of Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes in a Spanish Population. Diabetes. 2020; 69. DOI:10.2337/db20-1524-P.

Lee Law PY, Olaizola P, Caballero Camino FJ, Izquierdo Sanchez L, Rodrigues PM, Santos Laso A, et al. Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models. J Hepatol. 2020; 74(2): 394-406. DOI:10.1016/j.jhep.2020.09.010.

Garcia Castano A, Madariaga L, Anton Gamero M, Mejia N, Ponce J, Gomez Conde S, et al. Novel variant in the CNNM2 gene associated with dominant hypomagnesemia. PLoS One. 2020; 15(9): 239965-239965. DOI:10.1371/journal.pone.0239965.

Cuesta M, Fuentes M, Rubio M, Bordiu E, Barabash A, Garcia de la Torre N, et al. Incidence and regression of metabolic syndrome in a representative sample of the Spanish population: results of the cohort di@bet.es study. BMJ Open Diab Res Care. 2020; 8(1). DOI:10.1136/bmjdrc-2020-001715.

Iglesias P, Nocete I, Moure Rodriguez MD, Venegas Moreno E, Ares J, Biagetti B, et al. CRANIOPHARYNGIOMA IN THE ELDERLY: A MULTICENTER AND NATION-WIDE STUDY IN SPAIN. Neuroendocrinology. 2020; 111(10): 925-936. DOI:10.1159/000512161.

Sebastian delaCruz M, Olazagoitia Garmendia A, Gonzalez Moro I, Santin I, Garcia Etxebarria K, Castellanos Rubio A. Implication of m6A mRNA Methylation in Susceptibility to Inflammatory Bowel Disease. Epigenomes. 2020; 4(3). DOI:10.3390/epigenomes4030016.

Martinez de LaPiscina I, Mahmoud RA, Sauter K, Esteva I, Alonso M, Costa I, et al. Variants of STAR, AMH and ZFPM2/FOG2 May Contribute towards the Broad Phenotype Observed in 46,XY DSD Patients with Heterozygous Variants of NR5A1. Int J Mol Sci. 2020; 21(22). DOI:10.3390/ijms21228554.

Jauregibeitia I, Portune K, Rica I, Tueros I, Velasco O, Grau G, et al. Fatty Acid Profile of Mature Red Blood Cell Membranes and Dietary Intake as a New Approach to Characterize Children with Overweight and Obesity. Nutrients. 2020; 12(11). DOI:10.3390/nu12113446.

Bellido V, Perez A. Inpatient Hyperglycemia Management and COVID-19. Diabetes Ther. 2020; 12(1): 121-132. DOI:10.1007/s13300-020-00966-z.

Colyn L, Barcena Varela M, Alvarez Sola G, Latasa MU, Uriarte I, Santamaria E, et al. Dual targeting of G9a and DNMT1 for the treatment of experimental cholangiocarcinoma. Hepatology. 2020; 73(6): 2380-2396. DOI:10.1002/hep.31642.

Benito Vicente A, Uribe KB, Rotllan N, Ramirez CM, Jebari Benslaiman S, Goedeke L, et al. miR-27b Modulates Insulin Signaling in Hepatocytes by Regulating Insulin Receptor Expression. Int J Mol Sci. 2020; 21(22). DOI:10.3390/ijms21228675.

Alloza I, Salegi A, Mena J, Navarro RT, Martin C, Aspichueta P, et al. BIRC6 Is Associated with Vulnerability of Carotid Atherosclerotic Plaque. Int J Mol Sci. 2020; 21(24). DOI:10.3390/ijms21249387.

Gomez Conde S, Garcia Castano A, Aguirre M, Herrero M, Gondra L, Castano L, et al. Hereditary distal renal tubular acidosis: Genotypic correlation, evolution to long term, and new therapeutic perspectives. Nefrologia. 2020; 41(4): 383-390. DOI:10.1016/j.nefro.2020.08.015.

Agirre L, de la Quintana A, Martinez G, Arana A, Servide MJ, Larrea J. Surgical results and the location of pathological glands in the treatment of primary sporadic hyperparathyroidism with negative preoperative 99mTc-sestamibi scintigraphy. Cir Espan. 2020. DOI:10.1016/j.ciresp.2020.11.011.

Garcia A, Madariaga L, Perez de Nanclares G, Vela A, Rica I, Gaztambide S, et al. Novel variants in the AVP-NPII gene associated with neurohypophyseal diabetes insipidus. Eur J Hum Genet. 2020; 28(SUPPL 1): 815-815

Ochoa E, Lee S, Lan Leung B, Gerontogianni L, Perez de Nanclares G, Martinez R, et al. ImprintSeq: A new sequencing panel to detect methylation alterations in human imprinted regions. Eur J Hum Genet. 2020; 28(SUPPL 1): 747-748

Gonzalez Moro I, Olazagoitia Garmendia A, Colli ML, Cobo Vuilleumier N, Postler TS, Marselli L, et al. The T1D-associated lncRNA Lnc13 modulates human pancreatic ss-cell inflammation by allele-specific stabilization of STAT1 mRNA. Eur J Hum Genet. 2020; 28(SUPPL 1): 998-998

Beltran D, Vega L. Bilinear identities involving the k-plane transform and Fourier extension operators. Proc R Soc Edinb Sect A-Math. 2020; 150(6): 3349-3377. DOI:10.1017/prm.2019.74.

Sarda S, Merrill D, Shin H, McGeachy A, Drews B, Lee W, et al. Highly Scalable and Automated Approach to Gut Microbiome Profiling and Quantification Using a New Ion Torrent Next-Generation Sequencing Assay. J Mol Diagn. 2020; 22(11): 49-49

Miettinen ME, Niinisto S, Erlund I, Cuthbertson D, Nucci AM, Honkanen J, et al. Serum 25-hydroxyvitamin D concentration in childhood and risk of islet autoimmunity and type 1 diabetes: the TRIGR nested case-control ancillary study. Diabetologia. 2020; 63(4): 780-787. DOI:10.1007/s00125-019-05077-4.

Dos Santos RS, Marroqui L, Velayos T, Olazagoitia Garmendia A, Jauregi Miguel A, Castellanos Rubio A, et al. DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway. Diabetologia. 2019; 62(3): 459-472. DOI:10.1007/s00125-018-4782-0.

Gaztambide S, Ramirez J, Gomez M, Montalban C, Ruiz R, Socias C, et al. Novel mutations associated with inherited human calcium-sensing receptor disorders: A clinical genetic study. Eur J Endocrinol. 2019; 180(1): 59-70. DOI:10.1530/EJE-18-0129.

Vela A, Perez Nanclares G, Rios I, Rica I, Portillo N, Castano L, et al. Thyroid hormone resistance from newborns to adults: a Spanish experience. J Endocrinol Invest. 2019; 42(8): 941-949. DOI:10.1007/s40618-019-1007-4.

Ibanez Perez J, Santos Zorrozua B, Lopez E, Irazusta J, Prieto B, Aparicio V, et al. Impact of physical activity on semen quality among men from infertile couples. Eur J Obstet Gynecol Reprod Biol. 2019; 237: 170-174. DOI:10.1016/j.ejogrb.2019.04.024.

Fernandez Ramos D, Mosca L, Goikoetxea N, Serrano Macia M, Cardoso Delgado T, Lopitz Otsoa F, et al. Metabolic implications of methionine adenosyltransferase 1A depletion during fasting. J Hepatol. 2019; 70(1): 550-550. DOI:10.1016/S0618-8278(19)31092-8.

Gonzalez Romero F, Mestre D, Aurrekoetxea I, Saenz de Urturi D, Gomez Santos B, Nunez Garcia M, et al. E2F2 mediated repression of fatty acid B-oxidation is mitigated through CREB1 in progressive non-alcoholic fatty liver disease. J Hepatol. 2019; 70(1): 9-9. DOI:10.1016/S0618-8278(19)30014-3.

Fernandez Rodriguez CM, Aller R, Luisa Gutierrez Garcia MA, Ampuero J, Gomez Camarero J, Martin Mateos RM, et al. Higher levels of serum uric acid influences hepatic damage in patients with non-alcoholic fatty liver disease (NAFLD). Rev Esp Enferm Dig. 2019; 111(4): 264-269. DOI:10.17235/reed.2019.5965/2018.

Goikoetxea N, Fernandez Ramos D, Serrano Macia M, Eugenia Cornide M, Jimenez Castro M, Alfano B, et al. MCJ: A therapeutic target in hepatic ischemia and reperfusion injury. J Hepatol. 2019; 70(1): 23-24. DOI:10.1016/S0618-8278(19)30040-4.

Fernandez Ramos D, Fernandez Tussy P, Lopitz Otsoa F, Simon J, Barbier Torres L, Gomez Santos B, et al. Mitochondrial GNMT-complex II is recovered by miR-873-5p targeting in NAFLD. J Hepatol. 2019; 70(1): 524-525. DOI:10.1016/S0618-8278(19)31038-2.

Cunarro J, Buque X, Casado S, Lugilde J, Vidal A, Mora A, et al. p107 Deficiency Increases Energy Expenditure by Inducing Brown-Fat Thermogenesis and Browning of White Adipose Tissue. Mol Nutr Food Res. 2019; 63(2). DOI:10.1002/mnfr.201801096.

Simon J, Fernandez Ramos D, Gutierrez de Juan V, Serrano Macia M, Goikoetxea N, Saenz de Urturi D, et al. Targeting NEDDylation protects liver from acute drug-induced damage. J Hepatol. 2019; 70(1): 429-429. DOI:10.1016/S0618-8278(19)30841-2.

Flueck CE, Audi L, Fernandez Cancio M, Sauter K, Martinez de LaPiscina I, Castano L, et al. Broad Phenotypes of Disorders/Differences of Sex Development in MAMLD1 Patients Through Oligogenic Disease. Front Genet. 2019; 10: 746-746. DOI:10.3389/fgene.2019.00746.

Valdes S, Doulatram Gamgaram V, Lago A, Garcia Torres F, Badia Guillen R, Olveira G, et al. Ambient temperature and prevalence of diabetes and insulin resistance in the Spanish population: Di@bet.es study. Eur J Endocrinol. 2019; 180(5): 275-282. DOI:10.1530/EJE-18-0818.

Castellanos Rubio A, Santin I, Olazagoitia Garmendia A, Romero Garmendia I, Jauregi Miguel A, Legarda M, et al. A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation. Sci Rep. 2019; 9. DOI:10.1038/s41598-019-40018-6.

Serrano Macia M, Azkargorta M, Simon J, Lopitz Otsoa F, Cardoso Delgado T, Fernandez Ramos D, et al. NEDDylation inhibition as a new potential therapy of nonalcoholic fatty liver disease. J Hepatol. 2019; 70(1): 546-546. DOI:10.1016/S0618-8278(19)31082-5.

Iruzubieta P, Barbier Torres L, Goikoetxea N, Cardoso Delgado T, Fernandez Ramos D, Varela Rey M, et al. Role of methylation-controlled J-protein, endogenous repressor of the mitochondrial respiratory chain, in cholestatic liver disease. J Hepatol. 2019; 70(1): 12-12. DOI:10.1016/S0618-8278(19)30021-0.

Lago Sampedro A, Garcia Escobar E, Rubio Martin E, Pascual Aguirre N, Valdes S, Soriguer F, et al. Dairy Product Consumption and Metabolic Diseases in the Di@bet.es Study. Nutrients. 2019; 11(2). DOI:10.3390/nu11020262.

Urrutia I, Martinez R, Rica I, Martinez de LaPiscina I, Garcia Castano A, Aguayo A, et al. Negative autoimmunity in a Spanish pediatric cohort suspected of type 1 diabetes, could it be monogenic diabetes?. PLoS One. 2019; 14(7). DOI:10.1371/journal.pone.0220634.

Lampasona V, Pittman DL, Williams AJ, Achenbach P, Schlosser M, Akolkar B, et al. Islet Autoantibody Standardization Program 2018 Workshop: Interlaboratory Comparison of Glutamic Acid Decarboxylase Autoantibody Assay Performance. Clin Chem. 2019; 65(9): 1141-1152. DOI:10.1373/clinchem.2019.304196.

Blarduni E, Arrospide A, Galar M, Castano L, Mar J. Factors associated with the prevalence of hypovitaminosis D in pregnant women and their newborns. An Pediatr. 2019; 91(2): 96-104. DOI:10.1016/j.anpede.2018.11.014.

Fernandez Tussy P, Fernandez Ramos D, Lopitz Otsoa F, Simon J, Barbier Torres L, Gomez Santos B, et al. miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease. Mol Metab. 2019; 29: 40-54. DOI:10.1016/j.molmet.2019.08.008.

Romero Garmendia I, Fernandez Jimenez N, Garcia Etxebarria K, Jauregi Miguel A, Olazagoitia Garmendia A, Santin I, et al. Where SNPs, coexpression and TADs intersect: new insights in the regulation of coexpression in celiac disease. Eur J Hum Genet. 2019; 27(1): 606-607

Rica I, Grau G, Vela A, Rodriguez A, Luisa Guadilla M. Paediatric Health Assistance to Transsexual Minor in the Multidisciplinary Care Unit of the Basque Country (Spain). Horm Res Paediatr. 2019; 91(1): 479-480

Grau G, Concepcion Fernandez M, Artola E, Sarasua A, Lizarralde E, Pintos C, et al. Diagnosis of central congenital hypothyroidism and multiple pituitary deficiencies through a neonatal screening program. Horm Res Paediatr. 2019; 91(1): 490-491

Reyes Garcia R, Moreno Perez O, Tejera Perez C, Fernandez Garcia D, Bellido Castaneda V, de la Torre Casares ML, et al. Document on a comprehensive approach to type 2 diabetes mellitus. Endocrinol Diabetes Nutr (Engl Ed). 2019; 66(7): 443-458. DOI:10.1016/j.endinu.2018.10.010.

Porteiro B, Fondevila MF, Buque X, Gonzalez Rellan MJ, Fernandez U, Mora A, et al. Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis. Mol Metab. 2018; 8: 132-143. DOI:10.1016/j.molmet.2017.12.005.

Santin I, Jauregi Miguel A, Velayos T, Castellanos Rubio A, Garcia Etxebarria K, Romero Garmendia I, et al. Celiac Diasease-associated lncRNA Named HCG14 Regulates NOD1 Expression in Intestinal Cells. J Pediatr Gastroenterol Nutr. 2018; 67(2): 225-231. DOI:10.1097/MPG.0000000000001970.

Lertxundi U, Hernandez R, San Miguel S, Corcostegui B, Prieto M, Gonzalez U, et al. The burden of constipation in psychiatric hospitals. Int J Psychiat Clin. 2018; 22(2): 143-150. DOI:10.1080/13651501.2017.1384023.

Romero Garmendia I, Garcia Etxebarria K, Hernandez Vargas H, Santin I, Jauregi Miguel A, Plaza Izurieta L, et al. Transcription Factor Binding Site Enrichment Analysis in Co-Expression Modules in Celiac Disease. Genes. 2018; 9(5). DOI:10.3390/genes9050245.

Bellido V, Larrañaga I, Vazquez F, Velasco V, Gaztambide S. Bone metastasis located on foot as a clinical presentation of an adrenocortical carcinoma. Endocrinol Diabetes Nutr (Engl Ed). 2018; 65(7): 418-419. DOI:10.1016/j.endinu.2018.03.007.

Blarduni E, Arrospide A, Galar M, Castaño L, Mar J, Grupo G. [Factors associated with the prevalence of hypovitaminosis D in pregnant women and their newborns]. Anales De Pediatria (barcelona, Spain : 2003). 2018. DOI:10.1016/j.anpedi.2018.11.012.

Hirschler V, Molinari C, Gonzalez C, Maccallini G, Castano LA. Prevalence of hypertension in argentinean indigenous children living at high altitudes versus US children. Clin Exp Hypertens. 2018; 40(8): 752-757. DOI:10.1080/10641963.2018.1431258.

Gonzalez T, Larretxi I, Vitoria JC, Castano L, Simon E, Churruca I, et al. Celiac Male's Gluten- Free Diet Profile: Comparison to that of the Control Population and Celiac Women. Nutrients. 2018; 10(11). DOI:10.3390/nu10111713.

Olazagoitia Garrnendia A, Santin I, Castellanos Rubio A. Functional implication of celiac disease associated lncRNAs in disease pathogenesis. Comput Biol Med. 2018; 102: 369-375. DOI:10.1016/j.compbiomed.2018.08.013.

Nunez Garcia M, Gomez Santos B, de Urturi DS, Mestre D, Gonzalez Romero F, Buque X, et al. Atorvastatin provides a new lipidome improving early regeneration after partial hepatectomy in osteopontin deficient mice. Sci Rep. 2018; 8. DOI:10.1038/s41598-018-32919-9.

Hattersley AT, Greeley S, Polak M, Rubio Cabezas O, Njolstad PR, Mlynarski W, et al. ISPAD Clinical Practice Consensus Guidelines 2018: The diagnosis and management of monogenic diabetes in children and adolescents. Pediatr Diabetes. 2018; 19(27): 47-63. DOI:10.1111/pedi.12772.

Vela A, De Lapiscina IM, De Nanclares GP, Amaia R, Rica I, Castano L, et al. Clinical and Molecular Characterization of One NR5A1 Gene Mutation Found in a Patient with 46, XY DSD. Horm Res Paediatr. 2018; 90(1): 592-593

Vela A, De Lapiscina IM, De Nanclares GP, Amaia R, Rica I, Castano L, et al. Clinical and Molecular Characterization of One NR5A1 Gene Mutation Found in a Patient with 46, XY DSD. Horm Res Paediatr. 2018; 90(1): 592-593

Ruzafa N, Pereiro X, Aspichueta P, Araiz J, Vecino E. The Retina of Osteopontin deficient Mice in Aging. Mol Neurobiol. 2018; 55(1): 213-221. DOI:10.1007/s12035-017-0734-9.

Aspichueta P. Lipid-rich environment: a key role promoting carcinogenesis in obesity-related non-alcoholic fatty liver disease. Gut. 2018; 67(8): 1376-1377. DOI:10.1136/gutjnl-2018-316047.

Romero Garmendia I, Jauregi Miguel A, Santin I, Bilbao JR, Castellanos Rubio A. Subcellular Fractionation from Fresh and Frozen Gastrointestinal Specimens. J Vis Exp. 2018. DOI:10.3791/57740.

Mogas E, Campos Martorell A, Clemente M, Castano L, Moreno Galdo A, Yeste D, et al. Successful use of cinacalcet to treat parathyroid-related hypercalcemia in two pediatric patients. Endocrinol Diabetes Metab Case Rep. 2018. DOI:10.1530/EDM-18-0009.

Maldonado Araque C, Valdes S, Lago Sampedro A, Lino Munoz JA, Garcia Fuentes E, Perez Valero V, et al. Iron deficiency is associated with Hypothyroxinemia and Hypotriiodothyroninemia in the Spanish general adult population: Di@bet.es study. Sci Rep. 2018; 8. DOI:10.1038/s41598-018-24352-9.

Ben Khelifa S, Martinez R, Dandana A, Khochtali I, Ferchichi S, Castano L. Maturity Onset Diabetes of the Young (MODY) in Tunisia: Low frequencies of GCK and HNF1A mutations. Gene. 2018; 651: 44-48. DOI:10.1016/j.gene.2018.01.081.

de LaPiscina IM, de Mingo C, Riedl S, Rodriguez A, Pandey AV, Fernandez Cancio M, et al. GATA4 Variants in Individuals With a 46,XY Disorder of Sex Development (DSD) May or May Not Be Associated With Cardiac Defects Depending on Second Hits in Other DSD Genes. Front Endocrinol (Lausanne). 2018; 9. DOI:10.3389/fendo.2018.00142.

Pinart M, Nimptsch K, Bouwman J, Dragsted LO, Yang C, De Cock N, et al. Joint Data Analysis in Nutritional Epidemiology: Identification of Observational Studies and Minimal Requirements. J Nutr. 2018; 148(2): 285-297. DOI:10.1093/jn/nxx037.

Martin I, Najera NP, Echevarria IR, Saenz SG, Gonzalez LC. Clinical and Molecular Characterization of Pediatric and Young Patients with Pituitary Adenomas. Horm Res Paediatr. 2018; 90(2): 11-12

Martin I, Najera NP, Echevarria IR, Saenz SG, Gonzalez LC. Clinical and Molecular Characterization of Pediatric and Young Patients with Pituitary Adenomas. Horm Res Paediatr. 2018; 90(2): 11-12

Castano AG, Madariaga L, Gaztambide S, Castano L. Clinical and Molecular Study of Patients with Hypercalcemia or Hypocalcemia and Alterations in the Calcium Sensor Receiver. Horm Res Paediatr. 2018; 90(2): 19-19

Martinez Salazar R, Aguayo Calcena A, Urrutia I, Vela A, Fernandez C, Castano L. Monogenic Diabetes and Congenital Hyperinsulinism Due to Dominant Mutations at the ATP-Dependent Potassium Channel SUR1 Subunit (ABCC8 Gene). Horm Res Paediatr. 2018; 90(2): 38-38

Martinez Salazar R, Aguayo Calcena A, Urrutia I, Vela A, Fernandez C, Castano L. Monogenic Diabetes and Congenital Hyperinsulinism Due to Dominant Mutations at the ATP-Dependent Potassium Channel SUR1 Subunit (ABCC8 Gene). Horm Res Paediatr. 2018; 90(2): 38-38

Cardon EB, Etxeberria IU, Elgarresta AA, Medina JM, Gonzales LC. Vitamin D Serum Levels and Associated Factors in a Healthy Child Population. Horm Res Paediatr. 2018; 90(2): 55-55

Viseras I, Mata M, Barea IT, Gonzalez LC. When Type Mody II Diabetes simulates Type I Diabetes. Horm Res Paediatr. 2018; 90(1): 272-273

Mata M, Viseras I, Barea IT, Gonzalez LC. Transient Neonatal Diabetes Mellitus Due to Not Described Mutation in ABCC8 Gene with Different Behaviour in Affected Family Members. Horm Res Paediatr. 2018; 90(1): 232-232

Knip M, Akerblom HK, Al Taji E, Becker D, Bruining J, Castano L, et al. Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes The TRIGR Randomized Clinical Trial. JAMA-J Am Med Assoc. 2018; 319(1): 38-48. DOI:10.1001/jama.2017.19826.

Hoey H, Lange K, Skinner TC, Mortensen H, Swift P, Aanstoot HJ, et al. Hvidoere Smiley Faces: International diabetes quality of life assessment tool for young children. Pediatr Diabetes. 2018; 19(3): 553-558. DOI:10.1111/pedi.12602.

Skinner TC, Lange KS, Hoey H, Mortensen HB, Aanstoot HJ, Castano L, et al. Targets and teamwork: Understanding differences in pediatric diabetes centers treatment outcomes. Pediatr Diabetes. 2018; 19(3): 559-565. DOI:10.1111/pedi.12606.

Garcia Castano A, Madariaga L, Azriel S, de Nanclares GP, de LaPiscina IM, Martinez R, et al. Identification of a novel large CASR deletion in a patient with familial hypocalciuric hypercalcemia. Endocrinol Diabetes Metab Case Rep. 2018. DOI:10.1530/EDM-18-0114.

Martinez E, Portillo N, Lizarralde E, Grau G, Vela A, Rodriguez A, et al. Paediatric T1DM: DKA is Still a Problem. Pediatr Endocrinol Rev PER. 2018; 16(2): 233-239. DOI:10.17458/per.vol16.2018.mpr.fd.t1dmdka.

Guerrero Fernandez J, San Julian C, Conde JB, de la Vega J, Urqui AC, Gonzalez L, et al. Management guidelines for disorders / different sex development (DSD). An Pediatr. 2018; 89(5). DOI:10.1016/j.anpedi.2018.06.009.

Gomez Peralta F, San Martin F, Torre EM, Cases MM, Garcia JCF, Loiola PE, et al. Spanish Diabetes Society (SED) recommendations for the pharmacologic treatment of hyperglycemia in type 2 diabetes: 2018 Update. Endocrinol Diabetes Nutr (Engl Ed). 2018; 65(10): 611-624. DOI:10.1016/j.endinu.2018.08.004.

Segura SA, Molina CT, Guindulain MJC, Bolado GG, Merillas M, Jaume MC, et al. Recommendations for the diagnosis and follow up of the foetus and newborn child born to mothers with autoimmune thyroid disease. An Pediatr. 2018; 89(4). DOI:10.1016/j.anpedi.2018.07.006.

Congregado DM, Aurrekoetxea I, Santos BG, de Urturi DS, Nunez M, Rodriguez JLG, et al. Involvement of the CREB-E2F2-PPAR axis in non-alcoholic fatty liver disease development and progression to hepatocarcinoma. J Hepatol. 2018; 68(1): 337-337. DOI:10.1016/S0168-8278(18)30893-6.

Borras JG, San Martin JE, Cases MM, Gomez Peralta F, Menendez SA, Garcia DF, et al. Consensus on insulin treatment in type 2 diabetes. Endocrinol Diabetes Nutr (Engl Ed). 2018; 65: 1-8. DOI:10.1016/j.endien.2018.01.003.

Ampuero J, Aller R, Gallego Duran R, Banales J, Crespo J, Mora Cuadrado N, et al. Clinical Outcomes in biopsy-proven NAFLD patients from the HEPAmet Spanish Registry. J Hepatol. 2018; 68: 833-833. DOI:10.1016/S0168-8278(18)31942-1.

Santos BG, Gonzalez Romero F, Nunez Garcia M, Congregado DM, de Urturi DS, de Juan VG, et al. During aging osteopontin deficiency increases vulnerability to non-alcoholic fatty liver disease progression and the associated extrahepatic metabolic complications. J Hepatol. 2018; 68: 360-360. DOI:10.1016/S0168-8278(18)30945-0.

Ampuero J, Aller R, Gallego Duran R, Banales J, Crespo J, Vilar Gomez E, et al. Hepamet Score: a new non-invasive method for NAFLD-related fibrosis screening in clinical practice. J Hepatol. 2018; 68: 97-98. DOI:10.1016/S0168-8278(18)30415-X.

Ampuero J, Aller R, Gallego Duran R, Banales J, Crespo J, Mora Cuadrado N, et al. Metabolically unhealthy status impacts on the risk of significant liver injury in biopsy-proven NAFLD patients beyond obesity. J Hepatol. 2018; 68: 832-833. DOI:10.1016/S0168-8278(18)31941-X.

Barbier Torres L, Delgado TC, Iruzubieta P, Ramos DF, de Juan VG, Varela Rey M, et al. The liver-specific deletion of the respiratory chain inhibitor MCJ attenuates NAFLD progression by enhancing hepatic beta-oxidation. J Hepatol. 2018; 68: 362-362. DOI:10.1016/S0168-8278(18)30949-8.

Simon J, Nunez M, Tussy PF, Barbier Torres L, Ramos DF, Santos BG, et al. Glutaminase 1 targeting in non-alcoholic steatohepatitis. J Hepatol. 2018; 68: 358-359. DOI:10.1016/S0168-8278(18)30942-5.

MADARIAGA DOMINGUEZ L, GARCIA CASTAÑO A, ARICETA IRAOLA MªG, MARTINEZ SALAZAR RM, AGUAYO CALCENA AA, CASTAÑO GONZALEZ LA. Variable phenotype in HNF1B mutations: extrarenal manifestations distinguish affected individuals from the population with congenital anomalies of the kidney and urinary tract. Clin Kidney J. 2019; 12(3): 373-379. DOI:10.1093/ckj/sfy102.

Fernández Ramos C, Arana Arri E, Jiménez Huertas P, Vela A, Rica I. Incidence of childhood-onset type 1 diabetes in Biscay, Spain, 1990-2013. Pediatr Diabetes. 2017; 18(1): 71-76. DOI:10.1111/pedi.12354.

Jiménez Fonseca P, Gómez Saez JM, Santamaria Sandi J, Capdevila J, Navarro Gonzalez E, Zafon Llopis C, et al. Spanish consensus for the management of patients with anaplastic cell thyroid carcinoma. Clin Transl Oncol. 2017; 19(1): 12-20. DOI:10.1007/s12094-016-1506-0.

Aguayo A, Urrutia I, González Frutos T, Martínez R, Martínez Indart L, Castaño L, et al. Prevalence of diabetes mellitus and impaired glucose metabolism in the adult population of the Basque Country, Spain. Diabetic Med. 2017; 34(5): 662-666. DOI:10.1111/dme.13181.

Capdevila J, Galofré JC, Grande E, Zafón Llopis C, Ramón Cajal Asensio YT, Navarro González E, et al. Consensus on the management of advanced radioactive iodine-refractory differentiated thyroid cancer on behalf of the Spanish Society of Endocrinology Thyroid Cancer Working Group (GTSEEN) and Spanish Rare Cancer Working Group (GETHI). Clin Transl Oncol. 2017; 19(3): 279-287. DOI:10.1007/s12094-016-1554-5.

Valdés S, Maldonado Araque C, Lago Sampedro A, Lillo JA, Garcia Fuentes E, Perez Valero V, et al. Population-Based National Prevalence of Thyroid Dysfunction in Spain and Associated Factors: Di@bet.es Study. Thyroid. 2017; 27(2): 156-166. DOI:10.1089/thy.2016.0353.

Velayos T, Martínez R, Alonso M, Garcia Etxebarria K, Aguayo A, Camarero C, et al. An Activating Mutation in STAT3 Results in Neonatal Diabetes Through Reduced Insulin Synthesis. Diabetes. 2017; 66(4): 1022-1029. DOI:10.2337/db16-0867.

Urrutia I, Martínez R, López Euba T, Velayos T, Martínez de LaPiscina I, Bilbao JR, et al. Lower Frequency of HLA-DRB1 Type 1 Diabetes Risk Alleles in Pediatric Patients with MODY. PLoS One. 2017; 12(1). DOI:10.1371/journal.pone.0169389.

Urrutia I, Martínez R, López Euba T, Velayos T, Martínez de LaPiscina I, Bilbao JR, et al. Lower Frequency of HLA-DRB1 Type 1 Diabetes Risk Alleles in Pediatric Patients with MODY. PLoS One. 2017; 12(1). DOI:10.1371/journal.pone.0169389.

Nucci AM, Virtanen SM, Sorkio S, Bärlund S, Cuthbertson D, Uusitalo U, et al. Regional differences in milk and complementary feeding patterns in infants participating in an international nutritional type 1 diabetes prevention trial. Matern Child Nutr. 2017; 13(3). DOI:10.1111/mcn.12354.

García Castaño A, Pérez de Nanclares G, Madariaga L, Aguirre M, Madrid Á, Chocrón S, et al. Poor phenotype-genotype association in a large series of patients with Type III Bartter syndrome. PLoS One. 2017; 12(3). DOI:10.1371/journal.pone.0173581.

Valdés S, Maldonado Araque C, Lago Sampedro A, Lillo Muñoz JA, Garcia Fuentes E, Perez Valero V, et al. Reference Values for TSH may be Inadequate to Define Hypothyroidism in Persons with Morbid Obesity: Di@bet.es Study. Obesity (Silver Spring). 2017; 25(4): 788-793. DOI:10.1002/oby.21796.

Hirschler V, González C, Maccallini G, Molinari C, Castano L, San Antonio de los Cobres Study Group C. Association between blood pressure and magnesium and uric acid levels in indigenous Argentinean children at high altitude. Am J Hum Biol. 2017; 29(4). DOI:10.1002/ajhb.22989.

Martínez R, Gutierrez Nogués Á, Fernández Ramos C, Velayos T, Vela A, Spanish Congenital Hyperinsulinism G, et al. Heterogeneity in phenotype of hyperinsulinism caused by activating glucokinase mutations: a novel mutation and its functional characterization. Clin Endocrinol (Oxf). 2017; 86(6): 778-783. DOI:10.1111/cen.13318.

Martínez R, Gutierrez Nogués Á, Fernández Ramos C, Velayos T, Vela A, Spanish Congenital Hyperinsulinism G, et al. Heterogeneity in phenotype of hyperinsulinism caused by activating glucokinase mutations: a novel mutation and its functional characterization. Clin Endocrinol (Oxf). 2017; 86(6): 778-783. DOI:10.1111/cen.13318.

Alonso C, Fernández Ramos D, Varela Rey M, Martínez Arranz I, Navasa N, Van Liempd SM, et al. Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis. Gastroenterology. 2017; 152(6): 1449-1449. DOI:10.1053/j.gastro.2017.01.015.

Zubiete Franco I, Fernández Tussy P, Barbier Torres L, Simon J, Fernández Ramos D, Lopitz Otsoa F, et al. Deregulated Neddylation in Liver Fibrosis. Hepatology. 2017; 65(2): 694-709. DOI:10.1002/hep.28933/suppinfo.

Santin I, Dos Santos RS, Marroqui L, Castellanos Rubio A, Velayos T, Jauregi Miguel A, et al. The type 1 diabetes candidate gene DEXI modulates virus-induced beta cell dysfunction via regulation of type I interferons. Diabetologia. 2017; 60(1): 204-205

Nunez Garcia M, Gomez Santos B, Buque X, Garcia Rodriguez JL, Romero MR, Marin JJG, et al. Osteopontin regulates the cross- talk between phosphatidylcholine and cholesterol metabolism in mouse liver. J Lipid Res. 2017; 58(9): 1903-1915. DOI:10.1194/jlr.M078980.

Martinez Sanchez N, Seoane Collazo P, Contreras C, Varela L, Villarroya J, Rial Pensado E, et al. Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance. Cell Metab. 2017; 26(1): 212-212. DOI:10.1016/j.cmet.2017.06.014.

Abulizi A, Perry RJ, Camporez JPG, Jurczak MJ, Petersen KF, Aspichueta P, et al. A controlled-release mitochondrial protonophore reverses hypertriglyceridemia, nonalcoholic steatohepatitis, and diabetes in lipodystrophic mice. FASEB J. 2017; 31(7): 2916-2924. DOI:10.1096/fj.201700001R.

Rica I, Mingorance A, Gomez Gila AL, Clemente M, Gonzalez I, Caimari M, et al. Achievement of metabolic control among children and adolescents with type 1 diabetes in Spain. Acta Diabetol. 2017; 54(7): 677-683. DOI:10.1007/s00592-017-0991-0.

Madariaga L, Herrero M, Aguirre M, Gondra L, Garcia N, Len JC, et al. Clinical manifestations and genotype-phenotype correlation in a cohort of patiens with mutations in the HNF1B gene. Pediatr Nephrol. 2017; 32(5): 905-905

Porteiro B, Fondevila MF, Delgado TC, Iglesias C, Imbernon M, Iruzubieta P, et al. Hepatic p63 regulates steatosis via IKK beta/ER stress. Nat Commun. 2017; 8: 15111-15111. DOI:10.1038/ncomms15111.

Clemente M, Campos A, Yeste D, Caimari M, Martinez Salazar R, Carrascosa A. DIABETES MELLITUS IN THE LONG-TERM FOLLOW-UP OF NON-PANCREATECTOMISED PATIENTS WITH PERSISTENT HYPERINSULINAEMIC HYPOGLYCAEMIA OF INFANCY DUE TO LOSS-OF-FUNCTION MUTATIONS IN THE ABCC8 GENE: A NEW FORM OF MONOGENIC DIABETES?. Horm Res Paediatr. 2017; 88(1): 37-37

Grau G, Aguayo A, Aniel Quiroga MA, Espada M, Miranda G, Vela A, et al. MATERNAL HYPOTHYROIDISM IN PREGNACY AND IMPACT ON THE MENTAL DEVELOPMENT OF THEIR CHILDREN. Horm Res Paediatr. 2017; 88(1): 214-214

Grau G, Aguayo A, Aniel Quiroga MA, Espada M, Miranda G, Vela A, et al. MATERNAL HYPOTHYROIDISM IN PREGNACY AND IMPACT ON THE MENTAL DEVELOPMENT OF THEIR CHILDREN. Horm Res Paediatr. 2017; 88(1): 214-214

Clemente M, Vargas A, Ariceta G, Martinez R, Campos A, Yeste D. Hyperinsulinaemic hypoglycaemia, renal Fanconi syndrome and liver disease due to a mutation in the HNF4A gene. Endocrinol Diabetes Metab Case Rep. 2017. DOI:10.1530/EDM-16-0133.

Varela M, Fernandez Ramos D, Iruarrizaga Lejarreta M, van Liempd S, DelaCruz Villar L, de Davalillo SL, et al. The effect of Aramchol on fibrosis is mediated by elevation of glutathione, improvement of fatty acid oxidation and maintenance of redox homeostasis. Hepatology. 2017; 66: 1087-1088

Lopez GP, Quispe BV, Nunez MJC, Castano L, Barrio R. Dysmorphic Features, Frontal Cerebral Cavernoma, and Hyperglycemia in a Girl with a De Novo Deletion of 7.23 Mb in Region 7p13-p12.1. J Clin Res Pediatr Endocrinol. 2017; 9(4): 355-359. DOI:10.4274/jcrpe.4324.

Varela Rey M, Fernandez Ramos D, Iruarrizaga Lejarreta M, Van Liempd SM, DelaCruz Villar L, de Davalillo SL, et al. Aramchol reduces established fibrosis in MCD diet animal model. J Hepatol. 2017; 66(1): 432-432. DOI:10.1016/S0168-8278(17)31232-1.

Iruarrizaga Lejarreta M, Varela Rey M, Fernández Ramos D, Martínez Arranz I, Delgado TC, Simon J, et al. Role of Aramchol in Steatohepatitis and Fibrosis in Mice. Hepatol Commun. 2017; 1(9): 911-927. DOI:10.1002/hep4.1107.

Estevez AR, Lopez ID, Galan IR, Guindulain MC, Rodriguez FJN. MULTICENTRIC STUDY OF METABOLIC CONTROL IN TYPE 1 DIABETES MELLITUS WITH THE USE OF FLASH GLUCOSE MONITORING SYSTEM AND DEGREE OF SATISFACTION. Horm Res Paediatr. 2017; 88(1): 611-612

Cabrera SM, Wang X, Chen Y, Jia S, Kaldunski ML, Greenbaum CJ, et al. Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset. Eur J Immunol. 2016; 46(4): 1030-1046. DOI:10.1002/eji.201546005.

Riesco Eizaguirre G, Galofré JC, Grande E, Zafón Llopis C, Ramón Cajal Asensio YT, Navarro González E, et al. Spanish consensus for the management of patients with advanced radioactive iodine refractory differentiated thyroid cancer. Endocrinol Nutr. 2016; 63(4). DOI:10.1016/j.endonu.2015.08.007.

Palomo Atance E, Bahíllo Curieses P, Bueno Lozano G, Feliu Rovira A, Gil Campos M, Lechuga Sancho AM, et al. Recommendations of the Spanish Paediatric Endocrinology Society Working Group on Obesity on eating habits for the prevention of obesity and cardiovascular risk factors in childhood. An Pediatr. 2016; 84(3): 178-178. DOI:10.1016/j.anpedi.2015.06.004.

Velayos T, Grau G, Rica I, Perez Nanclares G, Gaztambide S. Glucocorticoid resistance syndrome caused by two novel mutations in the NR3C1 gene. Endocrinol Nutr. 2016; 63(7): 369-371. DOI:10.1016/j.endonu.2016.03.010.

Velayos T, Grau G, Rica I, Perez Nanclares G, Gaztambide S. Glucocorticoid resistance syndrome caused by two novel mutations in the NR3C1 gene. Endocrinol Nutr. 2016; 63(7): 369-371. DOI:10.1016/j.endonu.2016.03.010.

Grande E, Santamaria Sandi J, Capdevila J, Navarro Gonzalez E, Zafon Llopis C, Ramon y Cajal Asensio T, et al. Consensus on management of advanced medullary thyroid carcinoma on behalf of the Working Group of Thyroid Cancer of the Spanish Society of Endocrinology (SEEN) and the Spanish Task Force Group for Orphan and Infrequent Tumors (GETHI). Clin Transl Oncol. 2016; 18(8): 769-775. DOI:10.1007/s12094-015-1465-x.

Martinez R, Fernandez Ramos C, Vela A, Velayos T, Aguayo A, Urrutia I, et al. Clinical and genetic characterization of congenital hyperinsulinism in Spain. Eur J Endocrinol. 2016; 174(6): 717-726. DOI:10.1530/EJE-16-0027.

Martinez R, Fernandez Ramos C, Vela A, Velayos T, Aguayo A, Urrutia I, et al. Clinical and genetic characterization of congenital hyperinsulinism in Spain. Eur J Endocrinol. 2016; 174(6): 717-726. DOI:10.1530/EJE-16-0027.

Bellido V, Larranaga I, Guimon M, Martinez Conde R, Eguia A, Perez de Nanclares G, et al. A Novel Mutation in a Patient with Hyperparathyroidism-Jaw Tumour Syndrome. Endocr Pathol. 2016; 27(2): 142-146. DOI:10.1007/s12022-016-9427-6.

Zubiete Franco I, Garcia Rodriguez JL, Martinez Una M, Martinez Lopez N, Woodhoo A, Gutierrez De Juan V, et al. Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis. J Hepatol. 2016; 64(2): 409-418. DOI:10.1016/j.jhep.2015.08.037.

Garcia Ariza M, Portillo Najera N, Gonzalez Camacho U, Rubio Rojas R, Vela De Sojo A, Rica I, et al. 10 YEARS REVIEW OF ENDOCRINOLOGICAL LATE EFFECTS IN SPANISH PATIENTS WITH PRIMARY BRAIN TUMORS IN A TERTIARY HOSPITAL. Neuro-Oncology. 2016; 18(3): 151-151

Luque RM, Ibanez Costa A, Sanchez Tejada L, Rivero Cortes E, Robledo M, Madrazo Atutxa A, et al. The Molecular Registry of Pituitary Adenomas (REMAH): A bet of Spanish Endocrinology for the future of individualized medicine and translational research. Endocrinol Nutr. 2016; 63(6): 274-284. DOI:10.1016/j.endonu.2016.03.001.

Menendez E, Delgado E, Fernandez Vega F, Prieto MA, Bordiu E, Calle A, et al. Prevalence, Diagnosis, Treatment, and Control of Hypertension in Spain. Results of the Di@bet.es Study. Rev Esp Cardiol. 2016; 69(6): 572-578. DOI:10.1016/j.rec.2015.11.034.

Julliand S, Desmarest M, Gonzalez L, Ballestero Y, Martinez A, Moretti R, et al. Recovery position significantly associated with a reduced admission rate of children with loss of consciousness. Arch Dis Child. 2016; 101(6): 521-526. DOI:10.1136/archdischild-2015-308857.

Maria Sanchez Hernandez R, Martin Frias M, Castano L, Lamas A, Barrio R. Donohue syndrome. Extreme insulin resistance in the neonatal period. Endocrinol Nutr. 2016; 63(1): 45-46. DOI:10.1016/j.endonu.2015.10.002.

Chico A, Herranz L, Corcoy R, Ramirez O, Goya MM, Bellart J, et al. Glycemic control and maternal and fetal outcomes in pregnant women with type 1 diabetes according to the type of basal insulin. Eur J Obstet Gynecol Reprod Biol. 2016; 206: 84-91. DOI:10.1016/j.ejogrb.2016.07.490.

Brugnara L, Murillo S, Novials A, Rojo Martinez G, Soriguer F, Goday A, et al. Low Physical Activity and Its Association with Diabetes and Other Cardiovascular Risk Factors: A Nationwide, Population-Based Study. PLoS One. 2016; 11(8). DOI:10.1371/journal.pone.0160959.

Echebarria A, Garcia N, De Pedro J, Gonzalez U, Garcia Obregon S, Capape S, et al. Metabolic Complications During Induction Therapy in Children with Acute Lymphoblastic Leukemia. Pediatr Blood Cancer. 2016; 63(3): 104-105

Martinez R, Ortiz Espejo M, Aguayo A, Velayos T, Urrutia I, MARTINEZ DE LAPISCINA MARTIN I, et al. Genotype-Phenotype Correlation in Severe Insulin Resistance Syndromes: 5 Cases with Recessive Mutations in INSR. Horm Res Paediatr. 2016; 86(2): 13-13

Martinez R, Ortiz Espejo M, Aguayo A, Velayos T, Urrutia I, MARTINEZ DE LAPISCINA MARTIN I, et al. Genotype-Phenotype Correlation in Severe Insulin Resistance Syndromes: 5 Cases with Recessive Mutations in INSR. Horm Res Paediatr. 2016; 86(2): 13-13

Gonzalez Frutos T, Calleja C, Castano L, Blarduni F, GOIVIDE GRP. Nutritional Quality of Diets of Children from One Area of the Basque Country (Spain). Horm Res Paediatr. 2016; 86(2): 84-84

Mera Gallego R, Garcia Rodriguez P, Fernandez Cordeiro M, Rodriguez Reneda A, Verez Cotelo N, Andres Rodriguez NF, et al. Cardiovascular risk factors in scholars (RIVACANGAS). Endocrinol Nutr. 2016; 63(10): 511-518. DOI:10.1016/j.endonu.2016.07.005.

Ballestero Y, De Pedro J, Portillo N, Martinez Mugica O, Arana E, Zazo N, et al. PILOT CLINICALTRIAL OF THE USE OF OXYGEN AT HIGH FLOW IN CHILDREN WITH ASTHMA IN THE PEDIATRIC EMERGENCY SERVICE. Eur J Pediatr. 2016; 175(11): 1511-1512

Santos Mata MA, Fernandez Viseras I, Torres Barea I, Macias Lopez FJ, Catano L. Permanent Neonatal Diabetes by Gene Mutation KCNJ11. Evolution and Treatment after Three Years with Sulphonylureas. Horm Res Paediatr. 2016; 86(1): 236-237

Grau G, Portillo N, Lopez Almaraz R, Echebarria A, Adan R, Rodriguez A, et al. Severe Hypertriglyceridemia in Pediatric Oncology Patient. Horm Res Paediatr. 2016; 86(1): 301-302

Portillo N, Gonzalez U, Rubio R, Garcia Ariza M, Grau G, Vela A, et al. 10 Years Review of Endocrine Diseases in Spanish Patients Diagnosed with Primary Brain Tumors in a Tertiary Hospital. Horm Res Paediatr. 2016; 86(1): 433-433

Conget I, Mauricio D, Ortega R, Detournay B, CHADIG Study I. Characteristics of patients with type 2 diabetes mellitus newly treated with GLP-1 receptor agonists (CHADIG Study): a cross-sectional multicentre study in Spain. Bmj Open. 2016; 6(7). DOI:10.1136/bmjopen-2015-010197.

Nuño Solinís R, Alonso Morán E, Arteagoitia Axpe JM, Ezkurra Loiola P, Orueta JF, Gaztambide S. Healthcare costs of people with type 2 diabetes mellitus in the Basque Country (Spain). Endocrinol Nutr. 2016; 63(10): 543-550. DOI:10.1016/j.endonu.2016.08.003.

Kaur S, Mirza AH, Brorsson CA, Floyel T, Storling J, Mortensen HB, et al. The genetic and regulatory architecture of ERBB3-type I diabetes susceptibility locus. Mol Cell Endocrinol. 2016; 419(C): 83-91. DOI:10.1016/j.mce.2015.10.002.

Santin I, Dos Santos RS, Eizirik DL. Pancreatic Beta Cell Survival and Signaling Pathways: Effects of Type 1 Diabetes-Associated Genetic Variants. Methods Mol Biol. 2016; 1433: 21-54. DOI:10.1007/7651_2015_291.

RICA ETXEBARRIA I. Guía de atención integral a las personas en situación de transexualidad. Guías de Práctica Clínica. 2016

Rouco I, Hurtado P, Castaño L, Zarranz JJ. Experience with imnnunotherapy in 3 patients with cerebellar ataxia associated with anti-glutamic acid decarboxylase antibodies. Neurologia. 2015; 30(4): 247-249. DOI:10.1016/j.nrl.2013.06.018.

Ramírez Domínguez M, Castaño L. Filtration is a time-efficient option to Histopaque, providing good-quality islets in mouse islet isolation. Cytotechnology. 2015; 67(2): 199-206. DOI:10.1007/s10616-014-9690-7.

Perez Nanclares G, Velayos T, Vela A, Muñoz Torres M, Castaño L. Pseudohypoparathyroidism Type Ib Associated with Novel Duplications in the GNAS Locus. PLoS One. 2015; 10(2). DOI:10.1371/journal.pone.0117691.

Perez Nanclares G, Velayos T, Vela A, Muñoz Torres M, Castaño L. Pseudohypoparathyroidism Type Ib Associated with Novel Duplications in the GNAS Locus. PLoS One. 2015; 10(2). DOI:10.1371/journal.pone.0117691.

Martínez Uña M, Varela Rey M, Mestre D, Fernández Ares L, Fresnedo O, Fernandez Ramos D, et al. S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease. J Hepatol. 2015; 62(3): 673-681. DOI:10.1016/j.jhep.2014.10.019.

Grau G, Aguayo A, Vela A, Aniel Quiroga A, Espada M, Miranda G, et al. Normal intellectual development in children born from women with hypothyroxinemia during their pregnancy. J Trace Elem Med Biol. 2015; 31: 18-24. DOI:10.1016/j.jtemb.2015.02.004.

Grau G, Aguayo A, Vela A, Aniel Quiroga A, Espada M, Miranda G, et al. Normal intellectual development in children born from women with hypothyroxinemia during their pregnancy. J Trace Elem Med Biol. 2015; 31: 18-24. DOI:10.1016/j.jtemb.2015.02.004.

Jesus Amor A, Masana L, Soriguer F, Goday A, Calle Pascual A, Gaztambide S, et al. Estimating Cardiovascular Risk in Spain by the European Guidelines on Cardiovascular Disease Prevention in Clinical Practice. Rev Esp Cardiol. 2015; 68(5): 417-425. DOI:10.1016/j.rec.2014.05.023.

Alonso Moran E, Orueta JF, Fraile Esteban JI, Arteagoitia Axpe JM, Luz Marques Gonzalez MA, Toro Polanco N, et al. Multimorbidity in people with type 2 diabetes in the Basque Country (Spain): Prevalence, comorbidity clusters and comparison with other chronic patients. Eur J Intern Med. 2015; 26(3): 197-202. DOI:10.1016/j.ejim.2015.02.005.

Valdes N, Navarro E, Mesa J, Casteras A, Alcazar V, Lamas C, et al. RET Cys634Arg mutation confers a more aggressive multiple endocrine neoplasia type 2A phenotype than Cys634Tyr mutation. Eur J Endocrinol. 2015; 172(3): 301-307. DOI:10.1530/EJE-14-0818.

Barbier Torres L, Delgado TC, Garcia Rodriguez JL, Zubiete Franco I, Fernandez Ramos D, Buque X, et al. Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer. Oncotarget. 2015; 6(4): 2509-2523. DOI:10.18632/oncotarget.3191.

Rodriguez Estevez A, Perez Nanclares G, Fernandez Toral J, Rivas Crespo F, Lopez Siguero JP, Diez I, et al. Clinical and molecular characterization of five Spanish kindreds with X-linked adrenal hypoplasia congenita: atypical findings and a novel mutation in NR0B1. J Pediatr Endocrinol Metab. 2015; 28(9-10): 1129-1137. DOI:10.1515/jpem-2014-0472.

Rodriguez Estevez A, Perez Nanclares G, Fernandez Toral J, Rivas Crespo F, Lopez Siguero JP, Diez I, et al. Clinical and molecular characterization of five Spanish kindreds with X-linked adrenal hypoplasia congenita: atypical findings and a novel mutation in NR0B1. J Pediatr Endocrinol Metab. 2015; 28(9-10): 1129-1137. DOI:10.1515/jpem-2014-0472.

Falorni A, Bini V, Betterle C, Brozzetti A, Castano L, Fichna M, et al. Determination of 21-hydroxylase autoantibodies: inter-laboratory concordance in the Euradrenal International Serum Exchange Program. Clin Chem Lab Med. 2015; 53(11): 1761-1770. DOI:10.1515/cclm-2014-1106.

Perez Ruiz F, Pamela Chinchilla S, Atxotegi J, Urionagueena I, Maria Herrero Beites A, Angeles Aniel Quiroga M. Increase in thyroid stimulating hormone levels in patients with gout treated with inhibitors of xanthine oxidoreductase. Rheumatol Int. 2015; 35(11): 1857-1861. DOI:10.1007/s00296-015-3355-5.

Garcia Castano A, Perez de Nanclares G, Madariaga L, Aguirre M, Chocron S, Madrid A, et al. Novel mutations associated with nephrogenic diabetes insipidus. A clinical-genetic study. Eur J Pediatr. 2015; 174(10): 1373-1385. DOI:10.1007/s00431-015-2534-4.

Perez Ruiz F, Angeles Aniel Quiroga M, Maria Herrero Beites A, Pamela Chinchilla S, Garcia Erauskin G, Merriman T. Renal clearance of uric acid is linked to insulin resistance and lower excretion of sodium in gout patients. Rheumatol Int. 2015; 35(9): 1519-1524. DOI:10.1007/s00296-015-3242-0.

Gomez Sanchez JA, Carty L, Iruarrizaga Lejarreta M, Palomo Irigoyen M, Varela Rey M, Griffith M, et al. Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves. J Cell Biol. 2015; 210(1): 153-168. DOI:10.1083/jcb.201503019.

Marroqui L, Dos Santos RS, Floyel T, Grieco FA, Santin I, de Beeck AO, et al. TYK2, a Candidate Gene for Type 1 Diabetes, Modulates Apoptosis and the Innate Immune Response in Human Pancreatic beta-Cells. Diabetes. 2015; 64(11): 3808-3817. DOI:10.2337/db15-0362.

Marroqui L, Dos Santos RS, Floyel T, Santin I, de Beeck A, Marselli L, et al. TYK2, a candidate gene for type 1 diabetes, modulates apoptosis and the innate immune response in human pancreatic beta cells. Diabetologia. 2015; 58(1): 45-45

Rios Orbananos I, Vela Desojo A, Martinez Indart L, Grau Bolado G, Rodriguez Estevez A, Rica Echevarria I. Turner syndrome: From birth to adulthood. Endocrinol Nutr. 2015; 62(10): 499-506. DOI:10.1016/j.endonu.2015.06.010.

Nuñez Rodriguez FJ, García Barcina MJ, Martinez De Lizarduy I, Fernandez Ramos C, Sanchez Gonzalez E. Sitosterolemia in a 2 year-old child with xanthomas and hematological anomalies. An Pediatr. 2015; 82(3): 209-210. DOI:10.1016/j.anpedi.2014.06.012.

Alonso Moran E, Orueta JF, Fraile Esteban JI, Arteagoitia Axpe JM, Marques Gonzalez ML, Toro Polanco N, et al. Prevalence and quality of care indicators of type 2 diabetes in the population of the Basque Country (Spain). Av Diabetol. 2015; 31(2): 72-79. DOI:10.1016/j.avdiab.2015.01.002.

Menendez Torre E, Gaztambide S, Rica I, Castano L, Javier Salvador F, Javier Escalada F. MIPDI-1 project. Agreement on the integrated management of patients with type 1 diabetes mellitus. Av Diabetol. 2015; 31(1): 13-23. DOI:10.1016/j.avdiab.2014.10.005.

Menendez Torre E, Gaztambide S, Rica I, Castano L, Javier Salvador F, Javier Escalada F. MIPDI-1 project. Agreement on the integrated management of patients with type 1 diabetes mellitus. Av Diabetol. 2015; 31(1): 13-23. DOI:10.1016/j.avdiab.2014.10.005.

Neu A, Lange K, Barrett T, Cameron F, Dorchy H, Hoey H, et al. Classifying insulin regimens-difficulties and proposal for comprehensive new definitions. Pediatr Diabetes. 2015; 16(6): 402-406. DOI:10.1111/pedi.12275.

Onengut Gumuscu S, Chen W, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, et al. Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. Nat Genet. 2015; 47(4): 381-199. DOI:10.1038/ng.3245.

Galofré JC, Santamaría Sandi J, Capdevila J, Navarro González E, Zafón Llopis C, Ramón Cajal Asensio YT, et al. Consensus on the management of advanced medullary thyroid carcinoma on behalf of the Working Group of Thyroid Cancer of the Spanish Society of Endocrinology (SEEN) and the Spanish Task Force Group for Orphan and Infrequent Tumors (GETHI). Endocrinol Nutr. 2015; 62(4). DOI:10.1016/j.endonu.2015.01.005.

Gómez Sáez JM, Jiménez Fonseca P, Santamaría Sandi J, Capdevila Castillón J, Navarro González E, Zafón Llopis C, et al. Spanish consensus for the management of patients with anaplastic cell thyroid carcinoma. Endocrinol Nutr. 2015; 62(3). DOI:10.1016/j.endonu.2014.11.006.

Mata Cases M, Artola S, Escalada J, Ezkurra Loyola P, Ferrer García JC, Fornos JA, et al. Consensus on the detection and management of prediabetes. Consensus and Clinical Guidelines Working Group of the Spanish Diabetes Society. Rev Clin Esp. 2015; 215(2): 117-129. DOI:10.1016/j.rce.2014.10.012.

Hirschler V, Molinari C, Maccallini G, Sanchez M, Gonzalez C, On Behalf Of San Antonio de Los Cobres Study Group Collaborators Graciela C, et al. Status of Dyslipidemia in Vitamin D Supplemented Argentinean Indigenous Children Versus A Non-supplemented Mixed Population Group. Cardiovasc Hematol Agents Med Chem. 2015; 13(2): 129-136

Mata Cases M, Artola S, Escalada J, Ezkurra Loyola P, Ferrer García JC, Fornos JA, et al. Consenso sobre la detección y el manejo de la prediabetes. Grupo de Trabajo de Consensos y Guías Clínicas de la Sociedad Española de Diabetes. Semergen. 2015; 41(5): 266-278. DOI:10.1016/j.semerg.2014.12.001.

Ochoa E, Lee S, Lan Leung B, Dias RP, Ong KK, Radley JA, et al. ImprintSeq, a novel tool to interrogate DNA methylation at human imprinted regions and diagnose multilocus imprinting disturbance. Genet Med. 2022; 24(2): 463-474. DOI:10.1016/j.gim.2021.10.011.

Ruiz de Gauna M, Biancaniello F, Gonzalez Romero F, Rodrigues PM, Lapitz A, Gomez Santos B, et al. Cholangiocarcinoma progression depends on the uptake and metabolization of extracellular lipids. Hepatology. 2022; 76(6): 1617-1633. DOI:10.1002/hep.32344.

Jebari Benslaiman S, Uribe KB, Benito Vicente A, Galicia Garcia U, Larrea Sebal A, Santin I, et al. Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple-Cell 2D Atherosclerosis Model. Small. 2022; 18(13). DOI:10.1002/smll.202105915.

Sot J, Garcia Arribas AB, Abad B, Arranz S, Portune K, Andrade F, et al. Erythrocyte Membrane Nanomechanical Rigidity Is Decreased in Obese Patients. Int J Mol Sci. 2022; 23(3). DOI:10.3390/ijms23031920.

Vazquez Mosquera ME, Gonzalez Vioque E, Barbosa Gouveia S, Bellido Guerrero D, Tejera Perez C, Martinez Olmos MA, et al. Transcriptomic analysis of patients with clinical suspicion of maturity-onset diabetes of the young (MODY) with a negative genetic diagnosis. Orphanet J Rare Dis. 2022; 17(1). DOI:10.1186/s13023-022-02263-3.

Saenz de Urturi D, Buque X, Porteiro B, Folgueira C, Mora A, Delgado TC, et al. Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis. Nat Commun. 2022; 13(1): 1096-1096. DOI:10.1038/s41467-022-28749-z.

Olaizola P, Lee Law PY, Fernandez Barrena MG, Alvarez L, Cadamuro M, Azkargorta M, et al. Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models. J Hepatol. 2022; 77(1): 177-190. DOI:10.1016/j.jhep.2022.02.007.

Gomez Munoz L, Perna Barrull D, Caroz Armayones JM, Murillo M, Rodriguez Fernandez S, Valls A, et al. Candidate Biomarkers for the Prediction and Monitoring of Partial Remission in Pediatric Type 1 Diabetes. Front Immunol. 2022; 13. DOI:10.3389/fimmu.2022.825426.

Ochoa E, Lee S, Lan Leung B, Dias R, Ong KK, Radley JA, et al. New diagnostic tool for multi-locus imprinting disturbances. Eur J Hum Genet. 2022; 30(SUPPL 1): 549-550

Moral Martos A, Guerrero Fernandez J, Gomez Balaguer M, Rica Echevarria I, Campos Martorell A, Chueca Guindulain MJ, et al. Clinical practice guidelines for transsexual, transgender and gender diverse minors. An Pediatr (Engl Ed). 2022; 96(4): 3491-34911. DOI:10.1016/j.anpede.2022.02.002.

Castano L, Madariaga L, Grau G, Garcia Castano A. 25(OH)Vitamin D Deficiency and Calcifediol Treatment in Pediatrics. Nutrients. 2022; 14(9). DOI:10.3390/nu14091854.

Exposito Rodriguez A, Corta Gomez I, Dominguez Ayala M, Garcia Carrillo M, Gonzalez Garcia AI, Gutierrez Rodriguez MT, et al. Sentinel lymph node biopsy in papillary thyroid cancer: Accuracy and application in clinical practice. Cir Esp (Engl Ed). 2022; 100(7): 416-421. DOI:10.1016/j.cireng.2022.04.022.

Olaizola P, Rodrigues PM, Caballero Camino FJ, Izquierdo Sanchez L, Aspichueta P, Bujanda L, et al. Genetics, pathobiology and therapeutic opportunities of polycystic liver disease. Nat Rev Gastroenterol Hepatol. 2022; 19(9): 585-604. DOI:10.1038/s41575-022-00617-7.

Nowak C, Lind M, Sumnik Z, Pelikanova T, Chavez LN, Lundberg E, et al. Intralymphatic GAD-alum (Diamyd) improves glycaemic control in Type 1 diabetes with HLA DR3-DQ2. J Clin Endocrinol Metab. 2022; 107(9): 2644-2651. DOI:10.1210/clinem/dgac343.

Gonzalez Fenandez M, Antonio IED, Martin IMP, Martinez JS, Almaraz MCA. 5-Alpha-reductase type 2 deficiency. A new case in the Spanish population. Endocrinol Diabetes Nutr (Engl Ed). 2022; 69(5): 384-386. DOI:10.1016/j.endien.2021.04.002.

Cruz R, Almeida SD, Heredia ML, Quintela I, Ceballos FC, Pita G, et al. Novel genes and sex differences in COVID-19 severity. Hum Mol Genet. 2022. DOI:10.1093/hmg/ddac132.

Labiano I, Agirre Lizaso A, Olaizola P, Echebarria A, Huici Izagirre M, Olaizola I, et al. TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation. J Hepatol. 2022; 77(4): 991-1004. DOI:10.1016/j.jhep.2022.05.044.

Garcia Perez J, Gonzalez Perez M, Castillo de la Osa M, Borobia AM, Castano L, Bertran MJ, et al. Immunogenic dynamics and SARS-CoV-2 variant neutralisation of the heterologous ChAdOx1-S/BNT162b2 vaccination: Secondary analysis of the randomised CombiVacS study. Eclinicalmedicine. 2022; 50: 101529-101529. DOI:10.1016/j.eclinm.2022.101529.

Ruiz de Gauna M, Biancaniello F, Gonzalez Romero F, Miguel Rodrigues P, Lapitz A, Gomez Santos B, et al. The uptake of extracellular lipids promotes cholangiocarcinoma progression. J Hepatol. 2022; 77: 648-648

Del Barrio Azaceta M, Iruzubieta P, Aller de la Fuente R, Maria Banales J, Santos Laso A, Calleja Panero JL, et al. The metabolic dysfunction-associated fatty liver disease definition, regardless of its clinical subclassification, identifies patients at high risk for liver disease progression. J Hepatol. 2022; 77: 158-159

Gomez Santos B, Fernamdez Puertas I, Nieva Zuluaga A, Ruiz de Gauna M, Apodaka Biguri M, Gonzalez Romero F, et al. The DNA damage response is involved in the metabolic dysregulation of MAFLD patients via inefficient fatty acid oxidation. J Hepatol. 2022; 77: 665-665

Olaizola P, Lee Law P, Fernandez Barrena MG, Alvarez L, Cadamuro M, Azkargorta M, et al. Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumour-stroma crosstalk in experimental models. J Hepatol. 2022; 77: 46-46

Apodaka Biguri M, Gonzalez Romero F, Mestre Congregado D, Aurrekoetxea I, Gomez Santos B, Delgado I, et al. miR34a-5p is a target of E2F2 transcription factor in MAFLD-related HCC. J Hepatol. 2022; 77: 651-652

Buque X, Saenz de Urturi D, Porteiro B, Folgueira C, Mora A, Cardoso Delgado T, et al. Methionine adenosyltransferase 1a antisense oligonucleotides induce the fibroblast growth factor 21-driven recovery from obesity and associated hepatoesteatosis. J Hepatol. 2022; 77: 689-690

Del Barrio Azaceta M, Iruzubieta P, Aller De La Fuente R, Maria Banales J, Santos Laso A, Calleja Panero JL, et al. Metabolic dysfunction-associated fatty liver disease increases cardiovascular risk regardless of classical risk factors. J Hepatol. 2022; 77: 157-157

Vallejo Casas JA, Sambo M, Lopez C, Duran Poveda M, Rodriguez Villanueva Garcia J, Santos RJ, et al. Initial clinical and treatment patterns of advanced differentiated thyroid cancer: ERUDIT study. Eur Thyroid J. 2022; 11(5). DOI:10.1530/ETJ-21-0111.

Diez JJ, Anda E, Alcazar V, Isidro ML, Familiar C, Paja M, et al. Differentiated thyroid carcinoma in the elderly: influence of age on disease-free and overall survival. Endocrine. 2022; 77(1): 121-133. DOI:10.1007/s12020-022-03059-y.

Valdes S, Doulatram Gamgaram V, Maldonado Araque C, Lago Sampedro A, Garcia Escobar E, Garcia Serrano S, et al. Ambient air pollution and thyroid function in Spanish adults. A nationwide population-based study (Di@bet.es study). Environ Health. 2022; 21(1). DOI:10.1186/s12940-022-00889-1.

Lago Sampedro A, Lhamyani S, Valdes S, Colomo N, Maldonado Araque C, Gonzalez Molero I, et al. Serum vascular endothelial growth factor b and metabolic syndrome incidence in the population based cohort Di@bet.es study. Int J Obes. 2022; 46(11): 2013-2020. DOI:10.1038/s41366-022-01212-1.

Garcia E, Alvarez Del Vayo C, Castano L. Familial male-limited precocious puberty (testotoxicosis): Usefulness of treatment with ketoconazole and triptorelin. Med Clin. 2022; 159(11): 79-80. DOI:10.1016/j.medcli.2022.08.007.

Kouri C, Sommer G, Martinez de LaPiscina I, Tack L, Cools M, Flueck CE. The international SF1 next project: Description of a cohort of 107 individuals with SF-1/NR5A1 variants. Sex Dev. 2022; 16(SUPPL 1): 23-24

Martinez de LaPiscina I, Kouri C, Sommer G, Tack L, Cools M, Flueck CE, et al. Spectrum of SF-1/NR5A1 gene variants in the large international SF1next cohort. Sex Dev. 2022; 16(SUPPL 1): 65-66

Garcia Castano A, Gomez Conde S, Madariaga L, Ariceta G. NEW FAMILY WITH KCNJ16 GENE TUBULOPATHY, CHARACTERIZED BY HYPOKALEMIA, IMPAIRED ACID-BASE HOMEOSTASIS AND SENSORINEURAL HEARING LOSS. Pediatr Nephrol. 2022; 37(11): 2874-2875

Mendizabal L, Arregi M, Deogracia JV, Levi AMR, Barabash A, De la Torre NG, et al. New Gestational Diabetes Mellitus Risk Algorithm. Diabetes. 2022; 71. DOI:10.2337/db22-156-LB.

Biagetti B, Iglesias P, Villar Taibo R, Moure M, Paja M, Araujo Castro M, et al. Factors associated with therapeutic response in acromegaly diagnosed in the elderly in Spain. Front Endocrinol. 2022; 13: 984877-984877. DOI:10.3389/fendo.2022.984877.

Hamidi M, Eriz A, Mitxelena J, Fernandez Ares L, Aurrekoetxea I, Aspichueta P, et al. Targeting E2F Sensitizes Prostate Cancer Cells to Drug-Induced Replication Stress by Promoting Unscheduled CDK1 Activity. Cancers (Basel). 2022; 14(19). DOI:10.3390/cancers14194952.

de LaPiscina IM, Kouri C, Sommer G, Tack L, Cools M, Fluck C, et al. SF1next study: spectrum of SF-1/NR5A1 gene variants in this large international cohort. Horm Res Paediatr. 2022; 95(SUPPL 2): 109-109

Grau G, Andrade F, Vela A, Lopez Oceja R, Rica I. Bisphenol A (BPA): A hidden enemy. Horm Res Paediatr. 2022; 95(SUPPL 2): 536-536

Kouri C, Sommer G, Martinez de LaPiscina I, Tack L, Cools M, Fluck CE, et al. Phenotypes in a large international cohort of individuals with SF-1/NR5A1 variants. Horm Res Paediatr. 2022; 95(SUPPL 2): 46-46

Marcelo I, Urrutia I, Calvo B, Martinez R, Saso L, Castano L, et al. Prevalence of autoimmunity in relatives of patients with type 1 diabetes: Time to the clinical onset of diabetes and associated risk factors. Horm Res Paediatr. 2022; 95(SUPPL 2): 177-178

Hirschler V, Gonzalez CD, Itxaso R, Ines U, Zalazar Rosa M, Anibal A, et al. Association between Hepcidin and Type 2 Diabetes markers In Indigenous Argentinean Children living at High Altitude. Clin Chim Acta. 2022; 537: 194-198. DOI:10.1016/j.cca.2022.08.021.

Nunez Munoz R, Ortega YC, Sarmiento M, Jorge RV, Fuentes AP, Subirats JG, et al. Stimulated thyroglobulin ( TG) prior to [131I] therapy (RAIT) in patients with differentiated thyroid cancer (DTC) as a predictive factor of recurrence. Eur J Nucl Med Mol Imaging. 2022; 49(SUPPL 1): 586-586

Martin Fernandez M, Arroyo V, Carnicero C, Siguenza R, Busta R, Mora N, et al. Role of Oxidative Stress and Lipid Peroxidation in the Pathophysiology of NAFLD. Antioxidants. 2022; 11(11). DOI:10.3390/antiox11112217.

Guerrero Fernandez J, Gonzalez Peramato P, Rodriguez Estevez A, Alcazar Villar MJ, Audi Parera L, Azcona San Julian MC, et al. Consensus guide on prophylactic gonadectomy in different sex development. Endocrinol Diabetes Nutr (Engl Ed). 2022. DOI:10.1016/j.endien.2022.10.002.

Velasco I, Vila L, Goya M, Oleaga A, de la Calle M, Santamaria FJ. Executive summary of the SEEN (Sociedad Espanola de Endocrinologia y Nutricion[Spanish Society of Endocrinology and Nutrition])-SEGO (Sociedad Espanola deGinecologia y Obstetricia [Spanish Society of Gynaecology and Obstetrics]) consensusdocument on the management of thyroid dysfunction during pregnancy. Endocrinol Diabetes Nutr (Engl Ed). 2022. DOI:10.1016/j.endien.2022.11.008.

Aguayo A, Grau G, Vela A, Aniel-Quiroga A, Espada M, Martul P, et al. Urinary iodine and thyroid function in a population of healthy pregnant women in the North of Spain. J. Trace Elem Med Biol. 2013;27:302-6. FI: 1,959(Q3)

Aguayo A, Vela A, Aniel-Quiroga A, Blarduni E, Fernandez C, Grau G, et al. Absence of diabetes mellitus type 2 in obese children and adolescents in the north of Spain. J Pediatr Endocrinol Metab. 2013;26:25-9. FI: 0,747(Q4)

Arisqueta L, Nuñez-Garcia M, Ogando J, Garcia-Arcos I, Ochoa B, Aspichueta P, et al. Involvement of lipid droplets in hepatic responses to lipopolysaccharide treatment in mice.Biochim.Biophys. Acta Mol Cell Biol Lipids. 2013;1831:1357-67. FI: 4,134(Q1)

Cameron FJ, de Beaufort C, Aanstoot HJ, Hoey H, Lange K, Castano L, et al: Hvidoere Int Study Grp. Lessons from the Hvidoere International Study Group on childhood diabetes: be dogmatic about outcome and flexible in approach. Pediatr Diabetes. 2013;14:473-80. FI: 2,077(Q2)

de Beaufort CE, Lange K, Swift PG, Aman J, Cameron F, Castano L, et al; Hvidoere Study Group. Metabolic outcomes in young children with type 1 diabetes differ between treatment centers: the Hvidoere Study in Young Children 2009. Pediatr Diabetes. 2013;14:422-8. FI: 2,077(Q2)

Dominguez Garcia A, Castano Gonzalez LA, Perez-Nanclares G, Quinteiro Gonzalez S, Caballero Fernandez E. Clinical features of two cases of pseudohypoparathyroidism (la and lb) and molecular analysis of GNAS. An Pediatr. 2013;79:319-24. FI: 0,867(Q3)

Elhayek D, Perez de Nanclares G, Chouchane S, Hamami S, Mlika A, Troudi M, et al. Molecular diagnosis of distal renal tubular acidosis in Tunisian patients: proposed algorithm for Northern Africa populations for the ATP6V1B1, ATP6V0A4 and SCL4A1 genes. BMC Med Genet. 2013;14:119. FI: 2,536(Q3)

Esmatjes E, Jansa M, Roca D, Perez N, Martinez S, Ruiz de Adana M, et al. The efficiency of telemedicine to optimise metabolic control in patients with type 1 diabetes mellitus. Diabetologia. 2013;56: 451. FI: 6,487(Q1)

Esteva de Antonio I, Gómez-Gil E. Coordination of healthcare for transsexual persons: a multidisciplinary approach. Curr Opin Endocrinol Diabetes Obes. 2013;20:585-91. FI: 3,985(Q2)

Fernández-Rebollo E, Lecumberri B, Gaztambide S, Martinez-Indart L, Perez de Nanclares G, Castaño L. Endocrine Profile and Phenotype-(Epi)Genotype Correlation in Spanish Patients with Pseudohypoparathyroidism. J Clin ndocrinol Metab. 2013;98:996-1006. FI: 6,430(Q1)

Garcia Castano A, Pérez de Nanclares G, Madariaga L, Aguirre M, Madrid A, Nadal I, et al: RenalTube Grp. Genetics of Type III Bartter Syndrome in Spain, Proposed Diagnostic Algorithm. PLoS One.2013;8:e74673. FI: 3,730(Q1)

García-Rodríguez JL, Barbier-Torres L, Fernández-Álvarez S, Juan VG, Monte MJ, Halilbasic E, et al. SIRT1 controls liver regeneration by regulating BA metabolism through FXR and mTOR signaling. Hepatology 2013 : -0. FI: 12,003(Q1).

Gaztambide S, Vazquez F, Castano L. Diagnosis and treatment of multiple endocrine neoplasia type 1 (MEN1). Minerva Endocrinol. 2013;38:17-28. FI: 1,396(Q4)

Gil-Pena H, Renaltube Grp. RenalTube: Online website-based collaborative effort for the clinical and molecular study of primary tubular disorders. Pediatr Nephrol. 2013;28:1466. FI: 2,939(Q1). ( Meeting Abstract)

Gutiérrez-Repiso C, Rojo-Martínez G, Soriguer F, García-Fuentes E, Vendrell J, Vázquez JA, et al. Factors affecting levels of urinary albumin excretion in the general population of Spain: the Di@bet.es study. Clin Sci. 2013;124:269-77. FI: 4,859(Q1)

Hirschler V, Maccallini G, Sanchez MS, Castano L, Molinari C, San Antonio de los Cobres Study Gr. Improvement in High-Density Lipoprotein Cholesterol Levels in Argentine Indian School Children after Vitamin D Supplementation. Horm Res Paediatr. 2013;80:335-42. FI: 1,553(Q2).

Lehtonen E, Ormisson A, Nucci A, Cuthbertson D, Sorkio S, Hyytinen M, et al. Use of vitamin D supplements during infancy in an international feeding trial. Public Health Nutr. 2013:-. FI: 2,250(Q2)

Madariaga L, Garcia-Castano A, Perez-Nanclares G, Nadal I, Aguirre M, Castano L, et al Grp RENALTUBE. Long term prognosis of our cohort of patients with genetically confirmed Bartter syndrome (BS) type II & III. Pediatr Nephrol. 2013;28:1889-90. FI: 2,939(Q1). ( Meeting Abstract)

Marcuello C, Calle-Pascual AL, Fuentes M, Runkle I, Rubio MA, Montañez C, et al. Prevalence of the metabolic syndrome in Spain using regional cutoff points for waist circumference: the di@bet.es study. Acta Diabetol. 2013;50: 615-23. FI: 4,631(Q1)

Martinez-Una M, Varela-Rey M, Cano A, Fernandez-Ares L, Beraza N, Aurrekoetxea I, et al. Excess S-adenosylmethionine Reroutes Phosphatidylethanolamine Towards Phosphatidylcholine and Triglyceride Synthesis. Hepatology. 2013;58:1296-1305. FI: 12,003(Q1)

Martín-Núñez GM, Cabrera-Mulero R, Rojo-Martínez G, Gómez-Zumaquero JM, Chaves FJ, de Marco G, et al. Polymorphisms in the SCD1 gene are associated with indices of stearoyl CoA desaturase activity and obesity: A prospective study. Mol Nutr Food Res. 2013;7:2177-84. FI: 4,310(Q1)

Mejia N, Santos F, Claverie-Martin F, Garcia-Nieto V, Ariceta G, Castano L, RenalTube Grp. RenalTube: a network tool for clinical and genetic diagnosis of primary tubulopathies. Eur J Pediatr. 2013;172:775-80. FI: 1,907(Q2)

Moran A, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, et al; AIDA Study Group. Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials. Lancet. 2013;381:1905-15. FI: 39,060(Q1)

Ortega E, Franch J, Castell C, Goday A, Ribas-Barba L, Soriguer F, et al. Mediterranean Diet Adherence in Individuals with Prediabetes and Unknown Diabetes: The Di@bet.es Study. Ann Nutr Metab. 2013;62:339-46. FI: 1,661(Q3)

Rojo-Martinez G, Valdes S, Colomo N, Lucena MI, Gaztambide S, Gomis R, et al. Use of Drugs Related to the Treatment of Diabetes Mellitus and Other Cardiovascular Risk Factors in the Spanish Population. The Di@bet.es Study. Rev Esp Cardiol. 2013;66:854-63. FI: 3,204(Q2)

Rojo-Martinez G, Soriguer F, Colomo N, Calle A, Goday A, Bordiu E, et al: Di Bet Es Study Grp. Factors determining high-sensitivity C-reactive protein values in the Spanish population. Di@bet.es study. Eur J Clin Invest. 2013;43: 1-10. FI: 3,365(Q1)

Rouco I, Hurtado P, Castaño L, Zarranz JJ. Experience with immunotherapy in 3 patients with cerebellar ataxia associated with anti-glutamic acid decarboxylase antibodies. Neurologia 2013. : -0. FI: 1,322(Q3)

Rubio-Martín E, Soriguer F, Gutiérrez-Repiso C, Garrido-Sánchez L, de Adana MS, García-Fuentes E, et l. C-reactive protein and incidence of type 2 diabetes in the Pizarra study. Eur J Clin Invest. 2013;43:159-67. FI: 3,365(Q1)

Rueda Y, Garcia-Arcos I, Aspichueta P, Ochoa B, Palacios L, Fresnedo O. Infection of primary hepatocytes with adenoviral vectors alters biliary lipid metabolism. J Physiol Sci. 2013;63:225-9. FI: 1,089(Q4)

Sesmilo G, Gaztambide S, Venegas E, Pico A, del Pozo C, Blanco C, et al, Webb SM, REA Investigators. Changes in acromegaly treatment over four decades in Spain: analysis of the Spanish Acromegaly Registry (REA). Pituitary. 2013;16:115-21. FI: 2,667(Q2)

Soriguer F, Colomo N, Olveira G, Garcia-Fuentes E, Esteva I, Ruiz de Adana MS, et al. White rice consumption and risk of type 2 diabetes. Clin Nutr. 2013;32:481-4. FI: 3,298(Q1)

Soriguer F, Gutiérrez-Repiso C, Rubio-Martín E, García-Fuentes E, Almaraz MC, Colomo N, et al. Metabolically Healthy but Obese, a Matter of Time? Findings From the Prospective Pizarra Study. J Clin Endocrinol Metab. 2013;98:2318-25. FI: 6,430(Q1)

Soriguer F, Rojo-Martinez G, Goday A, Bosch-Comas A, Bordiu E, Caballero-Diaz F, et al. Olive oil has a beneficial effect on impaired glucose regulation and other cardiometabolic risk factors. Di@bet.es study. Eur J Clin Nutr. 2013;67:911-6. FI: 2,756(Q2)

Tijero B, Gómez-Esteban JC, Lezcano E, Fernández-González C, Somme J, Llorens V, et al. Cardiac sympathetic denervation in symptomatic and asymptomatic carriers of the E46K mutation in the alpha synuclein gene. Parkinsonism Relat Disord. 2013;19:95-100. FI: 3,274(Q2)

Vazquez-Chantada M, Gonzalez-Lahera A, Martinez-Arranz I, Garcia-Monzon C, Regueiro MM, Garcia-Rodriguez JL, et al. Solute Carrier Family 2 Member 1 Is Involved in the Development of Nonalcoholic Fatty Liver Disease. Hepatology. 2013;57:505-14. FI: 12,003(Q1)